Protein Alignment CG5589 and ddx-52

DIOPT Version :9

• Sequence 1: NP_649009.1
• Gene: CG5589 / 39979
• FlyBaseID: FBgn0036754
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_492326.1
• Gene: ddx-52 / 172651
• WormBaseID: WBGene00011032
• Length: 581
• Species: Caenorhabditis elegans
• Alignment Length: 626
• Identity: 228/626 - (36%)
• Similarity: 340/626 - (54%)
• Gaps: 93/626 - (14%)

  Fly     7 FKLITAGVRFTKKSKKEP---SSKQQLQPLPE-----------------VSKHEEPVKSEESDKD 51
            |:.::.|::.::..||:.   :.|::|..:.|                 .||.|:.||..:....
 Worm     5 FRTLSFGIKRSQPKKKDADDLNKKKELSTITEESLRRYDELREKMIGKVESKIEKKVKKNKKKAS 69

  Fly    52 DEDITEFRLL---DGDSSNQPKRKKPKKEKTLSPKELEIQKAAEEANETRKQYGIRVLGKNVPPP 113
            .|.:...:.:   ||||.|:       .|:|:...|..:||..::...|.:   |...|.::|..
 Worm    70 IEILASRKRVHDSDGDSENE-------VEETVGDVEKRMQKLLDDIRRTNR---IFTWGDHLPNI 124

  Fly   114 VDSFGTLTRDFKMLPRLQQNLLSRNFDHPTPIQMQALPVLLQRRALMACAPTGSGKTLAFLTPII 178
            :..|.    |..|.|.|...|...:...|:|||||::|.:.:||.::|.|||||||||||..|:|
 Worm   125 ILRFS----DSSMSPSLLNRLSENSIRQPSPIQMQSIPFMTERRNVLASAPTGSGKTLAFALPVI 185

  Fly   179 NGL---------RAHKTTGLRALVLAPTRELAQQIYRECAELTRETGLRTHFISKVSEAKQKHGA 234
            :.:         .:..::.|.|:||.||||||.|.|.|..:....|.:         .|....|.
 Worm   186 DEILELKQRADYSSSNSSKLLAVVLEPTRELAAQTYTEFLKYCANTSI---------SAANFSGE 241

  Fly   235 ECK-QRYDILVSTPNRVRFLLQQEPPLLDLSHVEWFVLDEADRLME--EGQNN-FKEQLDDIYAA 295
            |.. |..|||||||||:.|.|.:    :|.|.:.|.|:||:|||.|  |||:. |:.||..||.|
 Worm   242 ETDIQHADILVSTPNRIVFHLDK----IDTSSLRWLVVDESDRLFEVVEGQDKCFRNQLAAIYKA 302

  Fly   296 CSNPTKC--VAFFSATYTVPVAKWALRHLKNLVRITIGVQNSATETVQQELLFVGSEGGKLVAIR 358
            |.  .||  |||||||::..|.||...::..:..:.:|.:||:..:|:|:|.:.|:|.||.:|||
 Worm   303 CD--AKCTRVAFFSATFSHEVEKWCKENIDEIGMVCVGERNSSNTSVKQKLTYCGTEDGKKIAIR 365

  Fly   359 DLVRQGLQPPVLVFVQSKERAKQLFEEL--LYDGINVDVIHAERSQHQRDNCVKAFREGSIWVLI 421
            :|:|...:||.|||||||:||.||.:.|  :...:.||.|::.:|..:||..::.||.|.||||:
 Worm   366 NLLRTSFKPPALVFVQSKDRAVQLVKLLSAIDSNLKVDSINSGKSDKERDETMERFRRGEIWVLV 430

  Fly   422 CTELMGRGIDFKGVNLVINYDFPPTTISYIHRIGRTGRAGRPGRAITFFTQEDTSNLRGIALIIK 486
            ||||:|||:|...|.||||||.|.:.:|||||:|||||||:.|.|:|:||..|...::.||.:|:
 Worm   431 CTELLGRGLDLSDVGLVINYDLPTSIVSYIHRVGRTGRAGKSGHAVTYFTDADMKYIKSIATVIR 495

  Fly   487 NSGGTVPEYMLQMKKVRKSEAKMRAKKPLDREDISTKIRPETKGDEKHKSTKLKKVERTEKILKN 551
            .||..||||:::||||.:           ||:....|..|     ::||...:|     |:::|.
 Worm   496 QSGFDVPEYLMEMKKVSR-----------DRKKDMLKHAP-----KRHKIAIVK-----EQVIKK 539

  Fly   552 RKGYEKDLNSKQKKLGNIKTELKPAGKRKGNVEKKTKNKNN 592
            :|...|  .:.::|..| |||.:.|.|.:..::||...|.|
 Worm   540 KKMLAK--AAAEEKAKN-KTETQTAEKPEKKIKKKKLIKKN 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5589	NP_649009.1	SrmB	87..594	CDD:223587	207/523 (40%)
		P-loop_NTPase	123..329	CDD:304359	89/220 (40%)
		HELICc	349..469	CDD:238034	65/121 (54%)
ddx-52	NP_492326.1	PTZ00424	124..505	CDD:185609	174/399 (44%)
		P-loop_NTPase	128..327	CDD:304359	90/217 (41%)
		HELICc	352..478	CDD:238034	66/125 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161240
Domainoid	1	1.000	123	1.000	Domainoid score	I3480
eggNOG	1	0.900	-	-		E1_KOG0344
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5093
Inparanoid	1	1.050	338	1.000	Inparanoid score	I1404
Isobase	1	0.950	-	0	Normalized mean entropy	S1012
OMA	1	1.010	-	-		QHG56500
OrthoDB	1	1.010	-	-		D323399at33208
OrthoFinder	1	1.000	-	-		FOG0003197
OrthoInspector	1	1.000	-	-		oto20031
orthoMCL	1	0.900	-	-		OOG6_102417
Panther	1	1.100	-	-	LDO	PTHR24031
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1170
SonicParanoid	1	1.000	-	-		X3665
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790