Protein Alignment Ir75a and LOC1281300

DIOPT Version :10

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_061504074.1
• Gene: LOC1281300 / 1281300
• VectorBaseID: AGAMI1_004328
• Length: 584
• Species: Anopheles gambiae
• Alignment Length: 653
• Identity: 148/653 - (22%)
• Similarity: 253/653 - (38%)
• Gaps: 154/653 - (23%)

  Fly     1 MQLVQLANFVLDNLVQSR----------------IGFIVLFHCWQ---SDESLKFAQQFMKPIHP 46
            |::|..|.|:|..|..:|                |..::|.||.|   ..:.::.|....:..|.
Mosquito     1 MKVVVCALFLLGLLTPTRCSSRTQLIEEFLEKRSITSLMLLHCVQEPVDQDVIRIASALRQSFHG 65

  Fly    47 ILVYHQFVQMRGVLNWSHLELSYMGHTQPTLAIYVDIKCDQTQDLLEEASREQIYNQHYHWLLVG 111
            .:.|   :.:.|.....|.:. :|.:.:...||.::::|...:.:|...|....:|..:|||:.|
Mosquito    66 SVYY---LDVTGAHFRRHFQW-HMFYERYKTAITLNLECSGMESVLSHLSDNAYFNDTFHWLMFG 126

  Fly   112 NQSKLEFYDLFGLFNISIDADVSYVKEQIQDNNDSVAYAVHDVYNNGKIIGGQLN--VTGSHEMS 174
            .::..:...|....||:.||.:..|.::....:....:.|:||....|..||:::  :.|:
Mosquito   127 GRNFEQVTCLLSAQNINYDASIMLVFDRGDRADVPRIFEVYDVRGTVKRRGGRVSFELLGT---- 187

  Fly   175 CDPFVCRRTRHLSSLQKRSKYGNR-EQLTDVVLRVATVVTQRPLTLSDDELIRFLSQENDTHIDS 238
                       :|||.:..|...| ..|..:.|..|.....:   |.....|.:|:...:
Mosquito   188 -----------VSSLNQLPKSRARSHDLEGIELWTALATIDK---LQSQSFIEYLNPRTE----- 233

  Fly   239 LARFGFHLTLILRDLLHCKMKFIFSDSWSKSDVVGGSVGAVVDQTADLTATPSLATEGRLKYLSA 303
                    ...|...|||.:                             .:|||.       ||.
Mosquito   234 --------RTSLMGTLHCTL-----------------------------LSPSLT-------LSF 254

  Fly   304 IIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVW----YLFGGVLSLIGVLLWITFYMEC--KR 362
            .:...|:   .:||.|.:.. ..::|:.||:.:||    .:||.|..||.:|:      .|  :.
Mosquito   255 CLSRSFY---TVFRHPKSLN-NSNIFMLPFTNIVWLAISLIFGAVALLIALLI------VCIHRT 309

  Fly   363 MQKRWRLDYL--PSLLSTFLISFGAACIQS--SSLIPRSAGGRLIYFALFLISFIMYNYYTSVVV 423
            .:.|..||:|  .|||.|    .|..|.|.  ..:|..|:...|:..|: ..|.|::.:|.|.:|
Mosquito   310 GRSRSTLDWLVEQSLLGT----LGMVCQQGIHHRIIWWSSNQVLVLVAM-CSSMILFQFYCSFIV 369

  Fly   424 SSLLSSPVKSKIKTMRQLAESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIESQTQNPELWLP 488
            ...|.:|.|: |.|:::|.:|.:.:.:|.|.:.:.:...:..|......:.|:          ||
Mosquito   370 GYQLITPPKT-INTLQKLVDSEIKMTVENLSYHRDFFLRTNNPAALKLYETKV----------LP 423

  Fly   489 AEQ--------GVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFYTHLHRN 545
            ...        |:..||.. ||.:..|||.|.|.:...||.:|||||.:|...|::..:..|.:.
Mosquito   424 NRYGGFVNLSFGMQLVRQG-GYAFHCETSYGNALIIETFTEREICDLQQVQLYPQRPVHLPLIKG 487

  Fly   546 STYKELFRLRFLRILETGV--YRKQRSYWVHMK-----------LHCVAQNF---VITVGMEYVA 594
            |..:|||::....|.|:|:  |...|.|....|           :|.....|   ::..||...|
Mosquito   488 SPLRELFKINLQLIKESGLLAYHHARYYTPRPKCNKQSSTHTEQIHLADVRFAFVLLAAGMAASA 552

  Fly   595 PLL 597
            .||
Mosquito   553 ALL 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Periplasmic_Binding_Protein_Type_2	455..572	CDD:473866	33/126 (26%)
LOC1281300	XP_061504074.1	None