Protein Alignment Ir75a and Ekar

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 750
• Identity: 140/750 - (18%)
• Similarity: 275/750 - (36%)
• Gaps: 192/750 - (25%)

  Fly     5 QLANFVLDNLVQ----SRIGFIVLFHCWQSDESLKFAQQFMKPIHPILVYHQFVQMRGVLNWSHL 65
            ||.|:..::::|    :|.|   :.|  :.:..:....|..:.      :|..|.||.|...|::
  Fly   131 QLVNYAFNDVIQYLNWTRFG---ILH--EKENGIINLHQLSRS------FHGEVHMRQVSRDSYV 184

  Fly    66 EL--SYMG---HTQPTLAIYVDIKCDQTQDLLEEASREQIYNQHYHWLLVGNQSKLEFYDL---- 121
            ..  .:.|   |.     |.:|...:....||:...::|:....||:|.  ....||.|||
  Fly   185 SALNEFKGKEIHN-----IIIDTNSNGISILLKNILQQQMNEYKYHYLF--TSFDLETYDLEDFK 242

  Fly   122 FGLFNIS----ID-ADVSYVKEQIQDNNDSVAYAVHDVYNNGKIIGGQLNVTGSHEMSCDPFV-- 179
            :...||:    :| |||. ||:.::|    :....|.::....:   .|::..|..:..:|.:
  Fly   243 YNFVNITSFRLVDTADVG-VKQILKD----IGLYSHHIFKKPYL---NLHIKKSTILESEPALMF 299

  Fly   180 ------------CRRTRHLS----SLQKRSKYGNREQLTDVVLRVATVVTQRPLTLSDDELIRF- 227
                        ..::..|:    |.::.:.:.....|.:.:..|.......|:...|.:.::|
  Fly   300 DSVYVFAIGLQTLEQSHSLTLLNISCEEENSWDGGLSLINYLNAVEWKGLTGPIQFKDGQRVQFK 364

  Fly   228 -----LSQENDTHIDSLARFG---------------FHLTLILRDLL-------HCKMKFIFSDS 265
                 |.|.:...:......|               .::||::..:|       |....|..::.
  Fly   365 LDLIKLKQHSIVKVGEWTPHGHLNITEPSMFFDAGSMNVTLVVITILETPYVMMHYGKNFTGNER 429

  Fly   266 W------------------------------SKSDVVG---GSVGAVVDQTADL---TATPSLAT 294
            :                              :|....|   |.|..::...|||   :.|.:.|.
  Fly   430 FYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYAR 494

  Fly   295 EGRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFGGVLSLIG-VLLWITFYM 358
            |..:.:....:..|.  |: :|:.|.:...|...|:.|.:..:|     :..||. .|:.:..|:
  Fly   495 ESVIDFTKPFMNLGI--SI-LFKVPTSEPTRLFSFMNPLAIEIW-----IYVLIAYFLVSLCIYI 551

  Fly   359 ECKRMQKRWR------LDYLP-----SLLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISF 412
            ..|.....|:      |:.:.     ||..:|..:.|....||..:.||:...|:|.......|.
  Fly   552 VGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSL 616

  Fly   413 IMYNYYTSVVVSSLLSSPVKSKIKTMRQLA-ESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKI 476
            |:...||:.:.:.|.:..:.:.|:....|| ::.::.|......|.::...|.: |.:..|.|.:
  Fly   617 IIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRDSVI-ETYKKIWRSM 680

  Fly   477 ESQTQNPELWLPA-EQGVLRVRDNPG-YVYVFETSSGYAYVERYFTAQEICDLNEV--------- 530
            ::  :.|..:... |.|:.||  |.| |.::.| |:...|:     .|..|:|.::
  Fly   681 DN--KKPSAFTTTYEDGIKRV--NQGNYAFLME-STMLDYI-----VQRDCNLTQIGGLLDTKGY 735

  Fly   531 -LFRPEQLFYTHLHRNSTYKELFRLRFLRILETG----VYRKQRSYWVHMKLHCVAQNF-----V 585
             :..|         :.|.:::...|..|.:.|.|    :|.|   :|.:....|..:|.     .
  Fly   736 GIATP---------KGSPWRDKISLAILELQERGDIQMLYDK---WWKNTDETCTRKNTSKQSKA 788

  Fly   586 ITVGMEYVAPLLLMLICADILVVVILLVELAWKRF 620
            .::|:|.:..:.::||...|:..|:...|. |..|
  Fly   789 NSLGLESIGGVFVVLIAGIIVAAVVAFFEF-WYNF 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	61/299 (20%)
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377	52/282 (18%)
		ANF_receptor	39..371	CDD:279440	49/265 (18%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	76/399 (19%)
		Lig_chan	533..807	CDD:278489	61/301 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462802
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840