Protein Alignment CG5589 and CG6227

DIOPT Version :9

• Sequence 1: NP_649009.1
• Gene: CG5589 / 39979
• FlyBaseID: FBgn0036754
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_573020.2
• Gene: CG6227 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Alignment Length: 675
• Identity: 178/675 - (26%)
• Similarity: 294/675 - (43%)
• Gaps: 153/675 - (22%)

  Fly    10 ITAGVRFTKKSKKEPSSKQQLQP------LPEVSKHEEPVKSEESDKDDEDI------TEFRLLD 62
            :.||    :|:||||.     ||      .|||....:|....|.:.|..|.      .|.|.::
  Fly   336 VAAG----EKTKKEPE-----QPHVGAKSEPEVEDKPQPEAEPEDEIDPLDAYMQEVNNEMRRVN 391

  Fly    63 GDSSNQPKRKK-------PKKEKTLSPKELEI------------QKAAEEANET----------- 97
             :..|.|.:.:       ..|:||.:.|:.|:            :...|:..:|
  Fly   392 -NFVNPPAKSQGVVILTGVAKKKTTTLKKGEVIEQNMDSLEYSSEDELEDIRDTAVNLAMKHRKE 455

  Fly    98 --------------RKQY-----------------------GIRVLGKNVPPPVDSF---GTLTR 122
                          ||.:                       ||:|.||..|.|:.::   |...:
  Fly   456 LAKIDHSSVTYAPFRKNFYVEVPELTRMTAADVEKYRSDLEGIQVKGKGCPKPIKTWAQCGVSKK 520

  Fly   123 DFKMLPRLQQNLLSRNFDHPTPIQMQALPVLLQRRALMACAPTGSGKTLAFLTP----IINGLRA 183
            :.::|.||       .|:.|||||.||:|.::..|.|:..|.|||||||||:.|    |::....
  Fly   521 EMEVLRRL-------GFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILDQPSM 578

  Fly   184 HKTTGLRALVLAPTRELAQQIYRECAELTRETGLRTHFI---SKVSE--AKQKHGAECKQRYDIL 243
            ....|..|:::||||||..||.::..:.::..|||...:   :.:||  |:.|.|||      |:
  Fly   579 EDGDGAIAIIMAPTRELCMQIGKDIRKFSKSLGLRPVCVYGGTGISEQIAELKRGAE------II 637

  Fly   244 VSTPNR-VRFLLQQEPPLLDLSHVEWFVLDEADRLMEEGQNNFKEQ----LDDIYAACSNPTKCV 303
            |.||.| :..|......:.:|..|.:.|||||||:.:.|   |:.|    :|::     .|.:..
  Fly   638 VCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMG---FEPQVMRIIDNV-----RPDRQT 694

  Fly   304 AFFSATYTVPVAKWALRHLKNLVRITIGVQNSATETVQQELLFVGSEGG--KLVAIRDLVRQGLQ 366
            ..||||:...:...|.|.||..:.:.:|.::...:.|:|.::.:..:..  ||:.:..:.::.
  Fly   695 VMFSATFPRQMEALARRILKKPIEVIVGGRSVVCKEVEQHVVILNDDAKFFKLLELLGIYQEA-- 757

  Fly   367 PPVLVFVQSKERAKQLFEELLYDGINVDVIHAERSQHQRDNCVKAFREGSIWVLICTELMGRGID 431
            ..::|||..:|.|..|..:|:........:|....|..||:.:..|:.|.:.:||.|.:..||:|
  Fly   758 GSIIVFVDKQENADILLRDLMKASYPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLD 822

  Fly   432 FKGVNLVINYDFPPTTISYIHRIGRTGRAGRPGRAITFFTQEDTSNLRGIALIIKNSGGTVPEYM 496
            .|.:.||:|||.|.....|:||.|||||||:.|.|.||.|.|.:.....|...:..||..:|..:
  Fly   823 VKDLILVVNYDVPNHYEDYVHRCGRTGRAGKKGSAYTFITPEQSRYAGDIIRAMDLSGTLIPAEL 887

  Fly   497 ----LQMKKVRKSEAKMRAKKPLDREDISTKIRPETKG---DEKH-----KSTKLKKVERTEKIL 549
                .:.|.::::|.|          .:.|......||   ||:.     :|.||:|........
  Fly   888 QALWTEYKALQEAEGK----------TVHTGGGFSGKGFKFDEQEFNAAKESKKLQKAALGLADS 942

  Fly   550 KNRKGYEKDLNSKQKKLGNIKTELK 574
            .:.:..|:|::.:.:::...|..:|
  Fly   943 DDEEDIEQDIDQQIEQIFAAKRTVK 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5589	NP_649009.1	SrmB	87..594	CDD:223587	153/579 (26%)
		P-loop_NTPase	123..329	CDD:304359	74/219 (34%)
		HELICc	349..469	CDD:238034	40/121 (33%)
CG6227	NP_573020.2	SrmB	482..967	CDD:223587	148/517 (29%)
		DEADc	516..719	CDD:238167	75/223 (34%)
		HELICc	733..860	CDD:238034	41/128 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451467
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940