Protein Alignment Ir75a and grin2da

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_009292354.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1916
• Species: Danio rerio
• Alignment Length: 609
• Identity: 123/609 - (20%)
• Similarity: 222/609 - (36%)
• Gaps: 177/609 - (29%)

  Fly   108 LLVGNQS-----KLEFYDLFGLFNISIDA-DVSYVKEQIQDNNDS-VAYAVHDV--YNNGK---I 160
            ::.|||:     ::.|:.     ||::.. |.|:       |||. :|..:.||  |..|:   .
Zfish   371 MMDGNQTQRVPGRIRFFS-----NITLSGRDYSF-------NNDGYLANPLLDVISYTAGRGWEE 423

  Fly   161 IGGQLNVTGSHEMSCDPFVCRRTRHLSSLQKRSKYG-------NREQLTDVVLRVATVVTQRPLT 218
            :|...|  |...:...|:              |:||       :.:.|..|.|.....|...|..
Zfish   424 VGWWEN--GVLRLRYPPW--------------SRYGPFLKPLDDSQHLRVVTLEERPFVIVEPAD 472

  Fly   219 LSDDELIRFLSQENDTHIDSL-ARFGFHLTLI---LRDLLHCKMKFIFSDSWSKSDVVG------ 273
            ......||          ||: .|...:.:::   ::.:.||...|........:.:||
Zfish   473 PGTGSCIR----------DSVPCRLPLNNSMVVEGIQSMKHCCKGFCIDVLKRLAKIVGFTYDLY 527

  Fly   274 ----------------GSVGAVVDQTADLTATPSLATEGR---LKYLSAIIETGFFRSVCIFRTP 319
                            |.||.||.:.||:........|.|   :::....:|||.  ||.:.|:
Zfish   528 LVTNGRHGKNIDGQWNGMVGEVVSKRADMAIGSLTINEERSEVVEFSVPFVETGI--SVMVSRS- 589

  Fly   320 HNAGLRGDVFLQPFSPLVW-YLFGGVLSLIGVLLWITFYMECKRMQKRWRLDYLPSLL------- 376
             |..:....||:|:||.|| .:|...||::.|.::|..:..        .:.|..||.
Zfish   590 -NGTVSPSAFLEPYSPAVWVMMFVMCLSVVAVTVFIFEFFS--------PVGYNRSLQSGKTAGG 645

  Fly   377 STFLISFGA----ACIQSSSL---IPRSAGGRL--IYFALFLISFIMYNYYTSVVVSSLLSSPVK 432
            |.|.|....    |.:.::|:   .||....::  :.:|.|.:.|:.  .||:.:.:.::.   :
Zfish   646 SKFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLA--SYTANLAAFMIQ---E 705

  Fly   433 SKIKTMRQLAESS----------LTVGLEPLPFTKSYLNYSRLPEIHLFI----KRKIESQTQNP 483
            ..|.|:..|::..          |..|..|...|:..:. |..|.:|.::    :|.:|...:|
Zfish   706 EYIDTVSGLSDKKFQHPTEQYPPLRFGTVPNGSTEENIR-SNYPNMHQYMVRNNQRGVEDAIEN- 768

  Fly   484 ELWLPAEQGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFYT-----HLH 543
                      |:......::|   .::...|:.|   ..|.|.:  :.....::|.|     .||
Zfish   769 ----------LKTGKLDAFIY---DAAVLNYMAR---KDEGCKV--MTIGSGKVFATTGYGVALH 815

  Fly   544 RNSTYKELFRLRFLRILETGVYRKQRSYWVHMKLHCVAQNFVITV-----GMEYVAPLLLMLICA 603
            :||.:|....|..|:::...........|    |..:..|..|.|     .::.:|.:..||:.|
Zfish   816 KNSRWKRPLDLALLQLVGDDEIDMLERLW----LSGICHNDKIEVMSSKLDIDNMAGVFYMLLVA 876

  Fly   604 DILVVVILLVELAWKRFFTRHLTF 627
                :.:.|:..||:     ||.:
Zfish   877 ----MGLSLLVFAWE-----HLVY 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	58/306 (19%)
grin2da	XP_009292354.1	PBP1_iGluR_NMDA_NR2	42..441	CDD:107373	20/97 (21%)
		PBP2_iGluR_NMDA_Nr2	452..851	CDD:270436	88/449 (20%)
		HisJ	<507..>590	CDD:223904	18/86 (21%)
		Lig_chan	605..877	CDD:278489	59/312 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591212
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830