Protein Alignment Ir75a and GRIN3B

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_619635.1
• Gene: GRIN3B / 116444
• HGNCID: 16768
• Length: 1043
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 88/463 - (19%)
• Similarity: 148/463 - (31%)
• Gaps: 183/463 - (39%)

  Fly   236 IDSLAR------FGFHLTLI-------LRDLLHCKMKFIFSDSWSKSDVVGGSVGAVVDQTADLT 287
            ||.|.|      |.|.|.|:       |||           ..|:      |.||.::...|.:.
Human   481 IDLLERLAEDTPFDFELYLVGDGKYGALRD-----------GRWT------GLVGDLLAGRAHMA 528

  Fly   288 ATPSLATEGRLKYLSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFS----PLVWYLFGGVLSLI 348
            .|.......|    |.:::   |.|. .|.|.....:|......|..    ||.|..:.||.:.:
Human   529 VTSFSINSAR----SQVVD---FTSP-FFSTSLGIMVRARDTASPIGAFMWPLHWSTWLGVFAAL 585

  Fly   349 GV-LLWITFYMECKRMQKRWR---------------LDYLPSLLSTFLISFGAACIQSSSLIPRS 397
            .: .|::|.|        .||               ..|..:|...:.|.|....   ||..|:.
Human   586 HLTALFLTVY--------EWRSPYGLTPRGRNRSTVFSYSSALNLCYAILFRRTV---SSKTPKC 639

  Fly   398 AGGRLIYFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLA-------------------- 442
            ..|||:.....:...::.:.||:.:.:.::..      ||..:|:
Human   640 PTGRLLMNLWAIFCLLVLSSYTANLAAVMVGD------KTFEELSGIHDPKLHHPAQGFRFGTVW 698

  Fly   443 ESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRK--------IESQTQNP---------------E 484
            |||          .::|:..| .|::|..::|.        :...|.:|               |
Human   699 ESS----------AEAYIKKS-FPDMHAHMRRHSAPTTPRGVAMLTSDPPKLNAFIMDKSLLDYE 752

  Fly   485 LWLPAEQGVLRVRDNPGYVYVFE------------TSSGYAYVERYFTAQEICDLNEVLFR---- 533
            :.:.|:..:|.|    |..:..|            ||:...::.||.::..|..|::..::
Human   753 VSIDADCKLLTV----GKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKMVPC 813

  Fly   534 PEQLF-YTHLHRNSTY-----------------------KELFRLRFLRILETGVYRK--QRSYW 572
            .:::| .|...:.|.|                       ...|||...||      ||  :..||
Human   814 GKRVFAVTETLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAFFRLALPRI------RKGSRLQYW 872

  Fly   573 VH--MKLH 578
            :|  .|:|
Human   873 LHTSQKIH 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	61/345 (18%)
GRIN3B	NP_619635.1	PBP1_iGluR_NMDA_NR3	19..405	CDD:107372
		PBP2_iGluR_NMDA_Nr3	415..808	CDD:270438	72/383 (19%)
		Lig_chan	576..842	CDD:278489	48/297 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155920
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740