Protein Alignment Ir75a and grik3

DIOPT Version :10

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_017206939.1
• Gene: grik3 / 100334689
• ZFINID: ZDB-GENE-211021-1
• Length: 991
• Species: Danio rerio
• Alignment Length: 676
• Identity: 136/676 - (20%)
• Similarity: 242/676 - (35%)
• Gaps: 204/676 - (30%)

  Fly    85 CDQTQ--DLLEEASREQIYNQHYHW------LLVGNQSKLEFYDL----FGLFNI---------- 127
            |..|.  .:|::|....:..::||:      |:..|.....|..:    |.:.|:
Zfish   227 CSHTMAAQILKQAQMMGMMTEYYHYIFTTLDLMAINLEPYRFCGVNMTGFRILNVDNPQVASIVE 291

  Fly   128 --SIDADV-----SYVKEQIQDNNDSVAY-AVHDVYNNGKIIGGQLNVTGSH--EMSCDPFVCRR 182
              |::..:     |.:.|.|...:.::.| |||.|           :|:..|  :|:.:...|.|
Zfish   292 KWSLERQIPPKPDSGLLEGIMTTDAALTYDAVHIV-----------SVSYQHAPQMTVNSLQCHR 345

  Fly   183 -------TRHLS------------------------------------SLQKRSKYG-------- 196
                   .|.:|                                    .|||..|:.
Zfish   346 HKPWRFGGRFMSFIKESHWDGLTGRLCFNRTTGLRTDFDLDIVSLKEDGLQKVGKWSASGGLNIT 410

  Fly   197 -----NREQLTDVVLR---VATVVTQRP---LTLSDDELI---RF------LSQENDTHIDSLAR 241
                 |...:||.:..   |.|.:.:.|   |..||..|:   ||      |.:|    :.|:..
Zfish   411 EVPRQNGMNITDSLSNRSLVITTILEEPYVMLKKSDKALVGNDRFEGFCIDLLKE----LASILG 471

  Fly   242 FGFHLTLILRDLLHCKMKFIFSD---SWSKSDVVGGSVGAVVDQTADLTATPSLAT---EGRLKY 300
            |.:.:.|:...      |:.|.|   .|:      |.:..:::..|||...|...|   |..:.:
Zfish   472 FSYEIHLVPDG------KYGFQDDKGQWN------GMIRELMEHRADLAVAPLTITFMREKAIDF 524

  Fly   301 LSAIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVW-YLFGGVLSLIGVLLWITFYMECKRMQ 364
            ....:.||.  |: ::|.|::.......||.|.:|.:| |:....|.:..||..|..:...:
Zfish   525 SKPFLNTGI--SI-LYRKPNSTNSGFFSFLNPMTPDIWVYILLAYLGVSCVLFVIARFSPYE--- 583

  Fly   365 KRWRLDYLP------------SLLSTFLISFGAACIQSSSLIPRSAGGRLI-----YFALFLISF 412
              | .|..|            :||::|....|:...|.|.|:|::...|:|     :|.|.:||
Zfish   584 --W-YDAHPCNPGSDVVENNFTLLNSFWFGVGSLMQQGSELMPKALSTRIIGGIWWFFTLIIIS- 644

  Fly   413 IMYNYYTSVVVSSLLSSPVKSKIKTMRQLA-ESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKR-K 475
                .||:.:.:.|....:.|.:.:...|| ::.:..|:.....|.|:...||   :..|.|. .
Zfish   645 ----SYTANLAAFLTVERMDSPVDSADDLAKQTKIEYGVVKDGATMSFFKKSR---VSTFEKMWA 702

  Fly   476 IESQTQNPELWLPAEQGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDLNEV---------- 530
            ..|..|:.......|.|:.||..: .|..:.| |:...||.|     ..|:|.:|
Zfish   703 FMSSRQSTSFVKSIEDGIQRVLKS-DYALLME-STTIEYVTR-----RNCNLTQVGGIIDSKGYG 760

  Fly   531 LFRPEQLFYTHLHRNSTYKELFRLRFLRILETG-VYRKQRSYWVHMKLHCVAQNFVIT--VGMEY 592
            :..|         :.|.|::...:..|.|||.| ::..:..:|....  |:......|  :|::.
Zfish   761 IGTP---------KGSPYRDKITIAILGILEDGRLHMLKEKWWSGSS--CLEDERYETGPMGIQN 814

  Fly   593 VAPLLLMLICADILVVVILLVELAWK 618
            :..:.::|....:|.|.:.:.|..:|
Zfish   815 LGGIFIVLASGLVLSVFVAIGEFIYK 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Periplasmic_Binding_Protein_Type_2	455..572	CDD:473866	29/128 (23%)
grik3	XP_017206939.1	PBP1_iGluR_Kainate	32..410	CDD:380605	31/193 (16%)
		Periplasmic_Binding_Protein_Type_2	426..794	CDD:473866	93/416 (22%)