Protein Alignment Ir75a and grid2

DIOPT Version :10

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_031759030.1
• Gene: grid2 / 100487676
• XenbaseID: XB-GENE-955038
• Length: 1007
• Species: Xenopus tropicalis
• Alignment Length: 615
• Identity: 116/615 - (18%)
• Similarity: 226/615 - (36%)
• Gaps: 176/615 - (28%)

  Fly    91 LLEEASREQIYNQHYH--------------WLLVGNQSKLEFYDLFGLFNISIDADVSYVKEQIQ 141
            ||..|..:::.::.:|              |  .|.:|.||.....|:..::...|.|      :
 Frog   333 LLANAFHKKLEDRKWHSMASLTCIRKNSKPW--QGGRSMLETVKKGGVSGLTGALDFS------E 389

  Fly   142 D-NNDSVAYAVHDVYNNGKIIGGQLN-------VTGSHEMSCDPFVCRRTRHLSSLQKRSKYGNR 198
            | .|.::.:.:... |.|:.:|..:.       |||.:               .||..|....|
 Frog   390 DGGNPNIYFEILGT-NYGEELGRGIRKLGFWNPVTGLN---------------GSLTDRKLENN- 437

  Fly   199 EQLTDVVLRVATVVTQRPLTLSDDELI----RFLSQENDTHIDSLARF-GFHLTLILRDLLHCKM 258
              :..||||||||: :.|..:..:.::    ::.....|. :|:|:.: ||...:
 Frog   438 --MRGVVLRVATVL-EEPFVMVSENVLGKPKKYQGFSIDV-LDALSSYLGFKYEI---------- 488

  Fly   259 KFIFSD----------SWSKSDVVGGSVGAVVDQTAD-----LTATPSLA-----TEGRLKYLSA 303
             ::.||          ||:      |.:|.::.:.||     ||.||...     |...:.|...
 Frog   489 -YVASDHKYGSPQADGSWN------GLIGELLLKRADMGISALTITPDRENVVDFTTRYMDYSVG 546

  Fly   304 IIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFGGVLSLIGVLLWITFYMECKRMQKRWR 368
            ::.....::|.:|           ..|.||...:|....|.:.|:|:|:::..::...|:|
 Frog   547 VLLRKAEKTVDMF-----------ACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQ---- 596

  Fly   369 LDYLPSLLSTFLIS-----FGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYTSVVVSSLLS 428
               :.|:.||.|.:     :|:...|...:...:...|::..|.:|.:.|:.:.||:.:.:.|..
 Frog   597 ---MGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTI 658

  Fly   429 SPVKSKIKTMRQLA----------------ESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIE 477
            |.::|.|::::.|:                |.....|:.|......|....|:      |.|...
 Frog   659 SRIESSIQSLQDLSRQTDIPYGTVFDSAVYEHVRVKGMNPFERDSMYSQMWRM------INRSNG 717

  Fly   478 SQTQNPELWLPAEQGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEVLFRPEQLFYT-- 540
            |:....|    :.:|:.:|: :..|.:|::.    |.:|......:.|.           |||
 Frog   718 SENNVQE----SLEGIQKVK-HGNYAFVWDA----AVLEYIAINDQDCS-----------FYTVG 762

  Fly   541 ----------HLHRNSTYKELFRLRFLRILETGVYRKQRSYWVHMKLHCVAQNFVIT------VG 589
                      .|...|.|:::|..|.|.:.:.|.....:..|......|...:.:.|      :.
 Frog   763 NTIADRGYGIALQHGSPYRDIFSQRILELQQNGDMDILKHKWWPRNGQCELHSSMDTKQKGSSLD 827

  Fly   590 MEYVAPLLLMLICADILVVVILLVELAWKR 619
            ::..:.:..:|....:|...|.:||..|.:
 Frog   828 IKSFSGVFCILAAGIVLSCFIAMVETWWNK 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Periplasmic_Binding_Protein_Type_2	455..572	CDD:473866	23/128 (18%)
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:471960	20/119 (17%)
		PBP2_iGluR_delta_2	440..806	CDD:270449	84/428 (20%)