Protein Alignment Ir75a and Grik5

DIOPT Version :10

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_030098003.1
• Gene: Grik5 / 14809
• MGIID: 95818
• Length: 1003
• Species: Mus musculus
• Alignment Length: 635
• Identity: 118/635 - (18%)
• Similarity: 213/635 - (33%)
• Gaps: 211/635 - (33%)

  Fly   122 FGLFNISIDADVSYVKE---QIQDNNDSVAY------------AVHDVYNNGKIIGGQLNVTGSH 171
            |.:||.|......:|:.   ..::|.::..|            |||      .::.....:..|.
Mouse   290 FSMFNTSHPFYPEFVRSLNMSWRENCEASTYPGPALSAALMFDAVH------VVVSAVRELNRSQ 348

  Fly   172 EMSCDPFVC----------------------------------RRTRHLSSLQKRSKYGNRE--- 199
            |:...|..|                                  :||.:...:.::|:.|:||
Mouse   349 EIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGV 413

  Fly   200 --------------------QLTDVVLRVATV-----VTQRP--LTLSDDELIRFLSQENDTHID 237
                                .|.:..|.|.|:     |.:||  ..||.:|.......:....:.
Mouse   414 WYSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELA 478

  Fly   238 SLARFGFHLTLILRDLLHCKMKFIFSDSWSKSDVVGGSVGAVVD-QTADLTATPSLATEGRLKYL 301
            .|.||.:.|.|:...|......   :.||:      |.||.::: |.|||.......|..|.|.:
Mouse   479 ELLRFRYRLRLVEDGLYGAPEP---NGSWT------GMVGELINRQKADLAVAAFTITAEREKVI 534

  Fly   302 S----------AII-------ETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVW-YLFGGVLSLI 348
            .          :|:       :.|:|.                 ||.||||.|| ::....|::.
Mouse   535 DFSKPFMTLGISILYRVHMGRKPGYFS-----------------FLDPFSPAVWLFMLLAYLAVS 582

  Fly   349 GVLLWITFYMECKRMQKRWRLDYLP---------------SLLSTFLISFGAACIQSSSLIPRSA 398
            .||     ::..:.....|   |.|               :|.::.....|....|.|.::||:.
Mouse   583 CVL-----FLAARLSPYEW---YNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRAL 639

  Fly   399 GGRLIYFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAE------SSLTVGLEPLPFTK 457
            ..|.:....:..:.|:.:.||:.:.:.|....::..:::...||:      .::..|.....|..
Mouse   640 STRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQN 704

  Fly   458 S-YLNYSRLPEIHLFIKRKIESQTQNPELWLPA-EQGVLRVRDNPGYVYVFETSSGYAYVERYFT 520
            | |..|.|:...         .|::.|.:::.: |:|:.||. |..|.::.|::.. .|..|.
Mouse   705 SRYQTYQRMWNY---------MQSKQPSVFVKSTEEGIARVL-NSRYAFLLESTMN-EYHRRL-- 756

  Fly   521 AQEICDLNEV-----------------LFRPE-QLFYTHLHRNSTYKELFRLRFLRILETGVYRK 567
               .|:|.::                 .||.| .|....|..|:      ||..|:
Mouse   757 ---NCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENN------RLEILK--------- 803

  Fly   568 QRSYWVHMKLHCVAQNFVITVGMEYVAPLLLMLICADILVVVILLVELAW 617
             |.:|...:......:....:|||.:..:.::|||..|:.|.:.::|..|
Mouse   804 -RKWWEGGRCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFIW 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Periplasmic_Binding_Protein_Type_2	455..572	CDD:473866	28/136 (21%)
Grik5	XP_030098003.1	PBP1_iGluR_Kainate_KA1_2	23..424	CDD:380616	20/139 (14%)
		Periplasmic_Binding_Protein_Type_2	437..808	CDD:473866	86/436 (20%)