Protein Alignment CG42816 and abca7

DIOPT Version :9

• Sequence 1: NP_730301.3
• Gene: CG42816 / 39977
• FlyBaseID: FBgn0261998
• Length: 1459
• Species: Drosophila melanogaster
• Sequence 2: XP_009304071.2
• Gene: abca7 / 561460
• ZFINID: ZDB-GENE-050517-6
• Length: 2328
• Species: Danio rerio
• Alignment Length: 1709
• Identity: 442/1709 - (25%)
• Similarity: 741/1709 - (43%)
• Gaps: 424/1709 - (24%)

  Fly    46 IKDLPSPPIFKSDNSSTLQDVGIMII--------VIIIFFVVVSLTKSIVEEKELQLKVTLNLMG 102
            ::.:|.|        ..:.||.|.::        .:...:.|..:.|.:|.|||.:||.|:.:||
Zfish   627 VQQMPYP--------CFVDDVFIRVLNRSLPLFMTLAWIYSVAMIIKGVVYEKEARLKETMRIMG 683

  Fly   103 VGSCLQWVAWYIQTFIIFLIGSSII--TLFWKLVLPNSEISFMPFTHWSMALFVLLVLSHCTICF 165
            :||.:.|.:|:|.:::.||..::::  .|.|..:||.|:    |    ::..|.|...:..||..
Zfish   684 LGSGMLWFSWFISSYLPFLFSAALLIAALKWGDILPYSD----P----AVVFFFLAAFATATIML 740

  Fly   166 SFLMSSLISTTYRISLVTFLALIATYLPFLILHSKGCSEGLNVFLSL--FLLSGLQVLVVGI-C- 226
            .||:|:..|.....:....|.....|||:::     |........|.  .|.|.|..:..|. |
Zfish   741 CFLISTFFSRANLAAACGGLIYFTLYLPYVL-----CVAWREYLTSTHRILASFLSPVAFGFGCE 800

  Fly   227 ---MWEDYGEGLQWGNLFETSWPGGTLSVGYILLVMILASFLSLLLCLYLEKIRPGPYGVPQPWH 288
               .:|:.|.|:||.||..:...|.|.|....::::...:.:..|...|:|.:.||.||:|:||:
Zfish   801 YFSQYEEQGVGIQWFNLKSSPMEGDTYSFNTSIMMLYADALIYALATWYIEAVFPGQYGIPRPWY 865

  Fly   289 FPCTRCCSTESLLPYSRLFNRIFGI-------------YSAAPDEERPDLQLIEPDPVDKIAGVQ 340
            |                    ||.:             ...||.||: |.: ||.:|.:.|.||.
Zfish   866 F--------------------IFQLNYWGGVPLELGLPIPPAPREEQ-DAR-IEAEPTNLILGVS 908

  Fly   341 IRGLSKTF--GKMEVVKNVSFDMFEGQITVLMGHNGAGKTTLISMLAGFISPTSGTALINGFDIR 403
            ||.|.|.:  |....|.:::...:|||||..:|||||||||.:|:|.|...||:||..:.|.|||
Zfish   909 IRNLVKIYKKGAKLAVNHLNIKFYEGQITSFLGHNGAGKTTTMSILTGLFPPTAGTIYVKGMDIR 973

  Fly   404 QERRQAQRCIGLCPQQNVLFKHLSSVSHIQLFSRLRGLRGAEVKSEVQNYLKKLNLQEKKRLAAR 468
            .:....:|.:|:|||.||||..|:...|:..:.|::|:...||..|:.:.|:.:.||.|:....:
Zfish   974 SDMDIIRRTLGVCPQHNVLFDILTVEEHVWFYGRMKGMSLEEVNKEMNSLLEDVGLQHKRFEQTK 1038

