Protein Alignment Ir75a and GluRIIC

DIOPT Version :10

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Alignment Length: 664
• Identity: 135/664 - (20%)
• Similarity: 249/664 - (37%)
• Gaps: 185/664 - (27%)

  Fly    44 IHPILVYHQFVQMRGVLNWSHLELSYMGHTQPTLAIYVDIKCDQTQDLLEEASREQIYNQHYHWL 108
            ||.::  |..:|: ...:|.:....|     |...:...|.|    |......|.....::...|
  Fly   306 IHDLI--HDALQL-FAQSWRNASFFY-----PDRMVVPRITC----DFAASGGRTWAMGRYLARL 358

  Fly   109 LVGNQ---------SKLEFYDLFG---LFNISIDADVSYVKEQIQDNNDSVAYAVHDVYNNGKII 161
            :.|..         |.|:| |..|   .|||           ::.|..|.:..|:.|  ..|:|.
  Fly   359 MKGTSGVNNTNFRTSILQF-DEDGQRITFNI-----------EVYDPLDGIGIAIWD--PRGQIT 409

  Fly   162 GGQLNVTGSHEMSCDPFVCRRTRHLSSLQKRSKYGNREQLTDVVLRVATVV---------TQRPL 217
              ||||.                  ...||:           ::.||||.:         |.|.|
  Fly   410 --QLNVD------------------VKAQKK-----------MIYRVATRIGPPYFSYNETAREL 443

  Fly   218 TLSDDELIRFLSQENDTHIDSLARFGFHLTLILRDLLHCKMKFIF----SDSWSKSDVV----GG 274
            .|:.:.|.:..:.:   .||::||             |...:::|    ...:.|.|..    .|
  Fly   444 NLTGNALYQGYAVD---LIDAIAR-------------HVGFEYVFVPVADQQYGKLDKETKQWNG 492

  Fly   275 SVGAVVDQTA-----DLTATPSLATEGRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFS 334
            .:|.:::..|     |||.|.:..|  .:.:....::.|.  |:..:::|| .....|.:|.||.
  Fly   493 IIGEIINNDAHMGICDLTITQARKT--AVDFTVPFMQLGV--SILAYKSPH-VEKTLDAYLAPFG 552

  Fly   335 PLVWYLFGGVLSLIGVLLWITFYM---------------ECKR----MQKRWRLDYLPSLLSTFL 380
            ..||     :..||.|.: :||..               .|.|    ::.:||:.      :|..
  Fly   553 GEVW-----IWILISVFV-MTFLKTIVARISKMDWENPHPCNRDPEVLENQWRIH------NTGW 605

  Fly   381 ISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAESS 445
            ::..:.......::|||...|:.....::.:.|:.|.||:.:.:.|.||.::..|..::.|:..
  Fly   606 LTVASIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQ- 669

  Fly   446 LTVGLEPLPFTKSY--LNYSRLPEIHLFIKRKIESQTQNPELWLPAE------QGVLRVRDNPG- 501
                 :.:.|...|  ..|:.|.:.:..:.|...:...|.:   |:.      :||.|||.|.|
  Fly   670 -----KKVKFGTIYGGSTYNLLADSNETVYRLAFNLMNNDD---PSAYTKDNLEGVDRVRKNRGD 726

  Fly   502 YVYVFETSSGYAYVERYFTAQEICDLNEVLFR-PEQLFYTHLHRNSTYKELFRLRFLRILETG-V 564
            |:::.||::    :|  :..::.|||..|..: .|:.:...:...:.|:....:..|::.|.| :
  Fly   727 YMFLMETTT----LE--YHREQNCDLRSVGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSERGEL 785

  Fly   565 YRKQRSYWVHMKLHCVAQ---------NFVITVGMEYV--APLLLMLI--CADILVVV--ILLVE 614
            |..::.:|.:....|..:         .|....|:.|.  |.:|:..:  ..:.||.|  :.|.|
  Fly   786 YDLKQKWWKNPNASCFEEPDPDATPDMTFEELRGIFYTLYAGILIAFLIGITEFLVYVQQVALEE 850

  Fly   615 -LAWKRFFTRHLTF 627
             |.:|..|.:.:.|
  Fly   851 RLTFKDAFKKEIRF 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Periplasmic_Binding_Protein_Type_2	455..572	CDD:473866	28/127 (22%)
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	26/128 (20%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	86/418 (21%)
		Lig_chan	554..827	CDD:459656	58/299 (19%)