Protein Alignment Ir75a and Nmdar2

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Alignment Length: 657
• Identity: 126/657 - (19%)
• Similarity: 220/657 - (33%)
• Gaps: 204/657 - (31%)

  Fly    50 YHQFVQMRGVLNWSHLELSYMGHTQPTLAIYVDIKCDQTQDLLEEASREQIYNQHYHWLLVG--- 111
            |.:.|.:.|.||..::|.:..|          |::   :.:|.....|....|::..|..:|
  Fly   423 YLRNVSIEGDLNKPNIEFTADG----------DLR---SAELKIMNLRPSANNKNLVWEEIGVWK 474

  Fly   112 --NQSKLEFYDL----------------FGLFNISIDADVSYVKEQIQDNNDSVAYAVHDVYNNG 158
              ...||:..|:                |.| .|:...:..|:       |.|.|..|     :|
  Fly   475 SWETQKLDIRDIAWPGNSHAPPQGVPEKFHL-KITFLEEAPYI-------NLSPADPV-----SG 526

  Fly   159 KII---GGQLNVTGSHEMSCDPFVCRRTRHLSSLQKRSKYGNREQLTDVVLRVATVVTQRPLTLS 220
            |.:   |....|...|||:.|..|.:..|:.|..|..|.:
  Fly   527 KCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGF------------------------- 566

  Fly   221 DDELIRFLSQENDTHIDSLARF----GFHLTLI-LRDLLHCKMKFIFSDSWSKSDVVGGSVGAVV 280
                          .||.|.:|    ||...|: :.|   .|...:.:..|:      |.:..:|
  Fly   567 --------------CIDLLEKFAEELGFTYELVRVED---GKWGTLENGKWN------GLIADLV 608

  Fly   281 DQTADLTATPSLAT---EGRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFG 342
            ::..|:..|..:..   |..:.:....:|||    :.|........:....||:||....|.|.|
  Fly   609 NRKTDMVLTSLMINTEREAVVDFSEPFMETG----IAIVVAKRTGIISPTAFLEPFDTASWMLVG 669

  Fly   343 -----GVLSLIGVLLWIT-------FYMECKRMQKRWRLDYLPSLLSTF----LISFGAACIQSS 391
                 ....:|.:..|::       .|::...:     ..|..||..|:    .:.|.||....|
  Fly   670 IVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNV-----TPYRFSLFRTYWLVWAVLFQAAVHVDS 729

  Fly   392 SLIPRSAGGRLI--YFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAES---------- 444
               ||....|.:  .:|||.:.|:.  .||:.:.:.:::   :.:......|.:|
  Fly   730 ---PRGFTSRFMTNVWALFAVVFLA--IYTANLAAFMIT---REEFHEFSGLNDSRLVHPFSHKP 786

  Fly   445 SLTVGLEPLPFTKS----YLNYSRLPEIHLFIKRKIESQTQNPELWLPAEQGVLRVRDNPGYVYV 505
            |...|..|...|.|    |.|.     :|.::::..::...:         ||..|.:.....::
  Fly   787 SFKFGTIPYSHTDSTIHKYFNV-----MHNYMRQYNKTSVAD---------GVAAVLNGNLDSFI 837

  Fly   506 FETSSGYAYVERYFTAQ-EICDLNEVLFRPEQLFYT------HLHRNSTYKELFRLRFLRILETG 563
            ::.:     |..|..|| |.|.|..|     ..:|.      ...|||.|.::|..|.|.....|
  Fly   838 YDGT-----VLDYLVAQDEDCRLMTV-----GSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANG 892

  Fly   564 VYRKQRSYWV----------HMKLHCVAQNFVITVGMEYVAPLLLMLICADILVVVILLVELAWK 618
            ...:.|.||:          |.....:|        :|......|:|:...:|..::||:|..:.
  Fly   893 DLERLRRYWMTGTCRPGKQEHKSSDPLA--------LEQFLSAFLLLMAGILLAALLLLLEHVYF 949

  Fly   619 RFFTRHL 625
            ::..:.|
  Fly   950 KYIRKRL 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	61/314 (19%)
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	16/79 (20%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	100/507 (20%)
		Lig_chan	665..928	CDD:278489	59/307 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462783
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840