Protein Alignment Ir75c and grin2b

DIOPT Version :9

• Sequence 1: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_017948700.2
• Gene: grin2b / 100490580
• XenbaseID: XB-GENE-949327
• Length: 1449
• Species: Xenopus tropicalis
• Alignment Length: 754
• Identity: 147/754 - (19%)
• Similarity: 248/754 - (32%)
• Gaps: 262/754 - (34%)

  Fly     4 WPLYRLI------------VFNLLEINLSNLMVFHCWSIKEAFPLVEMLNQNGIF---------- 46
            |.|..:|            :.|.|:...|.:::.:| :.:||..:.|:.:..|:.
 Frog   192 WELEEVIHLDMSLDDNDSKIQNQLKKLQSPVILLYC-TKEEATYIFEVAHSVGLTGYGYTWIVPS 255

  Fly    47 -----SQYIDVQNPDNLANVHKEYLDSDL---VRLGVFLDLGCDKAELVTNQS-----------S 92
                 :..:..:.|..|.:|..:..|.||   ||.|:.:........|..:.|           .
 Frog   256 LVAGDTDTVPAEFPTGLISVSYDEWDYDLPARVRDGIAIITTAASTMLSEHNSIPQSKSSCYNIQ 320

  Fly    93 RARLYNQNL--HWLLYDEAGNFTKLTQLFEGANLSLNADVTYVSREDEERFILHDVYNKGSHLGG 155
            .:|:|..::  .:|:     |.|     |||.|||.:.|                    |..:..
 Frog   321 ESRVYEAHMLKRYLI-----NVT-----FEGRNLSFSED--------------------GYQMHP 355

  Fly   156 KLNITVDQTLQCNRSHCQVKEYLSE-----------LHLRPRLQHRMD--LSSVTFRLAALVSVL 207
            ||.|.:   |...|...:|.:|...           ..|.|..:...|  ||.||...|..|.|.
 Frog   356 KLVIIL---LNQQRKWERVGKYKDRSLKMKYYVWPVFELYPNSEEHKDEHLSIVTLEEAPFVIVE 417

  Fly   208 PI---------------------NSSEEELLEFLNSDRDSHMDSISRIGNRLIMHTQEIL----- 246
            .:                     |.:||.........:...:|.:.:|. :.:..|.::.
 Frog   418 DVDPLSGTCMRNTVPCRKQIRTENRTEEGGNYIKRCCKGFCIDILKKIA-KTVKFTYDLYLVTNG 481

  Fly   247 --GFKLHYIWCGTWS------VQDAFGGAIGMLT--NESAELC--TTPFVPSWNRLHYLHPMTEQ 299
              |.|::    |||:      |......|:|.||  .|.:|:.  :.||:.:
 Frog   482 KHGKKIN----GTWNGMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIET------------- 529

  Fly   300 AQFRAVCMFRTPHNAGIKAAVFLEPFMPSVW-FAFAGLLIFAGVLLWMIFHLERHWMQRCL---- 359
                .:.:..:..|..:..:.|||||...|| ..|..|||.:.|.:::..:.......|||
 Frog   530 ----GISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGR 590

  Fly   360 -DFIPSL-------LSSCLISFGAACIQGSYLMPKSAGGRL-----AFIAVM--------LTSFL 403
             ...||.       |...|:...:..:|.    ||....::     ||.||:        |.:|:
 Frog   591 EPGGPSFTIGKAIWLLWGLVFNNSVPVQN----PKGTTSKIMVSVWAFFAVIFLASYTANLAAFM 651

  Fly   404 MYNYYTSIVVSTLLGSPVRSNIRTIQQLADSSLDVGFDTVPFTKTYLVSSPRPDIRSLYKQKVE- 467
            :...|.. .||.|       :.:..|:..|.|....|.|||      ..|...:||:.|.:...
 Frog   652 IQEEYVD-QVSGL-------SDKKFQRPNDFSPAFRFGTVP------NGSTERNIRNNYLEMHSY 702

  Fly   468 ----SKRDPNSVWLSPEEGVIRVRDQPGFVYTSEASFMYHFVEKHYLPREISDLNEIILRPE--- 525
                ::|......||.:.|.:     ..|:|                  :.:.||.:..|.|
 Frog   703 MVKFNQRSVQDALLSLKTGKL-----DAFIY------------------DAAVLNYMAGRDEGCK 744

  Fly   526 -----------SAVYGM-VHLNSTYR--------QLLTQLQVRMLE----TGITSKQSRFFSKTK 566
                       :..||: :..:|.::        ||....::..||    |||
 Frog   745 LVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGI------------ 797

  Fly   567 LHTFSNSFV-IQVGMEYAAPLFISLLVAYFLALLILILE 604
            .|...|..: .|:.::..|.:|..|..|..|:|:..|:|
 Frog   798 CHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIME 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75c	NP_649013.3	Lig_chan	328..553	CDD:306551	55/282 (20%)
grin2b	XP_017948700.2	PBP1_iGluR_NMDA_NR2	28..383	CDD:380601	42/224 (19%)
		PBP2_iGluR_NMDA_Nr2	400..800	CDD:270436	92/474 (19%)
		NMDAR2_C	837..1449	CDD:402274	147/754 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910