  Fly   469 NLSGGTQRRLSVACSLCGGVKVLICDEPSTGLDPSARRELWRLILEAKEGCTILLTTHQLDDGEV 533
            |||||.||:||||.:..||.||::.|||:.|:||.:||.:|.|:|:.:||.||:|:||.:|:.::
Zfish  1039 NLSGGMQRKLSVAIAFIGGSKVVVLDEPTAGVDPYSRRGIWDLLLKYREGRTIILSTHYMDEADL 1103

  Fly   534 LGDRVVIISDGQLRCIGSLPFLKKQVDASCLITCEARKR-------------------------- 572
            ||||:.|||.|:|.|.|:..|||.::.....:|...|:.
Zfish  1104 LGDRIAIISQGKLCCCGTPLFLKARLGTGYYLTLVKREMHRTPSNTSSGKIPSAASPKDSDSSVS 1168

  Fly   573 -----------CDLEKLTSLISRHVGTIQPFSIKGRDVCYKLP--LSKSKYFSSLFRDLESQMNI 624
                       .|:..|.:|..::|...|.....||:....||  .|:....:....:|:.:...
Zfish  1169 DDTGLGSEENGFDVAALMALAQQYVPDAQLVEDIGREAVINLPNAASEDGTLALFLNELDKRQGE 1233

  Fly   625 LGVRGFSLSSVSLEEIFMSFGAE---DLN------SRQSGGAEKRDDDD------RDDDEENEVQ 674
            .||..:.||..:|||||:....|   |.:      |::..||...|.|.      |.:.:|.:..
Zfish  1234 FGVVSYGLSDTTLEEIFLRVAEETGVDADPEDPPVSQEPQGAPSEDRDAARKRSIRKEAQETDPL 1298

  Fly   675 DGNVRS-----------CKKQWRAMMTKKVMALYDNKVYFLLLLLTPIVYYITTLMMA-TKPHHS 727
            .|:.:|           | :|.||:.||::...:.::......::.|.|:.:..|:.: ..|...
Zfish  1299 SGDGQSDSAPLTGCFHTC-QQLRALFTKRLKYAFRSRRGIFAQIVLPAVFVLIALLFSLIVPPFG 1362

  Fly   728 GRPTFNISD--YGVDKFTI-----------------LLSVP---------------VSKSYTE-- 756
            ..|:..:..  || ::||.                 ||..|               ::|:.|:
Zfish  1363 KYPSLELQPWMYG-EQFTFFSNDAPQDPAMQNLLKALLDPPGFGTKCMQPNGDTECLAKAETKFV 1426

  Fly   757 --------------------------ERRADSIASL------------------IKGKLKLIVVS 777
                                      |...:.|..:                  |.|.:...:..
Zfish  1427 RPQIPYSMWQLFHNGNFSIEKPSPECECSTEKIRRMLPECPEGAGGVPPPQMQQITGDILQNLTG 1491

  Fly   778 EQIKDYV-------------DDKW--KSREG-------------------------RREINFVSM 802
            ..|.||:             ..||  :.|.|                         ||..|..
Zfish  1492 RNISDYLIKTYPQILKKSLKTKKWVNEFRYGGFSLGAKSSLTMSEPHHLEESVLAIRRRYNIA-- 1554

  Fly   803 AIDTGDRTGLI-----------------------GWVGPRHYVHAAPMILNLVYNALAQELIGP- 843
              :.|....|:                       ||       ||....:|::.|.|.:..:.|
Zfish  1555 --ENGSLDQLLQRLPDVLSGLTSQNNVKVWFNNKGW-------HAMASFVNIMNNGLLRANLPPK 1610

  Fly   844 ----KISIEVTSVPFTLRKK---EDFLISNNGDI-----PIYVIGYVSIAMIIFSSAVIQERVSH 896
                |..|...:.|..|.|:   |..|::.:.|:     .|:.:.:|..:.::|   :|:||||.
Zfish  1611 TERRKYGITAYNHPLNLTKEQLTEMALMTTSVDVLVSICVIFAMSFVPASFVLF---LIEERVSK 1672

