Protein Alignment CG5589 and Hlc

DIOPT Version :9

• Sequence 1: NP_649009.1
• Gene: CG5589 / 39979
• FlyBaseID: FBgn0036754
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001285517.1
• Gene: Hlc / 33118
• FlyBaseID: FBgn0001565
• Length: 560
• Species: Drosophila melanogaster
• Alignment Length: 519
• Identity: 135/519 - (26%)
• Similarity: 221/519 - (42%)
• Gaps: 104/519 - (20%)

  Fly   117 FGTLTRDFKMLPRLQQNLLSRNFDHPTPIQMQALPVLLQRRALMACAPTGSGKTLAFLTPIINGL 181
            |..|..|.::|..:.|    ..:..||.||..|:|:||:.:.::..|.||||||..:..|:|..:
  Fly    11 FHELELDQRILKAVAQ----LGWQQPTLIQSTAIPLLLEGKDVVVRARTGSGKTATYALPLIQKI 71

  Fly   182 RAHKTTG----LRALVLAPTRELAQQIYRECAELTRETGLRTHFISKVSEAKQKHGAECKQRY-- 240
            ...|...    :.|:|||||:||.:|..:...:|....|.    :.:|::..........||:
  Fly    72 LNSKLNASEQYVSAVVLAPTKELCRQSRKVIEQLVESCGK----VVRVADIADSSNDTVTQRHAL 132

  Fly   241 ----DILVSTPNRVRFLLQQEPPLLDLSHVEWFVLDEADRLMEEG-QNNFK---EQLDDIYAACS 297
                ||:|:||..: ....:...::||.|||..|:||||.:...| :.:||   :.|..||.|
  Fly   133 SESPDIVVATPANL-LAYAEAGSVVDLKHVETLVVDEADLVFAYGYEKDFKRLIKHLPPIYQA-- 194

  Fly   298 NPTKCVAFFSATYTVPVAKWALRHLKNLVRITIGVQNSATETVQQELL----FVGSEGGKLVAIR 358
                  ...|||.|..|.:.....|.|.|.:.:    ...|.|.|:.|    .:..|..|...:.
  Fly   195 ------VLVSATLTDDVVRMKGLCLNNPVTLKL----EEPELVPQDQLSHQRILAEENDKPAILY 249

  Fly   359 DLVRQGL-QPPVLVFVQSKERAKQLFEELLYDGINVDVIHAERSQHQRDNCVKAFREGSIWVLIC 422
            .|::..| :...::||.|.:|..::...|...||...|:::|...:.|.:.:..|.:|:..::|.
  Fly   250 ALLKLRLIRGKSIIFVNSIDRCYKVRLFLEQFGIRACVLNSELPANIRIHTISQFNKGTYDIIIA 314

  Fly   423 TE-------------------------LMGRGIDFKGVNLVINYDFPPTTISYIHRIGRTGRAGR 462
            ::                         ...|||||:.||.|||:|||....|||||.|||.|...
  Fly   315 SDEHHMEKPGGKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNN 379

  Fly   463 PGRAITFFTQEDTSNLRGI-------------ALIIKNSGGTVPEYMLQMKKVR----KSEAKMR 510
            .|..::|.:.:::.....:             ..||||       |..:|::|.    :::...|
  Fly   380 KGSVLSFVSMKESKVNDSVEKKLCDSFAAQEGEQIIKN-------YQFKMEEVESFRYRAQDCWR 437

  Fly   511 AKKPLDREDISTKIRPETKGDEKHKSTKLKKVERTEKILKNRKGYEKDLNS--KQKKLGNIKTE 572
            |...:...|  |:|| |.|       .::...|:.:...:..|   :||.:  ..|.|..||.:
  Fly   438 AATRVAVHD--TRIR-EIK-------IEILNCEKLKAFFEENK---RDLQALRHDKPLRAIKVQ 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5589	NP_649009.1	SrmB	87..594	CDD:223587	135/519 (26%)
		P-loop_NTPase	123..329	CDD:304359	65/219 (30%)
		HELICc	349..469	CDD:238034	40/145 (28%)
Hlc	NP_001285517.1	P-loop_NTPase	11..220	CDD:304359	67/225 (30%)
		DEXDc	24..231	CDD:214692	66/227 (29%)
		HELICc	234..386	CDD:238034	40/151 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451742
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030