Protein Alignment Ir75a and grin3bb

DIOPT Version :9

• Sequence 1: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_017213803.2
• Gene: grin3bb / 100333101
• ZFINID: ZDB-GENE-131122-77
• Length: 1114
• Species: Danio rerio
• Alignment Length: 827
• Identity: 149/827 - (18%)
• Similarity: 260/827 - (31%)
• Gaps: 323/827 - (39%)

  Fly     3 LVQLANFVLDNLVQSRIGF----IVLFHCWQSD---ESLKFAQQF-MKPIHPILVYHQFVQMRGV 59
            ||:|...||     .|.|:    .||.|.|:..   :.||...:| ..|..    :|    :|..
Zfish   170 LVELLLAVL-----QRSGWEESMAVLCHGWEDAGLLDLLKLQGRFGWGPSQ----WH----LRAA 221

  Fly    60 LNWSH------------LELSYMGHTQP--TLAIYVDIKCDQTQDLLEEASREQIYNQHYHWLL- 109
            ||.||            .|...:.|:.|  .|....|.:|  ...:|..|....:.....||::
Zfish   222 LNLSHSTARMANISDFLSEHFNLDHSPPASVLLFGADPEC--ASSVLRSAHDLGLTLPTVHWIMG 284

  Fly   110 ----------VG-----------NQSKLEFY--DLFGLFNISIDA------DVSYVKEQIQ--DN 143
                      :|           :...|:||  |...|.|.::.|      |::.::..:.  |.
Zfish   285 HPLSPDALHSIGLPLGLLAYGEVDHKPLDFYISDALQLINRAVTAATVVRPDLALIQNMVNCFDK 349

  Fly   144 NDSVAYAVHDVYNNGKIIGGQLNVTGSHEMSCDPFVCRRTR---------HLSSLQK-------- 191
            .:.     |::.::|:.|...|:.|....:: .|.:.:|..         |:.||::
Zfish   350 PNK-----HELPSSGQYIARFLSNTSFVGLT-GPVIVQRNLSRVHTSHKVHIWSLRRDAVGQPTW 408

  Fly   192 ---RSKYGNR----EQ----------------------------LTDVVLRVATVVTQRPLTLSD 221
               .|..|.|    ||                            ::...|||.|:| :.|...:.
Zfish   409 VTVGSWEGGRLNVEEQGLWQGSSPRQRTEGQMGREGRRWRAGFPVSGSRLRVVTLV-EHPFVFTR 472

  Fly   222 -------------------------DELIRFLSQENDTHID---SLARFGFHLTLILRDLLHCKM 258
                                     |.|....:|.|.:.:.   |...:|:.:.|:  :.|...|
Zfish   473 EVDEDGNCPAGQYCLDAGTNSSETLDHLYAERAQGNKSFLPPDYSKCCYGYCIDLL--EKLSEDM 535

  Fly   259 KFIFSDSWSKSD-----VVGGS----VGAVVDQTADLTATPSLATEGRLKYLSAIIETGFFRSV- 313
            .|.| |.:...|     |.||.    ||.::...||:..|.......|.|.:.  ..:.||.:.
Zfish   536 NFEF-DLYIVGDGKYGAVKGGQWTGLVGDLLSGVADMAVTSFSINSARSKVID--FTSPFFSTSL 597

  Fly   314 -CIFRTPHNAGLRGDVFLQPFSPLVWYLFGGVLSLIGV-LLWITFYMECKRMQKRWR-------- 368
             .:.|:...|...| .|:.   ||.|.::.|:...:.: .|::|.|        .|:
Zfish   598 GILVRSKDTAAPIG-AFMW---PLHWSMWMGIFVALHITALFLTLY--------EWKSPFGMTPH 650

  Fly   369 -------LDYLPSLLSTFLISFGAACIQSSSLIPRSAGGRLIYFALFLISFIMYNYYTSVVVSSL 426
                   ..|..:|...:.|.||...   ||..|:...||.:.....:...::.:.||:.:.:.:
Zfish   651 GRNRVKVFSYSSALNLCYAILFGRTV---SSKTPKCWTGRFLMNLWAIFCLLVLSSYTANLAAVM 712

  Fly   427 LSSPVKSKIKTMRQ--------------LAESSLTVGLEPLPFTKSYLNYSRLPEIHLFIKRKIE 477
            :......::..:..              :.|||          .:.|:..| .||:|.::::..|
Zfish   713 VGEKTFEEVSGIHDAKLHHPSQGFRFGTVRESS----------AEDYMKKS-FPEMHEYMRKFNE 766

  Fly   478 SQTQNPELWLPAEQGVLRVRDNPGYVYVF---------ETS----------------SGYA---- 513
            ..|.:         ||..::.:|..:..|         |.|                .||.
Zfish   767 PTTPD---------GVATLKTDPPQLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLP 822

  Fly   514 -----------YVERYFT-----------------AQEICDLNEVLFRPEQLFYTHLHRNSTYKE 550
                       :|.||.:                 .:.:..:.|.|    |:...|      :..
Zfish   823 QNSPLTSNISEFVSRYKSDGYMDMLHDKWYKVVPCGKRVFAVTETL----QMGIRH------FSG 877

  Fly   551 LFRL----------------RFLRILETGVYRKQR-SYWVH--MKLH 578
            ||.|                .|.|::...:.|||: .||:|  .|:|
Zfish   878 LFVLLCVGVTGALLTLAGEHAFYRLVLPHIRRKQKFKYWLHTSQKIH 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	56/348 (16%)
grin3bb	XP_017213803.2	PBP1_iGluR_NMDA_NR3	29..428	CDD:107372	56/278 (20%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	76/435 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591229
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840