Protein Alignment Ir75a and grik4

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_021322087.1
• Gene: grik4 / 556582
• ZFINID: ZDB-GENE-070821-5
• Length: 965
• Species: Danio rerio
• Alignment Length: 670
• Identity: 140/670 - (20%)
• Similarity: 246/670 - (36%)
• Gaps: 169/670 - (25%)

  Fly    76 TLAIYVDIKCDQTQDLLEEASREQIYNQHYHWLLVGNQ-SKLEFYDL---------FGLFNIS-- 128
            |..|.||.....:..:||.||...:.:.:|.::|...: |.|...||         |.:||.:
Zfish   212 TATIIVDANATMSHVILERASELGMLSVYYTYILTSLEFSLLRLDDLADQRVNIVGFSVFNRTHP 276

  Fly   129 -IDADVSYVKEQIQDNNDSVAY------------AVHDVYNNGKIIGGQLNVTGSHEMSCDPFVC 180
             ....|..:....|:|.|...:            |||.|....:.:....|| |:.::||..  .
Zfish   277 FFQDFVLSLNRSWQENCDHAPFAGTPLSSALLFDAVHTVVAAVQELNRSQNV-GATQLSCKS--S 338

  Fly   181 RRTRHLSSLQ---------------------KRSKYGNR-----------------EQ------- 200
            :...|.:||.                     :||.|..|                 ||
Zfish   339 KIWEHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALRIMQNSRDGLRQIGQWHSEQGLSMERK 403

  Fly   201 -----LTDVVLRVATVVTQRPLTLSDDELIRFLSQENDTHIDSLARF-GFHLTLI--LRDLLHCK 257
                 :||.:......:|    |:.::..:  :.:.|...::...|: ||.:.::  |.|:|..|
Zfish   404 LPSLNVTDTLFNTTLTIT----TILENPYV--MLRANHQELEGNDRYEGFCVDMLKELADILKFK 462

  Fly   258 MKF-IFSD----------SWSKSDVVGGSVGAVVDQTADLTATPSLATEGRLKYLS-----AIIE 306
            .:. :..|          :|:      |.||.::.:.|||.......|..|.|.:.     ..:.
Zfish   463 YRIRLVGDGVYGVPGANGTWT------GMVGELISRKADLAVAALTITAEREKVIDFSKPFMTLG 521

  Fly   307 TGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVW------YL-FGGVLSLIGVLLWITFYMECKRMQ 364
            ......|.|.|.|....     ||.||||.||      || ...||.|:..|....:|.....::
Zfish   522 ISIMYRVHIGRRPGYFS-----FLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYNPHPCLK 581

  Fly   365 KRWRL---DYLPSLLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYTSVVVSSL 426
            .|..|   .|  ||.::|....|....|.|::.||:...|.:....:..:.|:.:.||:.:.:.|
Zfish   582 GRCSLLINQY--SLGNSFWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFL 644

  Fly   427 LSSPVKSKIKTMRQLAESSLTV-----GLEPLPFTKS--YLNYSRL--------PEIHLFIKRKI 476
            ....::..|:::..||:.:...     |...:.|.::  |..|.|:        |.:  |:|
Zfish   645 TVQRMEVPIESVDDLADQTAIEYGTMHGGSTMTFFQNSRYQTYQRMWNFMYSKQPSV--FVK--- 704

  Fly   477 ESQTQNPELWLPAEQGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFY-T 540
                       ..|:|:.||. |..|.|:.|::....|.:|.      |:|.::....:...| .
Zfish   705 -----------STEEGIARVL-NSNYAYLLESTMNEYYRQRN------CNLTQIGGLLDTKGYGI 751

  Fly   541 HLHRNSTYKELFRLRFLRILETG-VYRKQRSYWVHMKLHCVAQNFVITVGMEYVAPLLLMLICAD 604
            .:...|.|::.|.|..||:.|.. :...:|.:|...|......:....:|||.:..:.::|:|..
Zfish   752 GMPLGSVYRDEFDLAILRLQEENRLEILKRKWWDGGKCPKEEDHRAKGLGMENIGGIFVVLVCGL 816

  Fly   605 ILVVVILLVELAWKRFFTRH 624
            ::.:.:.::|..|   ..||
Zfish   817 LVAIFMAVLEFVW---MLRH 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	63/292 (22%)
grik4	XP_021322087.1	Periplasmic_Binding_Protein_Type_1	26..400	CDD:324556	39/190 (21%)
		PBP2_iGluR_kainate_KA1	425..785	CDD:270442	86/397 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590959
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840