Protein Alignment Ir75a and GRID2

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_011530195.2
• Gene: GRID2 / 2895
• HGNCID: 4576
• Length: 1035
• Species: Homo sapiens
• Alignment Length: 495
• Identity: 94/495 - (18%)
• Similarity: 196/495 - (39%)
• Gaps: 132/495 - (26%)

  Fly   196 GNREQLTD---------VVLRVATVVTQRPLTLSDDELI----RFLSQENDTHIDSLARF-GFHL 246
            |....|||         |||||.||: :.|..:..:.::    ::.....|. :|:|:.: ||:.
Human   452 GLNGSLTDKKLENNMRGVVLRVVTVL-EEPFVMVSENVLGKPKKYQGFSIDV-LDALSNYLGFNY 514

  Fly   247 TLILRDLLHCKMKFIFSD----------SWSKSDVVGGSVGAVVDQTAD-----LTATPSLATEG 296
            .:           ::..|          :|:      |.||.:|.:.||     ||.||.  .|.
Human   515 EI-----------YVAPDHKYGSPQEDGTWN------GLVGELVFKRADIGISALTITPD--REN 560

  Fly   297 RLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVF--LQPFSPLVWYLFGGVLSLIGVLLWITFYME 359
            .:.:.:..::  :...|.:.|.....    |:|  |.||...:|....|.:.|:|:|:::..::.
Human   561 VVDFTTRYMD--YSVGVLLRRAEKTV----DMFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLN 619

  Fly   360 CKRMQKRWRLDYLPSLLSTFLIS-----FGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYT 419
            ..|:|       :.|:.||.|.:     :|:...|...:...:...|::..|.:|.:.|:.:.||
Human   620 PPRLQ-------MGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYT 677

  Fly   420 SVVVSSLLSSPVKSKIKTMRQLAESSLTVGLEPLPF----TKSYLNYSRLPEIHLFIKRKIESQT 480
            :.:.:.|..:.::|.|::::.|::.:      .:|:    ..:...:.|:..::.|.:..:.||
Human   678 ANLAAFLTITRIESSIQSLQDLSKQT------EIPYGTVLDSAVYEHVRMKGLNPFERDSMYSQ- 735

  Fly   481 QNPELW-------------LPAEQGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEVLF 532
                :|             |.::.|:.:|:.. .|.:|::.:           ..|...:|:
Human   736 ----MWRMINRSNGSENNVLESQAGIQKVKYG-NYAFVWDAA-----------VLEYVAIND--- 781

  Fly   533 RPEQLFYT------------HLHRNSTYKELFRLRFLRILETGVYRKQRSYWVHMKLHCVAQNFV 585
             |:..|||            .|...|.|:::|..|.|.:.:.|.....:..|......|...:.|
Human   782 -PDCSFYTIGNTVADRGYGIALQHGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQCDLYSSV 845

  Fly   586 IT------VGMEYVAPLLLMLICADILVVVILLVELAWKR 619
            .|      :.::..|.:..:|....:|...|.::|..|.:
Human   846 DTKQKGGALDIKSFAGVFCILAAGIVLSCFIAMLETWWNK 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	53/305 (17%)
GRID2	XP_011530195.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155902
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740