Protein Alignment Ir75c and glr-4

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001254126.1
• Gene: glr-4 / 174258
• WormBaseID: WBGene00001615
• Length: 951
• Species: Caenorhabditis elegans
• Alignment Length: 679
• Identity: 138/679 - (20%)
• Similarity: 241/679 - (35%)
• Gaps: 210/679 - (30%)

  Fly    13 NLLEINLSNL--MVFHCWSIKEAFPLVEMLNQNGIFSQYIDVQNPDNLANVHKEYLDSD---LVR 72
            :|||..|:|:  ..|||             |..|:.....|......||      |.|:   :|.
 Worm   255 SLLEDFLNNMYGASFHC-------------NITGLQLVKNDPMMKTQLA------LTSEAVYVVG 300

  Fly    73 LGVF--LDLG---------CDKAELVTNQSSRARLYNQNLHWLLYDEAGNFTKLTQLFEGANLSL 126
            :.::  .:||         ||..::    .|..|:.|:.:..|         ||..       .|
 Worm   301 MSIYRMRELGHAPRQSSIMCDSHDI----WSDGRIMNEGIRKL---------KLRN-------QL 345

  Fly   127 NADVTYVSREDEERFILHDV------------------YNKGSHLGGKLNITVDQTLQCNRSHCQ 173
            ..||.:.|..:.:..:.|.|                  :|..|....:....:|..
 Worm   346 TGDVQFKSNGERDDIMYHGVGRINSQFVKLGNWSEKRGWNFDSRYANRWEFDIDPD--------- 401

  Fly   174 VKEYLSELHLRPRLQHRMDLSSVTFRLAALVSVLPINSSEEELLEFLNSDRDSHMDSISRIGNRL 238
             .|.|..||||          .|.:.....|.....|..|...::.||     .|..:.:. |..
 Worm   402 -SEDLEGLHLR----------VVVYLEEPFVIKTGENQYEGFCIDLLN-----EMTQVLKF-NYT 449

  Fly   239 IMHTQEILGFKLHYIWCGTWSVQDAFG---GAIGMLTNESAELCTTPFVPSWNR-------LHYL 293
            |:..|:           ||:.::|..|   |.||.|....|:|..:....:::|       |.::
 Worm   450 IIEVQD-----------GTYGIEDESGRWNGIIGALQRHEADLSLSAVTITYSRAEVVDFTLPFM 503

  Fly   294 HPMTEQAQFRAVCMFRTPHNAGIKAAV--FLEPFMPSVWFAFAGLLIFAGVLLWMI--------- 347
            |...      ::.:.||..... |.::  ||||...:||.:   |||...::.:.:
 Worm   504 HLGI------SILLARTSEETD-KGSLWTFLEPLSLTVWIS---LLISYCIVSYSMHILAKFSPY 558

  Fly   348 --FHLERHWMQRCLDFIP------SLLSSCLISFGAACIQGSYLMPKSAGGRLAFIAVMLTSFLM 404
              ::||| ..:|..:.|.      ::|:|...:.|:...|||.::|::|..||..:...:.:.::
 Worm   559 EWYNLER-IDERDFENIKNQKNQFTVLNSFWFTMGSLMQQGSDVIPRAAATRLIAVVWWMFTQII 622

  Fly   405 YNYYTSIVVSTLLGSPVRSNIRTIQQLAD-SSLDVGFDTVPFTKTYLVSSPRPDIRSLYKQ--KV 466
            .:.||:.:.:.|....:.:.|.:.|.||: ..:..|......|..:...|..|    :|::  .|
 Worm   623 ISSYTAQLAAFLTVERMSTPIESTQDLANQQKIRYGVLKSGSTMDFFRESKIP----MYERMWSV 683

  Fly   467 ESKRDPNSVWLSPEEGVIRVRDQPGFVYTSEASFMYHFVEKHYLPREISDLNEIILRPESAVYGM 531
            .....|.....|..||:.||: ..|:.|..|:|.:.:::|:..   |:..:..::   :|..||:
 Worm   684 MESSSPGVFVNSSREGIARVK-SGGYAYMMESSMLEYYLERDC---ELQSIGGLL---DSKGYGI 741

  Fly   532 -VHLNSTYRQLLT----QLQVRML-----------------------ETGITSKQSRFFSKTKLH 568
             :...|..|.:|:    |||.|.:                       |....||....|
 Worm   742 ALPKGSPLRDILSRTVLQLQERTILEALKNKWWRDRREGPSCGPPPSEKATNSKPQNIF------ 800

  Fly   569 TFSNSFVIQVGMEYAAPLFISLLVAYFLA 597
                      |:.|.  |...|:||:.||
 Worm   801 ----------GIFYV--LLTGLIVAFLLA 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	56/272 (21%)
glr-4	NP_001254126.1	PBP1_iGluR_Kainate	30..385	CDD:107377	32/168 (19%)
		ANF_receptor	45..365	CDD:279440	31/148 (21%)
		Periplasmic_Binding_Protein_Type_2	410..775	CDD:304360	87/413 (21%)
		Lig_chan	533..810	CDD:278489	62/309 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010