Protein Alignment Ir75c and glr-8

DIOPT Version :10

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 92/422 - (21%)
• Similarity: 162/422 - (38%)
• Gaps: 52/422 - (12%)

  Fly   228 MDSISRIGNRLIMHTQEILGFKLHYIW----CGTWSVQDAFGGAIGMLTNESAELCTTPFVPSWN 288
            |:.:..||.||.: |.|||. .|...|    .|:|:      ||.|.|.....:|.....:..::
 Worm    97 MEILKEIGKRLNL-TYEILP-ALGSTWGEYLNGSWT------GAFGQLVRGEVDLLAGGAIMEYD 153

  Fly   289 RLHYLHPMTEQAQFRAV-CMFRTPHN-AGIKAAVFLEPFMPSVWFAFAGLLIFAGVLLWMIFHLE 351
            | ..:..:|...||... .|.|:|.. ......:..|||...||...|.:::.:||:..::.::.
 Worm   154 R-SVIADLTYPFQFEPTGIMIRSPEKYEDDTLLIVTEPFSWEVWVITAAVILISGVIFLVMTNII 217

  Fly   352 RHWMQRCLDFIPSLLSSCLISFGAACIQGSYLMPKSAGGRLAFIAVMLTSFLMYNYYTSIVVSTL 416
            |...:   :...:...|..:.|.....||....|:|...|:......|.|..:...:|..:|:..
 Worm   218 RKVYE---EMTVTPFESIWVFFSIFVQQGLPEQPRSWSCRVLVALWWLASITLSATFTGSLVALF 279

  Fly   417 LGSPVRSNIRTIQQLA----DSSLDVGFDTVPFTKTYLVS-SPRPDIRSLYKQKVESKRDP--NS 474
            .........:.|.||.    ....::..|...||:|.::: |..|..|.|:.:.:.:.:..  |.
 Worm   280 AVDKTNVPFQNIDQLVRLVKQGKFEIVMDENSFTRTEMIARSKLPVYRDLWHEMIVNHKVKYVNG 344

  Fly   475 VWLSPEEGVIRVRDQPGFVYTSEASFMYHFVEKHYLPREISDLNEIILRPESAVYGMVHL--NST 537
            :    ..||..||..||:......:.:..:.   |...::...|:.||    .||..:.|  ||.
 Worm   345 I----ARGVAFVRANPGYALLGPMATLNFYA---YSDCKVILFNDGIL----PVYLSIPLVKNSI 398

  Fly   538 YRQLLTQLQVRMLETGITSK----QSRFFSKTKLHTFSNSFVI----QVGMEYAAPLFISLLVAY 594
            |....:.....|:|.|.|.|    ...:.:..|::. .||..|    .:.::.|...|...|...
 Worm   399 YSPYFSTKIREMVERGFTQKWIADYRSYVAMQKINE-CNSTTIGPKSYLDLKRAQGAFWVFLGGA 462

  Fly   595 FLALLILILEICWARYAKK-----KFSTIIPQ 621
            .|.|.:.:.|..:..:.:|     |.:|:.|:
 Worm   463 GLGLALFVGEFIFKFFREKMTKHTKTTTVPPE 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..>508	CDD:459656	35/186 (19%)
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	78/349 (22%)