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Protein Alignment Ir75a and Grik2

DIOPT Version :9

Sequence 1:	NP_649012.2	Gene:	Ir75a / 39982	FlyBaseID:	FBgn0036757	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_062182.1	Gene:	Grik2 / 54257	RGDID:	2733	Length:	908	Species:	Rattus norvegicus

Alignment Length:	593	Identity:	121/593 - (20%)
Similarity:	218/593 - (36%)	Gaps:	174/593 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 LLEEASREQIYNQHYHWLLVGNQSKLEFYDLFGLFNISIDADVSYVKEQIQDNNDSVAYAVHDVY 155
            |::||          ||  .|...::.|....|| ....|.||..:||:..:.
  Rat   362 LIKEA----------HW--EGLTGRITFNKTNGL-RTDFDLDVISLKEEGLEK------------ 401

  Fly   156 NNGKIIG-----GQLNVTGSHEMSCDPFVCRRTRHLSSLQKRSKYGNREQLTDVVLRVATVVTQR 215
                 ||     ..||:|                       .|:.|....:||.:...:.:||
  Rat   402 -----IGTWDPASGLNMT-----------------------ESQKGKPANITDSLSNRSLIVT-- 436

  Fly   216 PLTLSDDELIRFLSQENDTHIDSLARFGFHLTLILRDL-----LHCKMKFIFSDSWSKSDVVGGS 275
              |:.::..:.|  :::|..:....||..:...:||:|     ...:::.:....:...|.|.|.
  Rat   437 --TILEEPYVLF--KKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQ 497

  Fly   276 ----VGAVVDQTADLTATPSLATEGRLK---YLSAIIETGFFRSVCIFRTPH--NAGLRGDVFLQ 331
                |..::|..|||...|...|..|.|   :....:..|.  |: ::|.|:  |.|:..  ||.
  Rat   498 WNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGI--SI-LYRKPNGTNPGVFS--FLN 557

  Fly   332 PFSPLVW-YLFGGVLSLIGVLLWITFYMECKRMQKRWRLDYLP--------------SLLSTFLI 381
            |.||.:| |:....|.:..||..|..:...:     |   |.|              :||::|..
  Rat   558 PLSPDIWMYVLLACLGVSCVLFVIARFSPYE-----W---YNPHPCNPDSDVVENNFTLLNSFWF 614

  Fly   382 SFGAACIQSSSLIPRSAGGRLI-----YFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQL 441
            ..||...|.|.|:|::...|::     :|.|.:||     .||:.:.:.|....::|.|.:...|
  Rat   615 GVGALMRQGSELMPKALSTRIVGGIWWFFTLIIIS-----SYTANLAAFLTVERMESPIDSADDL 674

  Fly   442 AESSLTVGLEPLPFTKSYLNYSRLPE---IHLFIKRKIE---------SQTQNPELWLPAEQGVL 494
            |:.           ||  :.|..:.:   :..|.|.||.         |..:...|....|:|:.
  Rat   675 AKQ-----------TK--IEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQ 726

  Fly   495 RVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFY-THLHRNSTYKELFRLRFLR 558
            ||..: .|.::.|:::    :|  |..|..|:|.::....:...| ......|.|::...:..|:
  Rat   727 RVLTS-DYAFLMESTT----IE--FVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQ 784

  Fly   559 ILETGVYRKQRSYWVHMKLHCVAQNF-------------VITVGMEYVAPLLLMLICADILVVVI 610
            :.|.|            |||.:.:.:             ...:|::.:..:.::|....:|.|.:
  Rat   785 LQEEG------------KLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFV 837

  Fly   611 LLVELAWK 618
            .:.|..:|
  Rat   838 AVGEFLYK 845

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.