Protein Alignment Ir75a and gria4a

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_999971.1
• Gene: gria4a / 407735
• ZFINID: ZDB-GENE-020125-7
• Length: 898
• Species: Danio rerio
• Alignment Length: 497
• Identity: 98/497 - (19%)
• Similarity: 184/497 - (37%)
• Gaps: 95/497 - (19%)

  Fly   195 YGNREQLTDVVLRVAT---------------VVTQRPLTLSDDELIRFLSQENDTHI-------- 236
            ||.|...|..|..:.:               |:.|..|::.:|.     :.||.|.|
Zfish   361 YGRRVNYTMDVFELKSNGPRKIGYWNDLDKLVLVQNELSMGNDS-----AMENRTVIVTTIMEGP 420

  Fly   237 -----------DSLARF-GFHLTLILRDLLHCKMKF----IFSDSWSKSD----VVGGSVGAVVD 281
                       :...:| |:.:.|......|..:|:    :....:...|    :..|.||.:|.
Zfish   421 YVMLKKNWEMYEGNEQFEGYCVDLASEVAKHIGIKYKISIVLDGKYGARDPETKIWNGMVGELVY 485

  Fly   282 QTADLTATP---SLATEGRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFGG 343
            ..|::...|   :|..|..:.:....:..|.  |:.| :.|..:......||.|.:..:|...
Zfish   486 GKAEIAVAPLAITLVREEVIDFSKPFMSLGI--SIMI-KKPQKSKPGVFSFLDPLAYEIWMCI-- 545

  Fly   344 VLSLIGVLLWITFYMECKRMQKRWRL-------DYLPS--------LLSTFLISFGAACIQSSSL 393
            |.:.|||.  :..::..:.....|..       |..||        :.::...|.||...|....
Zfish   546 VFAYIGVS--VVLFLVSRFSPYEWHTEEPEEGSDGPPSDQPPNEFGIFNSLWFSLGAFMQQGCDF 608

  Fly   394 IPRSAGGRLIYFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLA-ESSLTVGLEPLPFTK 457
            .|||..||::....:..:.|:.:.||:.:.:.|....:.|.|::...|| ::.:..|......||
Zfish   609 TPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTK 673

  Fly   458 SYLNYSRLPEIHLFIKRKIESQTQNPE---LWLPAEQGVLRVRDNPG-YVYVFETSSGYAYVERY 518
            .:...|::.     :..|:.|..::.|   ......:||.|||.:.| |.::.|::     :..|
Zfish   674 EFFRRSKIA-----VYEKMWSYMKSAEPTVFTKTTAEGVARVRKSKGKYAFLLEST-----MNEY 728

  Fly   519 FTAQEICDLNEVLFRPEQLFY-THLHRNSTYKELFRLRFLRILETGVYRKQRSYWVHMKLHCVAQ 582
            ...::.||..:|....:...| ....:.|.......|..|::.|.||..|.::.|.:.|..|..:
Zfish   729 TEQRKPCDTMKVGGNLDSKGYGVATPKGSQLGTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPK 793

  Fly   583 N------FVITVGMEYVAPLLLMLICADILVVVILLVELAWK 618
            :      ....:.:..||.:..:|:....|.:::.|||..:|
Zfish   794 DSGSKDKSSQALSLSNVAGVFYILVGGLGLAMLVALVEFCYK 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	59/292 (20%)
gria4a	NP_999971.1	PBP1_iGluR_AMPA_GluR4	23..393	CDD:107383	5/31 (16%)
		ANF_receptor	34..375	CDD:279440	5/13 (38%)
		PBP2_iGluR_AMPA_GluR4	408..790	CDD:270445	79/398 (20%)
		Lig_chan	540..821	CDD:278489	59/294 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591219
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940