Protein Alignment CG42816 and ABCA4

DIOPT Version :10

• Sequence 1: NP_730301.3
• Gene: CG42816 / 39977
• FlyBaseID: FBgn0261998
• Length: 1459
• Species: Drosophila melanogaster
• Sequence 2: NP_001319703.1
• Gene: ABCA4 / 823929
• AraportID: AT3G47750
• Length: 937
• Species: Arabidopsis thaliana
• Alignment Length: 672
• Identity: 175/672 - (26%)
• Similarity: 306/672 - (45%)
• Gaps: 142/672 - (21%)

  Fly    43 FPPIKDLP-SPPIFKSDNSSTLQDVGIMIIVIIIFFVVVSLTKSIVEEKELQLKVTLNLMGVGSC 106
            |..:|::| ...:.:.|.:|.:..:.:..:::::|.|:::   |:|.||:..|::.:.:.|:|..
plant   323 FDFVKEMPKQESMLRVDIASVIGPIFLTWVIVLLFPVILN---SLVYEKQQHLRIIMKMHGLGDG 384

  Fly   107 LQWVAWY-----IQTFII---FLIGSSIITLFWKLVLPNSEISFMPFTHWSMALFVLLVLSHCTI 163
            ..|:..|     |.|..|   .:.||:|            .:.|..|..:|:......:..:..|
plant   385 PYWMITYAYFLAISTLYIICLMIFGSAI------------GLKFFRFNDYSIQFIFYFLCINLQI 437

  Fly   164 CFSFLMSSLISTTYRISLVTFLALIATYLPFLILHSKGCSEGLNVFLSLFLLSGLQV-------- 220
            ..:||:||..|.....|:..:|.:..:.|             |..||..|:|.||..
plant   438 SIAFLVSSAFSKVETASVAAYLYVFGSGL-------------LGGFLFQFMLEGLSFPRGWIFVM 489

  Fly   221 -------LVVGICMWEDY--------GEGLQWGNLFETSWPGGTLSVGYILLVMILASFLSLLLC 270
                   |..|:..:..|        .:|::| ..|..|      ::..:..::|:..||:|:..
plant   490 ELYPGFSLYRGLYEFSQYALKRQLNGSDGMKW-KYFSDS------AMDEVFYIIIIEWFLALIAA 547

  Fly   271 LYLEKIRPGPYGVPQPWHFPCTRCCSTESLLPYSRLFNRIFGIYSAAPDEERPDLQ------LIE 329
            .|::::                   |:.:..|:..|.|.|    ..:|..:|..||      .:|
plant   548 YYMDRV-------------------SSSAKDPFLFLKNLI----KKSPSPQRHSLQRLGSSVSVE 589

  Fly   330 PDPVD------KIAGVQIRG----------LSKTF-------GKMEVVKNVSFDMFEGQITVLMG 371
            .:.:|      |:..:.:..          |.|.:       .|| .|..:|..:..|:...::|
plant   590 MEKLDVVEERAKVEQLMLESSTSHAIVCDKLKKVYPGRDGNPPKM-AVGGLSIAVPPGECFGMLG 653

  Fly   372 HNGAGKTTLISMLAGFISPTSGTALINGFDIRQERRQAQRCIGLCPQQNVLFKHLSSVSHIQLFS 436
            .||||||:.|:|:.|.:.|||||||:...||.|:..:....:|:|||.::|::.|:...|:..:.
plant   654 PNGAGKTSFINMMTGLVKPTSGTALVESLDICQDMDKVYTSMGVCPQHDLLWETLTGREHLLFYG 718

  Fly   437 RLRGLRGAEVKSEVQNYLKKLNLQEKKRLA---ARNLSGGTQRRLSVACSLCGGVKVLICDEPST 498
            ||:.|:|:::...::..||.:|| .::.:|   |...|||.:||||||.||.|..||:..|||||
plant   719 RLKNLKGSDLNQAIEESLKSVNL-SREGVADKPAGKYSGGMKRRLSVAISLIGSPKVVYMDEPST 782

  Fly   499 GLDPSARRELWRLILEAKEGCTILLTTHQLDDGEVLGDRVVIISDGQLRCIGSLPFLKKQVDASC 563
            ||||::||.||..|..||:...|:||||.:::.|.|.||:.|..||:|:|:|:...||.:...|.
plant   783 GLDPASRRSLWTAIKGAKKHTAIILTTHSMEEAEFLCDRLGIFVDGRLQCVGNPKELKARYGGSY 847

  Fly   564 LI--TCEARKRCDLEKLTSLIS------RHVGTIQPFSIKGRDVCYKLPLSKSKYFSSLFRDLES 620
            ::  |..:....|:|.|...:|      .|:...|.|.|...:|          ..:.||:.:|.
plant   848 VLTMTTSSEHEKDVEMLIQDVSPNAKKIYHIAGTQKFEIPKDEV----------RIAELFQAVEK 902

  Fly   621 QMNILGVRGFSLSSVSLEEIFM 642
            ......|..:.|:..:||::|:
plant   903 AKGNFRVFAWGLADTTLEDVFI 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42816	NP_730301.3	rim_protein	<81..1451	CDD:130324	168/633 (27%)
ABCA4	NP_001319703.1	rim_protein	<346..>937	CDD:130324	170/649 (26%)
		ABC_subfamily_A	619..840	CDD:213230	89/222 (40%)