Protein Alignment Ir75c and glr-3

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_492017.3
• Gene: glr-3 / 172449
• WormBaseID: WBGene00001614
• Length: 836
• Species: Caenorhabditis elegans
• Alignment Length: 631
• Identity: 127/631 - (20%)
• Similarity: 233/631 - (36%)
• Gaps: 145/631 - (22%)

  Fly    54 NPDNLANVHKEYLDSDLVRL---GV--FLDLGCDKAELVTNQSSRARLYNQ---NLHWLLYDEAG 110
            |.:.:.::.:|.:....:||   ||  ...:..|...|:.......:::::   ...|    ::|
 Worm   267 NSEYIEDIRQEIVHKSSIRLPKKGVPYTTSIWIDTLRLLIRSMKSIQIWDEPRCGSSW----KSG 327

  Fly   111 NFTKLTQLFEGANLSLNADVTYVSREDEERFILHDVYNKGSHLGGKLNITVDQTLQCNRSHCQVK 175
            :..| .:.||.....::.|:.:....:...:.|| ||.:              ||.
 Worm   328 SDIK-KRFFENPLAGISGDLHWAPSGERSNYTLH-VYRR--------------TLS--------- 367

  Fly   176 EYLSELHLRPRLQHRMDLSSVTFRLAALVSVLPINSSEEELLE-------------FL----NSD 223
                       .|...:.||.|.|:|:..:|:..||||:..||             |:    |..
 Worm   368 -----------FQKFAEWSSRTRRIASSEAVVIANSSEKLTLEGKHLKISVYLEAPFVMITSNGS 421

  Fly   224 RDSH-MDSISRIGNRLIMHTQEILGFKLHYIWCGTWSVQ----DAFG---------GAIGMLTNE 274
            .:.: :|.:.:|.|        ||.|        |:::|    :|:|         |.:|.|...
 Worm   422 YEGYCIDLLHKIAN--------ILKF--------TYTIQKVRDNAYGSKESNGKWSGMVGELQRG 470

  Fly   275 SAELCTTPFVPSWNRLHYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVW-FAFAGLLI 338
            .|:|.......|:.|...:.............:|:.|.........|::|....|| ..||...:
 Worm   471 DADLAVASLTISYGRSEVIDFTVPYMHLGISILFKKPRIRDSDWFKFMDPLSTQVWIMTFASYFV 535

  Fly   339 FAGVLLWMIFHL---------ERHWMQRCLDFIPSLLSSCLISFGAACIQGSYLMPKSAGGRLA- 393
             ..|.:|:|..:         |.:...:.:|...||.:|...:..:...|||.|.|::|..||.
 Worm   536 -VSVAIWIIAKISPYEQFERDEDNGQYKPVDNQFSLRNSFWFTVCSLMQQGSELCPRAASTRLLT 599

  Fly   394 ----FIAVMLTSFLMYNYYTSIVVSTLLGSPVRSNIRTIQQLADSSLDVGFDTVPFTKTYLVSSP 454
                |.|::|.|     .||:.:.:.|....:.:.|.....||..           ||....:..
 Worm   600 GIWWFFALILIS-----SYTANLAAVLTTRRMETPIENADDLAAQ-----------TKIKYGTLG 648

  Fly   455 RPDIRSLYKQ-KVES--------KRDPNSVWLSPEEGVIRVRDQPGFVYTSEASFMYHFVEKHYL 510
            |....|.:.: |:|:        ...|.....|.:||:.||:.. .:.|..|:|.:.:.||:..
 Worm   649 RGSTMSFFNESKIETYERMWQLMSSSPGLFVQSSKEGIARVKSS-DYAYLMESSMLEYAVERDC- 711

  Fly   511 PREISDLNEIILRPESAVYGM-VHLNSTYRQLLTQLQVRMLE-TGITSKQSRFFSKTKLHTFSNS 573
              |:..:..:|   :...||: :...|.||:|::...:|:.| |.:|..:.:::....:......
 Worm   712 --ELMQIGGLI---DQKGYGIGLPKGSPYRELISTAILRLQEKTELTELKEKWWKDKSVVCEQPK 771

  Fly   574 FVIQVGMEYAAPLFISLLVAYFLALLILILEICWARYAKKKFSTII 619
            ...|...|....:||.|:|...|..:::|.|:...|......|.:|
 Worm   772 RKDQDDGESIGGIFIILVVGLVLTAVLVIFELITTRKPSPAQSQVI 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	57/250 (23%)
glr-3	NP_492017.3	PBP1_iGluR_non_NMDA-like	21..385	CDD:380591	26/157 (17%)
		Periplasmic_Binding_Protein_Type_2	401..761	CDD:419667	82/399 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910