Protein Alignment Ir75a and Gria4

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001106655.1
• Gene: Gria4 / 29629
• RGDID: 61863
• Length: 902
• Species: Rattus norvegicus
• Alignment Length: 533
• Identity: 103/533 - (19%)
• Similarity: 210/533 - (39%)
• Gaps: 79/533 - (14%)

  Fly   129 IDADVSYVKEQIQDNNDSVAYAVHDVYNNGKIIGGQLNVTGSHEMSCDPFVCRRT---------- 183
            ||.:.:..:.:||....:|.:   |.|      |.::|.|      .|.|..:.|
  Rat   343 IDMERTLKQVRIQGLTGNVQF---DHY------GRRVNYT------MDVFELKSTGPRKVGYWND 392

  Fly   184 -RHLSSLQKRSKYGNREQLTDVVLRVATVVTQRPLTL--SDDELIRFLSQENDTH----IDSLAR 241
             ..|..:|.....||.....:....|.|.:.:.|..:  .:.|:.    :.||.:    :|..:.
  Rat   393 MDKLVLIQDMPTLGNDTAAIENRTVVVTTIMESPYVMYKKNHEMF----EGNDKYEGYCVDLASE 453

  Fly   242 FGFHLTLILRDLLHCKMKFIFSDSWSKSDVVGGSVGAVVDQTADLTATP---SLATEGRLKYLSA 303
            ...|:.:..:..:....|:...|:.:|  :..|.||.:|...|::...|   :|..|..:.:...
  Rat   454 IAKHIGIKYKIAIVPDGKYGARDADTK--IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKP 516

  Fly   304 IIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFGGVLSLIGVLLWITFYMECKRMQKRWR 368
            .:..|.  |:.| :.|..:......||.|.:..:|...  |.:.|||.  :..::..:.....|.
  Rat   517 FMSLGI--SIMI-KKPQKSKPGVFSFLDPLAYEIWMCI--VFAYIGVS--VVLFLVSRFSPYEWH 574

  Fly   369 L-----------DYLPS---LLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYT 419
            .           |..|:   :.::...|.||...|...:.|||..||::....:..:.|:.:.||
  Rat   575 TEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYT 639

  Fly   420 SVVVSSLLSSPVKSKIKTMRQLA-ESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIESQTQNP 483
            :.:.:.|....:.|.|::...|| ::.:..|......||.:...|:   |.::.|.....::..|
  Rat   640 ANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSK---IAVYEKMWTYMRSAEP 701

  Fly   484 ELWL-PAEQGVLRVRDNPG-YVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFY-THLHRN 545
            .::. ...:||.|||.:.| :.::.|::     :..|...::.||..:|....:...| ....:.
  Rat   702 SVFTRTTAEGVARVRKSKGKFAFLLEST-----MNEYIEQRKPCDTMKVGGNLDSKGYGVATPKG 761

  Fly   546 STYKELFRLRFLRILETGVYRKQRSYWVHMKLHC-----VAQNFVITVGMEYVAPLLLMLICADI 605
            |:.:....|..|::.|.|:..|.::.|.:.|..|     .:::....:.:..||.:..:|:....
  Rat   762 SSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLG 826

  Fly   606 LVVVILLVELAWK 618
            |.:::.|:|..:|
  Rat   827 LAMLVALIEFCYK 839

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	56/288 (19%)
Gria4	NP_001106655.1	PBP1_iGluR_AMPA_GluR4	28..398	CDD:107383	14/69 (20%)
		ANF_receptor	39..380	CDD:279440	12/51 (24%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	78/401 (19%)
		Lig_chan	546..825	CDD:278489	56/290 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349828
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840