DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir75a and GLR2.4

DIOPT Version :9

Sequence 1:	NP_649012.2	Gene:	Ir75a / 39982	FlyBaseID:	FBgn0036757	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001328410.1	Gene:	GLR2.4 / 829299	AraportID:	AT4G31710	Length:	912	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	105/559 - (18%)
Similarity:	185/559 - (33%)	Gaps:	156/559 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 TQPTLAIYVDIKCDQTQDLLEEASREQIYNQHYHWLLVG---------NQSKLEFYDLFGLFNIS 128
            |:||....|.:.......:..:|....:..|.|.|:|..         |.:.:|  .:.|:..|.
plant   242 TKPTRVFVVHMNRFLASRVFSKARETGLMKQGYAWILTNGVIDHLVLMNGTDIE--AMQGVIGIR 304

  Fly   129 IDADVSYVKEQIQ-----------------------DNNDSVAYAVHDVYNN----GKIIGGQLN 166
            ....:|   |::|                       |...::|.||.:....    .|:.|  .|
plant   305 THFPIS---EELQTFRSRLAKAFPVSELNIYGLRAYDATTALAMAVEEAGTTNLTFSKMDG--RN 364

  Fly   167 VTGSHEMSCDPFVCRRTRHLSSLQKRSKYGNRE----QLTDVVLRVATVVTQRPLTL----SDDE 223
            ::....:|...:..:..|.||.:|.:...|:..    ||...|..:..|:....:.:    .|..
plant   365 ISDLEALSVSEYGPKLIRSLSQIQFKGLSGDYHFVDGQLHASVFEIVNVIDGGGILVGFWTQDKG 429

  Fly   224 LIRFLSQENDT---------HIDSLARFGFHLTLILRDLLHCKMKFIFSDSW-----SKSDVVGG 274
            |::.||..:.|         |::.:...|..||:              ...|     .|...:|.
plant   430 LVKDLSPSSGTTRTFSSWKNHLNPILWPGITLTV--------------PKGWEIPTNGKELQIGV 480

  Fly   275 SVGA---VVDQTADLTATPSLATEGRLKYLSAIIETGFF------------------------RS 312
            .||.   .|..|.|.....::.|...:.:..|:|:...:                        ||
plant   481 PVGTFPQFVKVTTDPLTHETIVTGFCIDFFEAVIQAMPYDVSHRFIPFGDDDGKTNDTTILANRS 545

  Fly   313 VCI-FRTPH-------------NAGLRGDVFLQPFSPLVWYLFGGVLSLIGVLLWITFYMECKRM 363
            ..: |..|:             |......:|.:|.:|.:|.:..|...::|.::||        :
plant   546 SYVDFTLPYTTSGVGMVVPLKDNVARSSLIFFKPLTPGLWGMTLGSFFVVGFVVWI--------L 602

  Fly   364 QKRWRLDYLP----SLLSTFLISFGAACIQSSSLIPR----SAGGRLIYFALFLISFIMYNYYTS 420
            :.|...::..    .:.:.|..:|....     ..||    |...|::....:.|..::...||:
plant   603 EHRVNSEFTGPPQYQISTMFWFAFSIMV-----FAPRERVMSFTARVVVITWYFIVLVLTQSYTA 662

  Fly   421 VVVSSLLS----SPVKSKIKTMRQLAESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIESQTQ 481
             .:||||:    :|.::.||.:  ||:.. .|..:...|....|..|..||..|.   ...|..:
plant   663 -SLSSLLTTQQLNPTETSIKNV--LAKGG-PVAYQRDSFVLGKLRESGFPESRLV---PFTSPEK 720

  Fly   482 NPELWL--PAEQGVLRVRDNPGYVYVF--ETSSGYAYVE 516
            ..||..  |::.||........||.||  :....|..||
plant   721 CEELLNKGPSKGGVSAAFMEVPYVRVFLGQYCKKYKMVE 759

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	44/196 (22%)
GLR2.4	NP_001328410.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000