Protein Alignment Ir75a and Grik5

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_006228444.1
• Gene: Grik5 / 24407
• RGDID: 2735
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 692
• Identity: 127/692 - (18%)
• Similarity: 233/692 - (33%)
• Gaps: 229/692 - (33%)

  Fly    79 IYVDIKCDQTQDLLEEASREQIYNQHYHWLLVGNQSKLEFYDL--------------FGLFNISI 129
            |.:|.....:..:|.:||...:.:..|.::|    :.::|..|              |.:||.|.
  Rat   214 IIIDANASISHLVLRKASELGMTSAFYKYIL----TTMDFPILHLDGIVEDSSNILGFSMFNTSH 274

  Fly   130 DADVSYVKE---QIQDNNDSVAY------------AVHDVYNNGKIIGGQLNVTGSHEMSCDPFV 179
            .....:|:.   ..::|.::..|            |||      .::.....:..|.|:...|..
  Rat   275 PFYPEFVRSLNMSWRENCEASTYPGPALSAALMFDAVH------VVVSAVRELNRSQEIGVKPLA 333

  Fly   180 C----------------------------------RRTRHLSSLQKRSKYGNRE----------- 199
            |                                  :||.:...:.::|:.|:||
  Rat   334 CTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLA 398

  Fly   200 ------------QLTDVVLRVATV-----VTQRP--LTLSDDELIRFLSQENDTHIDSLARFGFH 245
                        .|.:..|.|.|:     |.:||  ..||.:|.......:....:..|.||.:.
  Rat   399 MNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYR 463

  Fly   246 LTLILRDLLHCKMKFIFSDSWSKSDVVGGSVGAVVD-QTADLTATPSLATEGRLKYLS------- 302
            |.|:...|......   :.||:      |.||.::: |.|||.......|..|.|.:.
  Rat   464 LRLVEDGLYGAPEP---NGSWT------GMVGELINRQKADLAVAAFTITAEREKVIDFSKPFMT 519

  Fly   303 ---AII-------ETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVW-YLFGGVLSLIGVLLWITF 356
               :|:       :.|:|.                 ||.||||.|| ::....|::..||
  Rat   520 LGISILYRVHMGRKPGYFS-----------------FLDPFSPAVWLFMLLAYLAVSCVL----- 562

  Fly   357 YMECKRMQKRWRLDYLP---------------SLLSTFLISFGAACIQSSSLIPRSAGGRLIYFA 406
            ::..:.....|   |.|               :|.::.....|....|.|.::||:...|.:...
  Rat   563 FLAARLSPYEW---YNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGV 624

  Fly   407 LFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAE------SSLTVGLEPLPFTKS-YLNYSR 464
            .:..:.|:.:.||:.:.:.|....::..:::...||:      .::..|.....|..| |..|.|
  Rat   625 WWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQR 689

  Fly   465 LPEIHLFIKRKIESQTQNPELWLPA-EQGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLN 528
            :...         .|::.|.:::.: |:|:.||. |..|.::.|::.. .|..|.     .|:|.
  Rat   690 MWNY---------MQSKQPSVFVKSTEEGIARVL-NSRYAFLLESTMN-EYHRRL-----NCNLT 738

  Fly   529 EV-----------------LFRPE-QLFYTHLHRNSTYKELFRLRFLRILETGVYRKQRSYWVHM 575
            ::                 .||.| .|....|..|:      ||..|:          |.:|...
  Rat   739 QIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENN------RLEILK----------RKWWEGG 787

  Fly   576 KLHCVAQNFVITVGMEYVAPLLLMLICADILVVVILLVELAW 617
            :......:....:|||.:..:.::|||..|:.|.:.::|..|
  Rat   788 RCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFIW 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	56/307 (18%)
Grik5	XP_006228444.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616	29/196 (15%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:389745	86/436 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349846
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740