Protein Alignment Ir75a and grik5

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001315085.1
• Gene: grik5 / 798791
• ZFINID: ZDB-GENE-070821-6
• Length: 1067
• Species: Danio rerio
• Alignment Length: 674
• Identity: 127/674 - (18%)
• Similarity: 241/674 - (35%)
• Gaps: 194/674 - (28%)

  Fly    79 IYVDIKCDQTQDLLEEASREQIYNQHYHWLL-------------VGNQSKLEFYDLFGL------ 124
            |.:|.....:..:|::||...:.:..|.::|             |..||.:..:.:|..
Zfish   227 IIIDANASISYLILKKASELGMTSAFYKYILTTMDFPLLWLDDIVDEQSNIVGFSMFNTTHPFYL 291

  Fly   125 -----FNIS--------------------IDADVSYVKEQIQDNNDSVAYAVH-------DVYNN 157
                 .|:|                    .|| |..|...:|:.|.|....|.       .::.:
Zfish   292 EFIRSLNLSWREGCDINPYPGPALSSALLFDA-VHVVVSAVQELNRSQEIGVKPLSCTSPQIWQH 355

  Fly   158 GKIIGGQL------NVTGSHEMSCDPFVCRRTRHLSSLQKRSKYGNRE------------QLTDV 204
            |..:...|      .:||..|.:...   :||.:...:.::.:.|::|            ..|.:
Zfish   356 GTSLMNYLRMVEYDGLTGRVEFNSKG---QRTNYTLHILEKHRGGHKEIGIWYSNNTLLMNSTSL 417

  Fly   205 VLRVATVVTQRPL----TLSDDELIRFLSQENDTHIDSLARFGFHLTLILRDLLHCKMKFIF--- 262
            .:.|:..:..:.|    .|.:..::|.::.:.....:....|...:...|.|:|    ||.:
Zfish   418 DINVSETLANKSLIITTILENPYVMRKINYQEFEGNEQYEGFCVDMLRELSDIL----KFTYRIK 478

  Fly   263 ------------SDSWSKSDVVGGSVGAVVDQTADLTATPSLATEGRLKYLS-----AIIETGFF 310
                        :.||:      |.||.::::.|||.......|..|.|.:.     ..:.....
Zfish   479 LVDDGLYGAPEPNGSWT------GMVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLGISIL 537

  Fly   311 RSVCIFRTPHNAGLRGDVFLQPFSPLVW-YLFGGVLSLIGVLL---------WITFYMECKRMQK 365
            ..|.|.|.|....     ||.||||.|| ::....|::..||.         |...: .|.| ::
Zfish   538 YRVHIGRKPGYFS-----FLDPFSPAVWLFMLLAYLAVSCVLFLSARLSPYEWYNPH-PCLR-ER 595

  Fly   366 RWRLDYLPSLLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYTSVVVSSLLSSP 430
            |..|:...:|.::.....|....|.|.::||:...|.:....:..:.|:.:.||:.:.:.|....
Zfish   596 RDLLENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQR 660

  Fly   431 VKSKIKTMRQLAE------------SSLTVGLEPLPFTKS-YLNYSRLPEIHLFIKRKIESQTQN 482
            ::..|::...||:            |::|.      |..| |..|.|:.. :::.|:
Zfish   661 MEVPIESPDDLADQTNIQYGTIHGGSTMTF------FMNSRYQTYQRMWN-YMYSKQ-------- 710

  Fly   483 PELWLPA-EQGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEV---------------- 530
            |.:::.: |:|:.|| .|..|.::.|::     :..|..:.. |:|.::
Zfish   711 PSVFVKSTEEGIARV-VNSKYAFLLEST-----MNEYHRSLN-CNLTQIGGLLDTKGYGIGMPLG 768

  Fly   531 -LFRPE-QLFYTHLHRNSTYKELFRLRFLRILETGVYRKQRSYWVHMKLHCVAQNFVITVGMEYV 593
             .||.| .|....|..|:      ||..|:          |.:|...|......:....:|||.:
Zfish   769 SPFRDELSLAVLQLQENN------RLEILK----------RRWWEGGKCPKEEDHRAKGLGMENI 817

  Fly   594 APLLLMLICADILVVVILLVELAW 617
            ..:.::|||..|:.|.:.::|..|
Zfish   818 GGIFVVLICGLIIAVFVAVMEFVW 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	60/307 (20%)
grik5	NP_001315085.1	PBP1_iGluR_Kainate_KA1_2	38..412	CDD:107389	30/188 (16%)
		ANF_receptor	55..392	CDD:279440	28/168 (17%)
		Periplasmic_Binding_Protein_Type_1	<313..383	CDD:299141	13/73 (18%)
		Periplasmic_Binding_Protein_Type_2	427..797	CDD:304360	83/424 (20%)
		Lig_chan	558..828	CDD:278489	61/309 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591252
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840