Protein Alignment Ir75a and GluRIID

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_651982.1
• Gene: GluRIID / 44483
• FlyBaseID: FBgn0028422
• Length: 902
• Species: Drosophila melanogaster
• Alignment Length: 738
• Identity: 159/738 - (21%)
• Similarity: 295/738 - (39%)
• Gaps: 165/738 - (22%)

  Fly     6 LANFVLDNLVQ---SRIGFIVLFHCWQSDESLKFAQQFMK------PIHPILVYHQFVQMRGVLN 61
            :||.:.|.:.|   ||..|     |::|.|.||.....|.      |:..::.|
  Fly   142 IANALYDIVNQFEWSRFIF-----CYESAEYLKILDHLMTRYGIKGPVIKVMRY----------- 190

  Fly    62 WSHLELSYMGHTQPTL---------AIYVDIKCDQTQDLLEEASREQIYNQHYHWLLVGNQSKLE 117
                :|:..|:.:..|         .|.|........:||.:|.:..|.|:.|.: ::||.: |.
  Fly   191 ----DLNLNGNYKSVLRRIRKSEDSRIVVVGSTTGVAELLRQAQQVGIMNEDYTY-IIGNLN-LH 249

  Fly   118 FYDL----FGLFNISIDADVSYVKEQIQD---------------NNDS--------VAY-AVHDV 154
            .:||    :...||:.....|..:|:::|               |:.|        :.| ||..:
  Fly   250 TFDLEEYKYSEANITGIRMFSPDQEEVRDLMEKLHQELGESEPVNSGSTFITMEMALTYDAVRVI 314

  Fly   155 YNNGKIIGGQ---LNVTGSHEMSCDPFVCRRTRHLSSLQKRSK--------YGN-REQLT-DVV- 205
            ....|.:..|   ||.:..|: :..|.......::.||:.:.|        .|| |:..| ||:
  Fly   315 AETTKHLPYQPQMLNCSERHD-NVQPDGSTFRNYMRSLEIKEKTITGRIYFEGNVRKGFTFDVIE 378

  Fly   206 LRVATVVT------------QRP------LTLSDDELIR---------------FLSQENDTHID 237
            |:.:.:|.            |||      ..:.|..|:.               .|.:..||.|.
  Fly   379 LQTSGLVKVGTWEEGKDFEFQRPPQAVNFNDIDDGSLVNKTFIVLISVATKPYASLVESIDTLIG 443

  Fly   238 SLARFGFHLTLI--LRDLLHCKMKFIFSD------SWSK-SDVVGGSVGAVVDQTADLTATPSLA 293
            :....|:.:.||  |.|.|  ...|.|.|      |::| ::...|.:..:|:..|||..|....
  Fly   444 NNQFQGYGVDLIKELADKL--GFNFTFRDGGNDYGSFNKTTNSTSGMLKEIVEGRADLAITDLTI 506

  Fly   294 TEGRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFGGVLSLIGVLLWITFYM 358
            |..|.:.:...|.........::..|..|......|:.|||..||...|  ::.:||.|  .|::
  Fly   507 TSEREEVIDFSIPFMNLGIAILYVKPQKAPPALFSFMDPFSSEVWLYLG--IAYLGVSL--CFFI 567

  Fly   359 ECKRMQKRW-----------RLDYLPSLLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISF 412
            ..:.....|           .|:...::.::...:.||...|.|.:.|::...|.|....:..:.
  Fly   568 IGRLSPIEWDNPYPCIEEPEELENQFTINNSLWFTTGALLQQGSEIAPKALSTRTISAIWWFFTL 632

  Fly   413 IMYNYYTSVVVSSLLSSPVKSKIKTMRQLAES--SLTVGLEPLPFTKSYLNYSRLPEIHLFIKRK 475
            ||.:.||:.:.:.|......|.|.:::.||::  .:..|.:....|:::.:.|..|   ::||..
  Fly   633 IMVSSYTANLAAFLTIENPTSPINSVKDLADNKDDVQYGAKRTGSTRNFFSTSEEP---IYIKMN 694

  Fly   476 IESQTQNPELWLP-AEQGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFY 539
             |....:||:.:. .:|||.:|:....|.::.|::|    :| :.|.:| |:|.:|....::..|
  Fly   695 -EYLNAHPEMLMENNQQGVDKVKSGTKYAFLMESTS----IE-FNTVRE-CNLTKVGDPLDEKGY 752

  Fly   540 -THLHRNSTYKELFRLRFLRILETGVYRKQRSYW---VHMKLHCVAQ---NFVITVGMEYVAPLL 597
             ..:.:|..|::.|....|.:.|.||..:.::.|   |...: |.|:   :....:|::.::.:.
  Fly   753 GIAMVKNWPYRDKFNKALLELQEQGVLARLKNKWWNEVGAGV-CSAKSDDDGPSELGVDNLSGIY 816

  Fly   598 LMLICADILVVVILLVELAWKRF 620
            ::|:...|:.::|.:  |.|..|
  Fly   817 VVLVIGSIISIIISI--LCWCYF 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	61/286 (21%)
GluRIID	NP_651982.1	PBP1_iGluR_Kainate	35..397	CDD:107377	58/277 (21%)
		ANF_receptor	46..380	CDD:279440	56/260 (22%)
		PBP2_iGluR_Kainate	417..788	CDD:270432	86/386 (22%)
		Lig_chan	549..819	CDD:278489	60/284 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462733
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840