DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir75a and GLR3.4

DIOPT Version :9

Sequence 1:	NP_649012.2	Gene:	Ir75a / 39982	FlyBaseID:	FBgn0036757	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001030971.1	Gene:	GLR3.4 / 839268	AraportID:	AT1G05200	Length:	959	Species:	Arabidopsis thaliana

Alignment Length:	365	Identity:	79/365 - (21%)
Similarity:	138/365 - (37%)	Gaps:	57/365 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 VGAVVDQTADLTATPSLATEGRLKYL---SAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLV 337
            |..||....|:..........|.:|:   ...||:|    :.:......|......||:||:..:
plant   556 VNEVVADNFDVAVGDITIVTNRTRYVDFTQPFIESG----LVVVAPVKEAKSSPWSFLKPFTIEM 616

  Fly   338 WYLFGGVLSLIGVLLWITFYMECKRMQKRWRLDYLPSLLSTFLISFGAACIQSSSLIPRSAGGRL 402
            |.:.||....:|.::||..:    |..:.:|......|::.|..||.............|.|..:
plant   617 WAVTGGFFLFVGAMVWILEH----RFNQEFRGPPRRQLITIFWFSFSTMFFSHRENTVSSLGRFV 677

  Fly   403 IYFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAESSLTVGLEPLPFTKSYLNYSRLPE 467
            :...||:: .|:.:.||:.:.|.|....:.|:|:.:..|..|:..:|::...|.::||    :.|
plant   678 LIIWLFVV-LIINSSYTASLTSILTIRQLTSRIEGIDSLVTSNEPIGVQDGTFARNYL----INE 737

  Fly   468 IHLFIKRKIESQTQNPELWLPAEQ------GVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICD 526
            :::...|.:  ..::.|.:|.|.|      ||..:.|...|:.|..|:|.             |.
plant   738 LNILPSRIV--PLKDEEQYLSALQRGPNAGGVAAIVDELPYIEVLLTNSN-------------CK 787

  Fly   527 LNEVLFRPEQLFYTH------LHRNSTYKELFRLRFLRILETGVYRKQRSYWVHMKLHCVAQNFV 585
                 ||.....:|.      ..|:|..........|::.|.|...|....|::.|..|..|
plant   788 -----FRTVGQEFTRTGWGFAFQRDSPLAVDMSTAILQLSEEGELEKIHRKWLNYKHECSMQ--- 844

  Fly   586 ITVGMEYVAPLL----LMLICADILVVVILLVELAWKRFF 621
            |:...:....|.    |.|||.  :...:.|....|:.|:
plant   845 ISNSEDSQLSLKSFWGLFLICG--ITCFMALTVFFWRVFW 882

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	61/281 (22%)
GLR3.4	NP_001030971.1	PBP1_GABAb_receptor_plant	62..450	CDD:380645
		Periplasmic_Binding_Protein_Type_2	<518..591	CDD:389745	8/34 (24%)
		Lig_chan	615..869	CDD:365843	62/287 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910