Protein Alignment Cln3 and cln-3.2

DIOPT Version :9

• Sequence 1: NP_001261999.1
• Gene: Cln3 / 39981
• FlyBaseID: FBgn0036756
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_491556.1
• Gene: cln-3.2 / 172171
• WormBaseID: WBGene00000540
• Length: 435
• Species: Caenorhabditis elegans
• Alignment Length: 426
• Identity: 172/426 - (40%)
• Similarity: 254/426 - (59%)
• Gaps: 51/426 - (11%)

  Fly    36 RDLTSYWILGLCNNYGYVVMLSAAHDIIKQFNPNDES--EESSSGRNCHLVSTGAILLADVLPSL 98
            |:..::|:||||||:.||||||||.||:::...:.|.  .|..:.|.|.::|||::||||::|:|
 Worm    13 RNSVAFWLLGLCNNFAYVVMLSAAKDILEKDAKHIEKPCREHVTTRECQMMSTGSVLLADIIPAL 77

  Fly    99 FVKILMPFF----PFWVNFRIALAVAFSAAGFLLVGFANAEWMALLGVIITSASSGIGETTFLAY 159
            .:||..|.|    ||.:  |.::.|...|:.||:||.:::..:||.||::.|..||:||.::||.
 Worm    78 LIKITAPMFIHRVPFGI--RHSIVVLLQASSFLIVGISDSTALALFGVVLASFGSGLGEISYLAL 140

  Fly   160 SSRYNKNVISTWSSGTGGAGVIGSLSYASL---RSLDFSPRDTMLIMLIFPAIEAFAFWLLLRRP 221
            ||.|...|:::|||||||||:||:.:||.|   :.|..||:.||.|||..||:.:.::|.:|:.|
 Worm   141 SSNYPSTVVASWSSGTGGAGLIGASAYALLTDSKLLAISPKHTMFIMLTLPALFSVSYWSILKIP 205

  Fly   222 QV----------------DILPVTTVESTEVLISDEKPLVGFKE-----------------KLFY 253
            ..                |.:|...:...||  .:|:.|:|.:|                 .|..
 Worm   206 HSVQRAHFLQPSTWLVTGDFIPADDMRREEV--EEEEGLLGIREDRENSVDVTSRRRQTSTTLER 268

  Fly   254 IKHLFKYMLPLCLVYFFEYFINQGLFELVYFE---DIFLDKDSQYRWLNVDYQIGVFISRSSVNL 315
            :..|.|:|:||..||..||:|||||.||:.|:   ...:..:|||||..|.||:||||||||.|.
 Worm   269 VLPLLKFMIPLISVYLAEYYINQGLLELLEFDCSHGFSMSSESQYRWFQVTYQLGVFISRSSSNY 333

  Fly   316 FQLDKIWL--MSIFQFVNVVYFLTEVIWWYTPSIWIVFAIVLWEGLLGGGAYVNTFYRMSKEISP 378
            ..:...:|  :::.|..|..:|....|:.:.|.|.|.|.::|:||||||.:|||||..:.|||..
 Worm   334 VTIPTQYLKSLAVLQIFNAGFFTITAIYSFLPHILIAFLVILFEGLLGGASYVNTFRAVHKEIPA 398

  Fly   379 ERQQFAMAMVVQSDSYGIALAGFLAIPVHNAICGLP 414
            :.::|:|.:|..||:.||..|||||:||||.||.:|
 Worm   399 DSREFSMGVVSISDTIGIVFAGFLAMPVHNRICSMP 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cln3	NP_001261999.1	CLN3	40..413	CDD:280623	170/419 (41%)
cln-3.2	NP_491556.1	CLN3	17..433	CDD:280623	170/419 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164184
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3880
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37259
Inparanoid	1	1.050	305	1.000	Inparanoid score	I1589
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54383
OrthoDB	1	1.010	-	-		D1037817at2759
OrthoFinder	1	1.000	-	-		FOG0004157
OrthoInspector	1	1.000	-	-		otm14074
orthoMCL	1	0.900	-	-		OOG6_102552
Panther	1	1.100	-	-	O	PTHR10981
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R153
SonicParanoid	1	1.000	-	-		X2906
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800