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Protein Alignment Ir75a and Gria2

DIOPT Version :9

Sequence 1:	NP_649012.2	Gene:	Ir75a / 39982	FlyBaseID:	FBgn0036757	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	641	Identity:	123/641 - (19%)
Similarity:	234/641 - (36%)	Gaps:	133/641 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 ILVYHQFVQMRGVLNWSHL-ELSYMGHTQPTLAIYVDIKCDQTQDLLE----------EASR--- 97
            |:.|...:..:.:..||.| |..|.|....|:.....:..|..|.:.|          |.||
  Rat   262 IVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGN 326

  Fly    98 --EQIYNQHYHWLLVGNQSKLEFYDLFGLFNISIDADVSYVKEQIQDNNDSVAYAVHDVYNNGKI 160
              :.:.|....|                  ...::.:.:..:.|::..:.::.:.     .|||.
  Rat   327 AGDCLANPAVPW------------------GQGVEIERALKQVQVEGLSGNIKFD-----QNGKR 368

  Fly   161 IGGQLNV-----TGSHEMSCDPFVCRRTRHLSSLQKRSKYGNREQLTDVVLRVATVVTQRPLTLS 220
            |...:|:     .|..::.....|.:....|:.|...:.....|..|.||    |.:.:.|..
  Rat   369 INYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVV----TTILESPYV-- 427

  Fly   221 DDELIRFLSQENDTHIDSLARF-GFHLTLILRDLLHCKMKFIFSDSWSKSDVVG----------- 273
                   :.::|...::...|: |:.:.|......||..|:       |..:||
  Rat   428 -------MMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKY-------KLTIVGDGKYGARDADT 478

  Fly   274 ----GSVGAVVDQTADLTATP---SLATEGRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQ 331
                |.||.:|...||:...|   :|..|..:.:....:..|.  |:.| :.|..:......||.
  Rat   479 KIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGI--SIMI-KKPQKSKPGVFSFLD 540

  Fly   332 PFSPLVWYLFGGVLSLIGVLLWITFYMECKRMQKRWRLDYLP--------------SLLSTFLIS 382
            |.:..:|...  |.:.|||.  :..::..:.....|..:...              .:.::...|
  Rat   541 PLAYEIWMCI--VFAYIGVS--VVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFS 601

  Fly   383 FGAACIQSSSLIPRSAGGRLI-----YFALFLISFIMYNYYTSVVVSSLLSSPVKS--KIKTMRQ 440
            .||...|...:.|||..||::     :|.|.:||....|....:.|..:: ||::|  .:....:
  Rat   602 LGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV-SPIESAEDLSKQTE 665

  Fly   441 LAESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIESQTQNPELWL-PAEQGVLRVRDNPG-YV 503
            :|..:|..|     .||.:...|:   |.:|.|.....::..|.::: ...:||.|||.:.| |.
  Rat   666 IAYGTLDSG-----STKEFFRRSK---IAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722

  Fly   504 YVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFY-THLHRNSTYKELFRLRFLRILETGVYRK 567
            |:.|::     :..|...::.||..:|....:...| ....:.|:......|..|::.|.|:..|
  Rat   723 YLLEST-----MNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDK 782

  Fly   568 QRSYWVHMKLHC-----VAQNFVITVGMEYVAPLLLMLICADILVVVILLVELAWK 618
            .::.|.:.|..|     .::.....:.:..||.:..:|:....|.:::.|:|..:|
  Rat   783 LKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYK 838

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.