back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cln3 and Cln3

DIOPT Version :9

Sequence 1:	NP_001261999.1	Gene:	Cln3 / 39981	FlyBaseID:	FBgn0036756	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001139783.1	Gene:	Cln3 / 12752	MGIID:	107537	Length:	438	Species:	Mus musculus

Alignment Length:	441	Identity:	180/441 - (40%)
Similarity:	262/441 - (59%)	Gaps:	50/441 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QEAEAEHDPQVVVTPGDASRSSRQDRGLWRDLTSYWILGLCNNYGYVVMLSAAHDIIKQF----- 66
            :..|.:.:||   .|...|||.     ||::...:||||||||:.|||||||||||:||.
Mouse    15 EREETDSEPQ---APRLDSRSV-----LWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASGN 71

  Fly    67 ------NPNDESEESSSGRNCHLVSTGAILLADVLPSLFVKI-------LMPFFPFWVNFRIALA 118
                  .|......|||..:|:.:||.|:||||:||:|.:|:       |:|:.|     |:.::
Mouse    72 QSHVEPGPTPTPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSP-----RVLVS 131

  Fly   119 VAFSAAGFLLVGFANAEWMALLGVIITSASSGIGETTFLAYSSRYNKNVISTWSSGTGGAGVIGS 183
            ...||..|:||.|:.:..::|.||::.|.|||:||.|||:.::.|...|||.|||||||||::||
Mouse   132 GVCSAGSFVLVAFSQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGS 196

  Fly   184 LSYASLRSLDFSPRDTMLIMLIFPAIEAFAFWLLLRRPQVDILPVTTVESTEVLISDEKPLVG-- 246
            |||..|.....||:.|:|.||..|.:...:::|||..|:    |:......|...:..:||:|
Mouse   197 LSYLGLTQAGLSPQHTLLSMLGIPVLLLASYFLLLTSPE----PLDPGGENEAETAARQPLIGTE 257

  Fly   247 -------------FKEKLFYIKHLFKYMLPLCLVYFFEYFINQGLFELVYFEDIFLDKDSQYRWL 298
                         .:|:....|.|..|::||.||||.|||||||||||::|.:..|....||||.
Mouse   258 TPESKPGASWDLSLQERWTVFKGLLWYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWY 322

  Fly   299 NVDYQIGVFISRSSVNLFQLDKIWLMSIFQFVNVVYFLTEVIWWYTPSIWIVFAIVLWEGLLGGG 363
            .:.||.|||.||||:...::...|::::.|.:|:...|.:|...:.|||:::|.|:|:||||||.
Mouse   323 QMLYQAGVFASRSSLQCCRIRFTWVLALLQCLNLALLLADVCLNFLPSIYLIFIIILYEGLLGGA 387

  Fly   364 AYVNTFYRMSKEISPERQQFAMAMVVQSDSYGIALAGFLAIPVHNAICGLP 414
            ||||||:.::.|.|.:.::|||.....||:.||:|:|.||:|:|:.:|.||
Mouse   388 AYVNTFHNIALETSDKHREFAMEAACISDTLGISLSGVLALPLHDFLCHLP 438

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.