Protein Alignment CG5589 and ddx52

DIOPT Version :9

• Sequence 1: NP_649009.1
• Gene: CG5589 / 39979
• FlyBaseID: FBgn0036754
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: XP_012816864.1
• Gene: ddx52 / 496953
• XenbaseID: XB-GENE-993518
• Length: 614
• Species: Xenopus tropicalis
• Alignment Length: 621
• Identity: 259/621 - (41%)
• Similarity: 376/621 - (60%)
• Gaps: 79/621 - (12%)

  Fly     1 MDEHDIFKLITAGVRF--------TKKSKKEPSSKQQLQPLPEVSK-----HEEPVKSEESDKDD 52
            ||..|:|:.:.:|.:|        .:|.|.:..::..|.....:..     :||.:.|:..|. .
 Frog     1 MDAFDLFRKLGSGAKFDLKRFSGDAEKFKVKKGNESILNSSTALKSLDFFGNEEKILSKTIDL-S 64

  Fly    53 EDITEFRLLDGDSSNQPKRKKPKKE--------------------------------------KT 79
            :|:.:..  :|||....|..|.||:                                      |.
 Frog    65 KDLNKSE--NGDSGVTNKASKRKKDLKKGGKKCKIQEQDAGGCSAADDSIHWMSSLEAKLKDGKE 127

  Fly    80 LSPKELEIQK----AAEEANETRKQYGIRVLGKNVPPPVDSFGTLTRDFKMLPRLQQNLLSRNFD 140
            .|.::|.:.|    ..|:.|..|.::.|.|.|.::|.||.:|..|.:::|...::.||:....|.
 Frog   128 KSKRKLTVDKMKQLRLEKINHFRNEHKIYVQGTDIPEPVATFQQLEQEYKTHSKIIQNVKDFGFH 192

  Fly   141 HPTPIQMQALPVLLQRRALMACAPTGSGKTLAFLTPIINGLRAHKTTGLRALVLAPTRELAQQIY 205
            .||||||||:|::|..|.::|.||||||||:||..||:..|:..|..|.|||:::||||||.|.:
 Frog   193 TPTPIQMQAIPIMLHGREILASAPTGSGKTMAFSIPILAHLQCPKNKGCRALIISPTRELANQTH 257

  Fly   206 RECAELTRETGLRTHFISKVSEAKQKHGAECKQRYDILVSTPNRVRFLLQQEPPLLDLSHVEWFV 270
            ||..:|:...|.|.|.|:|.:.|.:|.|.:..::.||||:||||:.:||:|:||.:|||.|||.:
 Frog   258 RELVKLSDGIGFRIHVINKAAVAAKKFGPKSSKKIDILVTTPNRLIYLLKQDPPGIDLSSVEWLI 322

  Fly   271 LDEADRLMEEGQNNFKEQLDDIYAACSNPTKCVAFFSATYTVPVAKWALRHLKNLVRITIGVQNS 335
            :||:|:|.|:|:..|::||..|:.||::.....|.||||:...|.:|...||.|:|.::||.:||
 Frog   323 VDESDKLFEDGKTGFRDQLASIFVACTSHLLKRAMFSATFAFDVEQWCKLHLDNVVSVSIGARNS 387

  Fly   336 ATETVQQELLFVGSEGGKLVAIRDLVRQGLQPPVLVFVQSKERAKQLFEELLYDGINVDVIHAER 400
            |.|||:|.|||||||.|||:|:||||::|..|||||||||.||||:||.||:|:|||||||||||
 Frog   388 AVETVEQSLLFVGSETGKLLAMRDLVKKGFTPPVLVFVQSIERAKELFHELIYEGINVDVIHAER 452

  Fly   401 SQHQRDNCVKAFREGSIWVLICTELMGRGIDFKGVNLVINYDFPPTTISYIHRIGRTGRAGRPGR 465
            :|.||||.:::||||.|||||||.|:.|||||||||:|||||||.:.:.||||||||||||..|:
 Frog   453 TQQQRDNVIQSFREGKIWVLICTALLARGIDFKGVNMVINYDFPTSAVEYIHRIGRTGRAGHRGK 517

  Fly   466 AITFFTQEDTSNLRGIALIIKNSGGTVPEYMLQMKKVRKSEAKMRAKKPLDREDISTKIRPETKG 530
            |::|||::|...||.:|.:|:.:|..:|:|:...:|::..:.|...|:||.|:.|.|
 Frog   518 AVSFFTEDDKPMLRSVASVIQKAGCPIPDYIKSFRKLQSKQKKRMIKRPLKRDQIRT-------- 574

  Fly   531 DEKHKSTK--LKKVERTEKILKNRKGYEKDLNSKQK 564
                 :.|  |:|.:|...::|      |:|..|:|
 Frog   575 -----TPKYILEKAKRKRDVIK------KNLKKKEK 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5589	NP_649009.1	SrmB	87..594	CDD:223587	235/484 (49%)
		P-loop_NTPase	123..329	CDD:304359	94/205 (46%)
		HELICc	349..469	CDD:238034	87/119 (73%)
ddx52	XP_012816864.1	SrmB	135..587	CDD:223587	230/464 (50%)
		DEADc_DDX52	182..383	CDD:350715	93/200 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I3614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H5093
Inparanoid	1	1.050	475	1.000	Inparanoid score	I1448
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D323399at33208
OrthoFinder	1	1.000	-	-		FOG0003197
OrthoInspector	1	1.000	-	-		oto103445
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1170
SonicParanoid	1	1.000	-	-		X3665
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.090