Protein Alignment Ir75a and GluRIB

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Alignment Length: 847
• Identity: 149/847 - (17%)
• Similarity: 282/847 - (33%)
• Gaps: 282/847 - (33%)

  Fly    20 GFIVLFHCWQSDESLKFAQQFMKPIHPILVYHQFVQMRGVLNWSHLELSYMGHTQPTLA------ 78
            |:..:.:.:.|.:.|...||..:.:.|.....|...::.:.|.| :.:.:: ||...:.
  Fly   169 GWRKIIYLYDSHDGLLRLQQIYQGLRPGNESFQVELVKRISNVS-MAIEFL-HTLEQIGRFENKH 231

  Fly    79 IYVDIKCDQTQDLLEEASRE-QIYNQHYHWLLVGN------QSKL-------------------- 116
            |.:|...:..:.:|.:..|: ::..:.||:||.|.      :|::
  Fly   232 IVLDCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMDDRWESEIIEFGAINITGFRIVDTNRRL 296

  Fly   117 --EFYDLF-----------GLFNISIDADVSY----------------VKEQIQDN--------- 143
              ||||.:           |..:||..|.:.|                ..:|.::|
  Fly   297 VREFYDSWKRLDPQMSVGAGRESISAQAALMYDAVFVLVEAFNKILRKKPDQFRNNVQRRSQTLM 361

  Fly   144 -NDSVAYAVHDVYN---------NGKIIGG--QLNVTGSHEMSCDPFVC--------------RR 182
             ..:.|....|.||         ||...||  ..:..||..|:.....|              :.
  Fly   362 VAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDCNTAKGWVNAWEHGDKI 426

  Fly   183 TRHLSSLQKRS-----KYGNREQLTDVVLRVATVVTQRPLT----LSDDELIRFLS--------- 229
            :|:|..::...     |:.:..:..:..|.|..:.....:.    .:||..::.|:
  Fly   427 SRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWNDDAGLQPLNAKYVRLRPH 491

  Fly   230 ---QENDTHIDSL-----------ARFGFHL--------------TLILRDL-LHCKMKFIFSDS 265
               ::|.|:|.:.           ..||..|              .|:.::| ::.:::.:...:
  Fly   492 VEFEKNRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEGYCKDLADLLAKELGINYELRLVKDGN 556

  Fly   266 W--SKSDVVG---GSVGAVVDQTADLTATPSLATEGR---LKYLSAIIETGFFRSVCIFR----T 318
            :  .||...|   |.||.:|.:.||:.......|..|   :.:....:..|.  |:.|.:    |
  Fly   557 YGSEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFMSLGI--SIMIKKPVKQT 619

  Fly   319 PHNAGLRGDVFLQPFSPLVWYLFGGVLSLIGVLLWITFYMECKRMQKRWRLDY------------ 371
            |   |:..  |:.|.|..:|  ...:.|.|||.: :.|::. :.....|||..
  Fly   620 P---GVFS--FMNPLSQEIW--VSVIFSYIGVSI-VLFFVS-RFSPHEWRLVQQQPQQSQSPDPH 675

  Fly   372 -------------------LP-----------------------------------------SLL 376
                               ||                                         |:.
  Fly   676 AHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSVW 740

  Fly   377 STFLISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQL 441
            ::|..|..|...|...|.|||..||:...:.|..:.|:.:.||:.:.:.|....:.:.|.:...|
  Fly   741 NSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPEDL 805

  Fly   442 A-ESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIESQTQNPELWLPA-EQGVLRVRDNPG-YV 503
            | ::.:..|......|..:...|:: .:|   .:..|.......:::|. ::|:.|||::.| |.
  Fly   806 AMQTEVQYGTLLHGSTWDFFRRSQI-GLH---NKMWEYMNSRKHVFVPTYDEGIKRVRNSKGKYA 866

  Fly   504 YVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFYTHLHRN-------------STYKELFRLR 555
            .:.|:..     ..|..|:|.||..:|            .||             |..|:...|.
  Fly   867 LLVESPK-----NEYVNAREPCDTMKV------------GRNLDTKGFGIATPLGSALKDPINLA 914

  Fly   556 FLRILETGVYRKQRSYWVHMKLHCVAQNFVIT----VGMEYVAPLLLMLICADILVVVILLVELA 616
            .|.:.|.|...|.|:.|.:.|..|.......|    :.:..||.:..:||...::.|.:.::|..
  Fly   915 VLTLKENGELIKLRNKWWYEKAECSTHKDGETSHSELSLSNVAGIFYILIGGLLVSVFVAILEYC 979

  Fly   617 WK 618
            ::
  Fly   980 FR 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	67/357 (19%)
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	51/310 (16%)
		ANF_receptor	55..461	CDD:279440	49/293 (17%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	89/472 (19%)
		Lig_chan	632..967	CDD:278489	67/359 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840