Protein Alignment Ir75a and LOC1275780

DIOPT Version :10

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_315067.5
• Gene: LOC1275780 / 1275780
• VectorBaseID: AGAMI1_007352
• Length: 622
• Species: Anopheles gambiae
• Alignment Length: 648
• Identity: 137/648 - (21%)
• Similarity: 266/648 - (41%)
• Gaps: 123/648 - (18%)

  Fly    22 IVLFHCWQSDESLKF-----------------AQQFMKPIHPILVYHQFVQMRGVLNWSHLELSY 69
            :.:..||:::|...|                 :::.:..|||     ..|...|:|
Mosquito    25 VTVISCWEAEERYDFFLAATKKGLLVKFVDATSKEALIAIHP-----NRVSQAGLL--------- 75

  Fly    70 MGHTQPTLAIYVDIKCDQTQDLLEEASR----EQIYNQ----HYHWLLV---------------- 110
                       :|..|:     :|..|:    :|:.|:    :.|||:|
Mosquito    76 -----------IDASCE-----IEPISKLWQMDQLLNKLLYGNLHWLIVEKQLPVKRSIDSGPYS 124

  Fly   111 GNQSKLEFYDLFGLFNISIDADVSYVKEQIQDNNDSVAYAVHDVYNNGKIIGGQLNVTGSHEMSC 175
            .:|.:|.:.:.....::....:|....::|.|:.:  .:.::..|...::  ..:|:..::..:.
Mosquito   125 SDQLELLYNERLRPLDVMPYTNVVLAFQKISDSWE--LFELYKPYRKARL--SVVNIASNYLPAV 185

  Fly   176 DPFVCRRTRHLSSLQKRSK-YGNREQLTDVVLRVATVVTQRPLTLSDDELIRFLSQENDTH-IDS 238
            |       |:.|.|..|.| ...|..|....:...|..|       ..|....:...||.| :.:
Mosquito   186 D-------RYGSQLIVRRKLVDRRRNLQGFAMPCGTATT-------SPEYFTGMDDRNDVHDLFT 236

  Fly   239 LARFGFHLTLILRDLLHCKMKFIFSDSWSKSDVVG--------GSVGAVVDQTADLTATPSLATE 295
            .|.|.|     :|:|::   ...|:.:..:.|.||        |.:|...:::.:|....:|...
Mosquito   237 KANFPF-----IRELMY---DLNFTLNMVQLDKVGYKQNGTFSGVMGKFQNRSIELGCLGTLMRT 293

  Fly   296 GRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFGGVLSLIGVLLWITFYMEC 360
            .||:....:|.|...:|..|||.| ...:..::|..|||..||.....:::    :.|:|. :..
Mosquito   294 ERLEVADFMIVTLIIKSSIIFRQP-PLSIVANIFELPFSVGVWACCFALMA----IYWMTM-IAI 352

  Fly   361 KRMQKRWRLDYLPSLLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYTSVVVSS 425
            :::....|...:.||:  ::|  |..|.:...::|:..|.||:.|:|.|.||.:...|::.:| :
Mosquito   353 RQLTSGERFGAIESLV--YII--GTMCQRGCDIVPQFNGTRLLMFSLQLTSFFILTSYSASIV-A 412

  Fly   426 LLSSPVKSKIKTMRQLAESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIESQTQNPELWLPAE 490
            ||.||.:: |.::..|..|.|..|:....:.:.|...::.|::....::||:...:  :.:|...
Mosquito   413 LLQSPSRA-IASVGDLVRSPLKAGVMDTSYGRVYYQETQDPDVQELYRKKIKPHGE--KAFLEPN 474

  Fly   491 QGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFYTHLHRNSTYKELFRLR 555
            :|:.||:... |.|..|.::.|..::..|..:|:|.|.|:.......|...:.:.|.|:||.|.|
Mosquito   475 EGIGRVKQEM-YAYEGELNAAYKVIKETFAPEEVCKLQELEAIKLPPFGIPIVKGSKYRELIRQR 538

  Fly   556 FLRILETGVYRKQRSYWVHMKLHCVAQNF-VITVGMEYVAPLLLMLICADILVVVILLVELAW 617
            .:...|.|:.::....|:|.|..|...|. ..:||:..:..|.|.|....:..:..||.|.:|
Mosquito   539 LMWQREVGIIKRFNLIWIHQKPQCENLNAGFSSVGVVEMRYLYLFLAVGFLAALATLLAERSW 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Periplasmic_Binding_Protein_Type_2	455..572	CDD:473866	26/116 (22%)
LOC1275780	XP_315067.5	None