Protein Alignment Ir75a and Gria4

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_006509904.1
• Gene: Gria4 / 14802
• MGIID: 95811
• Length: 912
• Species: Mus musculus
• Alignment Length: 533
• Identity: 104/533 - (19%)
• Similarity: 210/533 - (39%)
• Gaps: 79/533 - (14%)

  Fly   129 IDADVSYVKEQIQDNNDSVAYAVHDVYNNGKIIGGQLNVTGSHEMSCDPFVCRRT---------- 183
            ||.:.:..:.:||....:|.:   |.|      |.::|.|      .|.|..:.|
Mouse   343 IDMERTLKQVRIQGLTGNVQF---DHY------GRRVNYT------MDVFELKSTGPRKVGYWND 392

  Fly   184 -RHLSSLQKRSKYGNREQLTDVVLRVATVVTQRPLTL--SDDELIRFLSQENDTH----IDSLAR 241
             ..|..:|.....||.....:....|.|.:.:.|..:  .:.|:.    :.||.:    :|..:.
Mouse   393 MDKLVLIQDAPTLGNDTAAIENRTVVVTTIMESPYVMYKKNHEMF----EGNDKYEGYCVDLASE 453

  Fly   242 FGFHLTLILRDLLHCKMKFIFSDSWSKSDVVGGSVGAVVDQTADLTATP---SLATEGRLKYLSA 303
            ...|:.:..:..:....|:...|:.:|  :..|.||.:|...|::...|   :|..|..:.:...
Mouse   454 IAKHIGIKYKIAIVPDGKYGARDADTK--IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKP 516

  Fly   304 IIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFGGVLSLIGVLLWITFYMECKRMQKRWR 368
            .:..|.  |:.| :.|..:......||.|.:..:|...  |.:.|||.  :..::..:.....|.
Mouse   517 FMSLGI--SIMI-KKPQKSKPGVFSFLDPLAYEIWMCI--VFAYIGVS--VVLFLVSRFSPYEWH 574

  Fly   369 L-----------DYLPS---LLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYT 419
            .           |..|:   :.::...|.||...|...:.|||..||::....:..:.|:.:.||
Mouse   575 TEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYT 639

  Fly   420 SVVVSSLLSSPVKSKIKTMRQLA-ESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIESQTQNP 483
            :.:.:.|....:.|.|::...|| ::.:..|......||.:...|:   |.::.|.....::..|
Mouse   640 ANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSK---IAVYEKMWTYMRSAEP 701

  Fly   484 ELWL-PAEQGVLRVRDNPG-YVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFY-THLHRN 545
            .::. ...:||.|||.:.| :.::.|::     :..|...::.||..:|....:...| ....:.
Mouse   702 SVFTRTTAEGVARVRKSKGKFAFLLEST-----MNEYIEQRKPCDTMKVGGNLDSKGYGVATPKG 761

  Fly   546 STYKELFRLRFLRILETGVYRKQRSYWVHMKLHC-----VAQNFVITVGMEYVAPLLLMLICADI 605
            |:.:....|..|::.|.||..|.::.|.:.|..|     .:::....:.:..||.:..:|:....
Mouse   762 SSLRTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLG 826

  Fly   606 LVVVILLVELAWK 618
            |.:::.|:|..:|
Mouse   827 LAMLVALIEFCYK 839

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	57/288 (20%)
Gria4	XP_006509904.1	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611	14/71 (20%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	79/401 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846350
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840