Protein Alignment Ir75c and Grin3b

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_006513350.1
• Gene: Grin3b / 170483
• MGIID: 2150393
• Length: 1138
• Species: Mus musculus
• Alignment Length: 437
• Identity: 86/437 - (19%)
• Similarity: 141/437 - (32%)
• Gaps: 135/437 - (30%)

  Fly   228 MDSISRIGNRLIMHTQEILGFKLHYIWCGTW-SVQDA-FGGAIGMLTNESAELCTTPFVPSWNRL 290
            :|.:.|:...|      ...|:|:.:..|.: :::|. :.|.:|.|....|.:..|.|..:..|.
Mouse   561 IDLLERLAEDL------AFDFELYIVGDGKYGALRDGRWTGLVGDLLAGRAHMAVTSFSINSARS 619

  Fly   291 HYLHPMTEQAQFRAVCMFRTPHNAGIKAAVFLEPFMPSVWFAFAGLLIFAGVLLWMIFHLERHW- 354
            ..:...:.........|.||...|. ....|:.|...|:|..     :||.:.|..:|.....|
Mouse   620 QVVDFTSPFFSTSLGIMVRTRDTAS-PIGAFMWPLHWSMWVG-----VFAALHLTALFLTLYEWR 678

  Fly   355 ---------MQRCLDF-IPSLLSSC-LISFGAACIQGSYLMPKSAGGRLAFIAVMLTSFLMYNYY 408
                     ..|...| ..|.|:.| .|.||...   |...||...||.......:...|:.:.|
Mouse   679 SPYGLTPRGRNRGTVFSYSSALNLCYAILFGRTV---SSKTPKCPTGRFLMNLWAIFCLLVLSSY 740

  Fly   409 TSIVVSTLLGSPVRSNIRTIQQLA---DSSLDVGFDTVPFTKTYLVSSPRPDIRSLYKQKVESKR 470
            |:.:.:.::|.      :|.::|:   |..|               ..|....|.
Mouse   741 TANLAAVMVGD------KTFEELSGIHDPKL---------------HHPSQGFRF---------- 774

  Fly   471 DPNSVWLSPEEGVIRVRDQPGFVYTSEASF--MYHFVEKHYLPRE-------ISD---LNEIILR 523
              .:||.|..|..|:            |||  |:..:.:|..|..       .||   ||..|:.
Mouse   775 --GTVWESSAEAYIK------------ASFPEMHAHMRRHSAPTTPHGVAMLTSDPPKLNAFIMD 825

  Fly   524 PESAVYGMVHLNSTYRQLLTQLQVRMLETG-----------------ITSKQSRFFSKTK----- 566
            .....|          ::......::|..|                 :||..|.|.|:.|
Mouse   826 KSLLDY----------EVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFI 880

  Fly   567 --LH------------TFSNSFVIQVGMEYAAPLFISLLVAYFLALL 599
              ||            .|:.:..:|:|:.:.:.||:.|.:....|||
Mouse   881 DLLHDKWYKMVPCGKRVFAVTETLQMGVYHLSGLFVLLCLGLGSALL 927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	48/251 (19%)
Grin3b	XP_006513350.1	PBP1_iGluR_NMDA_NR3	141..481	CDD:380600
		PBP2_iGluR_NMDA_Nr3	494..888	CDD:270438	77/396 (19%)
		Lig_chan	656..922	CDD:365843	63/328 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846357
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830