Protein Alignment Ir75a and Ir25a

DIOPT Version :10

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Alignment Length: 668
• Identity: 126/668 - (18%)
• Similarity: 211/668 - (31%)
• Gaps: 250/668 - (37%)

  Fly    40 FMKPIHPILVYHQFVQMRGVLNWSHLELSYMGHTQPTL--AIYVD-------------------- 82
            ||||    :.|.|:....|:     |..:|..:.:|.|  |.|.|
  Fly   282 FMKP----MAYTQYRDRLGL-----LRTTYNLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPK 337

  Fly    83 ----IKCDQTQDLLEEASREQIYNQHYHWLLVGN--QSKLEFYDLF---------GLFNISIDAD 132
                :.||..|.                    ||  |..|:..|.|         |.|::...:.
  Fly   338 DMEYLNCDDFQG--------------------GNTPQRNLDLRDYFTKITEPTSYGTFDLVTQST 382

  Fly   133 V-----SYVKEQIQDN------NDSVAYAVHDVYNNGKIIGGQLNVTGSHEMSCDPFVCRRTRHL 186
            .     |::|.::..|      ..||         |.|.||                     :.:
  Fly   383 QPFNGHSFMKFEMDINVLQIRGGSSV---------NSKSIG---------------------KWI 417

  Fly   187 SSLQKRSKYGNREQL----TDVVLRVATVVTQRPLTLSDD-----------ELIRFLSQENDTHI 236
            |.|.......:.||:    .|.|.|:.||| |.|..:.|:           :||        ..|
  Fly   418 SGLNSELIVKDEEQMKNLTADTVYRIFTVV-QAPFIMRDETAPKGYKGYCIDLI--------NEI 473

  Fly   237 DSLARFGFHLTLILRDLLHCKMKFIFSD---SWSKSDVVGGSVGAVVDQTADLTATPSLATEGRL 298
            .::..|.:.:..:...      ||...|   .|:      |.|..::|:.||:          .|
  Fly   474 AAIVHFDYTIQEVEDG------KFGNMDENGQWN------GIVKKLMDKQADI----------GL 516

  Fly   299 KYLSAIIETGFFRSVCI-FRTPHNAGLRGDVFLQ-PFSPL------------VWYLFGGVLSLIG 349
            ..:|.:.|    |.:.| |..|:...:...:.:| |.||.            ||...........
  Fly   517 GSMSVMAE----REIVIDFTVPYYDLVGITIMMQRPSSPSSLFKFLTVLETNVWLCILAAYFFTS 577

  Fly   350 VLLWITFYMECKRMQKRW--------RLDYLP-------SLLSTFLISFGAACIQSSSLIPRSAG 399
            .|:||.         .||        |..|..       :|.........:...|.....|::..
  Fly   578 FLMWIF---------DRWSPYSYQNNREKYKDDEEKREFNLKECLWFCMTSLTPQGGGEAPKNLS 633

  Fly   400 GRLIYFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAESSLTVGLEPLPFTKSYLNYSR 464
            |||:....:|..||:...||:.:.:.|..|.:.:.::::..||: ...:...||..:.:...:.|
  Fly   634 GRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAK-QYKILYAPLNGSSAMTYFER 697

  Fly   465 LPEI-HLF---------------IKRKIESQTQNP------ELW-------LPA--EQGVLRVRD 498
            :..| .:|               ::|...:....|      ::|       |||  ::.|.|||:
  Fly   698 MSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKMWQAMQEAKLPATLDEAVARVRN 762

  Fly   499 NPGYVYVFETSSGYAYVE-----RYFTAQEICDL----NEVLFRPEQLFYTHLHRNSTYKELFRL 554
            :       ..::|:|::.     ||..... |||    .|...:|   :...:.:.|..|:.|..
  Fly   763 S-------TAATGFAFLGDATDIRYLQLTN-CDLQVVGEEFSRKP---YAIAVQQGSHLKDQFNN 816

  Fly   555 RFLRILETGVYRKQRSYW 572
            ..|.:|......|.:..|
  Fly   817 AILTLLNKRQLEKLKEKW 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Periplasmic_Binding_Protein_Type_2	455..572	CDD:473866	28/156 (18%)
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	34/194 (18%)
		PBP2_iGluR_putative	438..836	CDD:270435	88/453 (19%)