Protein Alignment CG5589 and DDX59

DIOPT Version :9

• Sequence 1: NP_649009.1
• Gene: CG5589 / 39979
• FlyBaseID: FBgn0036754
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001026895.2
• Gene: DDX59 / 83479
• HGNCID: 25360
• Length: 619
• Species: Homo sapiens
• Alignment Length: 567
• Identity: 178/567 - (31%)
• Similarity: 262/567 - (46%)
• Gaps: 78/567 - (13%)

  Fly    15 RFTKKSKKEPSSKQQLQPLPEVSKH---------EEPVKSEES---------------------- 48
            |...:|...||...||..:..||..         ||||||...
Human    54 RHISESCPFPSPGGQLAEVHSVSPEQGAKDSHPSEEPVKSFSKTQRWAEPGEPICVVCGRYGEYI 118

  Fly    49 -DKDDEDITEFR------LLDGDSSNQPKRKKPKK-----EKTLS--------PKELEIQKAAEE 93
             ||.|||:....      |...:...:.|...|:|     |..|:        |..|.:|:  ::
Human   119 CDKTDEDVCSLECKAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQE--DQ 181

  Fly    94 ANETRKQYGIRVLGKNVPPPVDSFGTLTRDFKMLPR-LQQNLLSRNFDHPTPIQMQALPVLLQRR 157
            ....::|.||.|.|:.|..|:..|     :...||. |..||....::.|||||||.:||.|..|
Human   182 IENLKQQLGILVQGQEVTRPIIDF-----EHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGR 241

  Fly   158 ALMACAPTGSGKTLAFLTPII-NGLRAHKTTGLRALVLAPTRELAQQIYRECAELTRETGL---- 217
            .::|.|.||||||.|||.|:| ..|...||..  ||:|.||||||.||.|:..||.  :||
Human   242 DILASADTGSGKTAAFLLPVIMRALFESKTPS--ALILTPTRELAIQIERQAKELM--SGLPRMK 302

  Fly   218 RTHFISKVSEAKQKHGAECKQRYDILVSTPNRVRFLLQQEPPLLDLSHVEWFVLDEADRLMEEGQ 282
            ....:..:....|.:  ..:|...::::||.|:..:::|..  ::|..|:..|:||||.:::.|
Human   303 TVLLVGGLPLPPQLY--RLQQHVKVIIATPGRLLDIIKQSS--VELCGVKIVVVDEADTMLKMG- 362

  Fly   283 NNFKEQLDDIYAACSNPTKCVAFFSATYTVPVAKWALRHLKNLVRITIGVQNSATETVQQELLFV 347
              |::|:.||.....|..:.: ..|||....:.:.|.:.|.|.|||..|.:|.....|:|.:|:|
Human   363 --FQQQVLDILENIPNDCQTI-LVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWV 424

  Fly   348 GSEGGKLVAIRDLVRQGL-QPPVLVFVQSKERAKQLFEEL-LYDGINVDVIHAERSQHQRDNCVK 410
            .....|......|..:.| :|||||||..|..|..|.|.: ...|:....||:|:||.:|.|.:|
Human   425 EDPAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILK 489

  Fly   411 AFREGSIWVLICTELMGRGIDFKGVNLVINYDFPPTTISYIHRIGRTGRAGRPGRAITFFTQEDT 475
            ...||...|::.|.::|||:|...|.||:|:|.|.:...|:|:|||.||.|:.|.||||......
Human   490 GLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSK 554

  Fly   476 SNLRGIALIIKNSGGTVPEYMLQMKKVRKSEAKMRAKKPLDREDIST 522
            .....||..:|.:|..:|..:|....:...:.|.:.|....:.|:.|
Human   555 RLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQNDLVT 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5589	NP_649009.1	SrmB	87..594	CDD:223587	151/444 (34%)
		P-loop_NTPase	123..329	CDD:304359	75/211 (36%)
		HELICc	349..469	CDD:238034	48/121 (40%)
DDX59	NP_001026895.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	57..98		13/40 (33%)
		DEXDc	89..592	CDD:331760	166/521 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..161		4/18 (22%)
		Q motif	203..231		10/32 (31%)
		DEAD box	353..356		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D400908at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920