Protein Alignment Ir75a and Ir40a

DIOPT Version :10

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Alignment Length: 804
• Identity: 122/804 - (15%)
• Similarity: 248/804 - (30%)
• Gaps: 326/804 - (40%)

  Fly    44 IHPILVYHQFVQMRGVLNWSHLELSYMGHTQ------------------------PTLAIYVDIK 84
            :|..|.......:.|:||  ...|:::|:.:                        |:||: .|..
  Fly     1 MHKFLALGLLPYLLGLLN--STRLTFIGNDESDTAIALTQIVRGLQQSSLAILALPSLAL-SDGV 62

  Fly    85 CDQTQDLLEEASREQIYNQHYHWLLVGNQSKLEFYDLFGLFNISIDADVSYVKEQIQDNNDSVAY 149
            |.:.:::..:...::::..:|. .:|.:|::|.|               .:::|.:|..|:.::.
  Fly    63 CQKERNVYLDDFLQRLHRSNYK-SVVFSQTELFF---------------QHIEENLQGANECISL 111

  Fly   150 ----------AVHDVYNNGKIIGGQLNVTGSHEMSCDPFVCRRTRHLSSLQKRSKYGNREQLTDV 204
                      ::||     :.:|        |.:|...|.               :|.|...:..
  Fly   112 ILDEPNQLLNSLHD-----RHLG--------HRLSLFIFY---------------WGARWPPSSR 148

  Fly   205 VLRV-----ATVVTQ-------------RPLTLSDDELIRFLSQEN---------DTHIDSLARF 242
            |:|.     ..|||:             ||.:.|..:|:.:...:|         .|.:...|.|
  Fly   149 VIRFREPLRVVVVTRPRKKAFRIYYNQARPCSDSQLQLVNWYDGDNLGLQRIPLLPTALSVYANF 213

  Fly   243 G--------FH----------------------------------------LTLILRDLLHCKMK 259
            .        ||                                        |.::|...::.:.|
  Fly   214 KGRTFRVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFK 278

  Fly   260 FI-----------FSDSWSKSDVVGGSVGAVVDQTAD-LTATPSLATEGRLKYLSAIIETGFF-- 310
            :|           ..|....:|...|.:|.:....|| ......|:.|.|     ..||..||
  Fly   279 YIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERR-----KAIEFSFFTL 338

  Fly   311 --RSVCIFRTPH--NAGLRGDVFLQPFSPLVW-----------YLFGGVLSLIGVLLWITFYMEC 360
              ........|.  |..|   ..::||...:|           .:|.|:::|  ..:|
  Fly   339 ADSGAFATHAPRRLNEAL---AIMRPFKQDIWPHLILTIIFSGPIFYGIIAL--PYIW------- 391

  Fly   361 KRMQKRW-------------RLDYLPSLLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLI-- 410
               ::||             .:.||.. ::..|:......:.|:..:|.....:.|:|.|.|.
  Fly   392 ---RRRWANSDVEHLGELYIHMTYLKE-ITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLK 452

  Fly   411 -----------------------SFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAESSLTVGLEP 452
                                   ::::.:.|::.:.|.......:..|.|:::|..:.:..|
  Fly   453 QSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDG--- 514

  Fly   453 LPFTKSYLNYSRLPEIHLFIKRK------IESQTQ-NPELWLPAEQGVLRVRDNPGYVYVFETSS 510
                           ..|:::::      :|:.|: ..:|:....|.|  :.|..|: ::....:
  Fly   515 ---------------YRLYVEKESSSLEMLENGTELFRQLYALMRQQV--INDPQGF-FIDSVEA 561

  Fly   511 GYAYVER--------------YFTAQEICDLNEVLFRPEQLFYTHLHR-------------NSTY 548
            |...:..              :|..|:....|   |:..|..||....             |:..
  Fly   562 GIKLIAEGGEDKAVLGGRETLFFNVQQYGSNN---FQLSQKLYTRYSAVAVQIGCPFLGSLNNVL 623

  Fly   549 KELFRLRFLRILETGVYRKQ-------RSY-----WVHMKLHCVAQNFVITVGMEYVAPLLLMLI 601
            .:||....|..:....|.||       |.|     ..:.:.:...:::..||    ::||.|.::
  Fly   624 MQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTV----ISPLNLRML 684

  Fly   602 CADILVV--------VILLVELAW 617
            ....:.:        ||||:|:.:
  Fly   685 QGAFIALGVGSLAAGVILLLEIVF 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Periplasmic_Binding_Protein_Type_2	455..572	CDD:473866	25/162 (15%)
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	15/75 (20%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	21/103 (20%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	24/164 (15%)