  Fly   897 MKMLQEVSGLEMITYWLSHLAFDMV--------VFFILV---------------LALLLPLYGYA 938
            .|.||.|||::.|.||.::..:|||        |.||.:               |.|||.|||::
Zfish  1673 SKHLQFVSGVKPILYWTTNYVWDMVNYTVPATMVVFIFISFQQESYVSEKNLPALVLLLLLYGWS 1737

  Fly   939 PWYLLLCVLFFTGLAGLIF-IYFLISMLSATFLAVSMILLSVIIGSLILMILGALALIFKMVYVA 1002
                         :..|:: ..|:.|:.|..::.::.|       :|.:.|.|::|.....::|.
Zfish  1738 -------------ITPLMYPASFIFSVPSTAYVVLTSI-------NLFIGINGSVATFVLELFVD 1782

  Fly  1003 IYVANMHPLIAGYNCIQKCFHYMSLCGSYISEAQNP----------LSENLTSDEMYCINPLAFL 1057
            .::..::.::.....|   |.:..|....|..|:|.          ..:||
Zfish  1783 EHLNEVNRILKKVFLI---FPHFCLGRGLIDMAKNQAMADAFQRLGTKQNL-------------- 1830

  Fly  1058 EPRCVCVNPMTW----PDMLVMLGTAIILFLLIMFFEYGSCVWYRCKGCCPYSSKGS-------- 1110
                   :|::|    .::..|....|:.||..:..:|...|.:         |:.|
Zfish  1831 -------DPLSWDFVGKNLFAMAMEGIVFFLFTVLLQYKFFVNF---------SRWSGFVLPPLG 1879

  Fly  1111 IEDPKVSREAEKIRAMDADQIGTRALVVNGVSKKYGCDQL-AVNNISFALKPSHCVGLLGPNGAG 1174
            :||..|:||.|:::  :...:|. .|:::.:||.|...:. |||.:...:....|.||||.||||
Zfish  1880 MEDEDVARERERVK--NGRALGD-ILILSDLSKVYKAGRKPAVNRLCLGIPRGECFGLLGVNGAG 1941

  Fly  1175 KTTTFKMIVGEHSIDKGNIYISGYSMRMKRNKAMKELGYCPQSDSFFEFLTGRQLLKVFLLIWGF 1239
            ||:||:|:.|:..|..|..::|..|:..:..|..:.:|||||.|:..:.||||:.|:.:..:.|.
Zfish  1942 KTSTFRMLTGDTRITYGEAFLSNQSVLTEMEKVHQLMGYCPQFDAIIDLLTGREHLEFYARLRGV 2006

  Fly  1240 PSKDLNKRCEKLADQFGFRKHLDKKITYYSGGTKRKINAAVA-CGANSLICLDEPSAGVDPASRR 1303
            |...:.|..:....:.|..::.|::...||||.|||::.|:| .||..:|.||||:.|:||.::|
Zfish  2007 PESYVEKVAQWGVQKLGLSQYADREAGGYSGGNKRKLSTAIALIGAAPVIFLDEPTTGMDPKAKR 2071

  Fly  1304 HVWTIINEVAQQGKAVLLTSHNMDEINALCSKSVILVDGSIYAMGSVQHVKNKIAKGMTLKLVVN 1368
            .:|..|..|.::|::|:||||:|:|..|||::..|:|:|....:|||||:||:...|.|:.|.::
Zfish  2072 FLWNCILSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFQCLGSVQHLKNRFGDGYTIILRLS 2136

  Fly  1369 VQPDNMVAMLTKIEDDIYMTYPNAELKEKYEFSGRLTFQISKDT-SWSEIFEYVEGNRSSWHLED 1432
            ...    |....::..|...:|..:|||:::  ..|.:|:...| |.:.:||.:..|.....:.|
Zfish  2137 TPS----AEPCPVDAYIQNAFPGIQLKERHQ--NVLQYQLPSQTCSLARVFEVLSNNYEELGIAD 2195

  Fly  1433 YSLSQPSLEDAFEEIAEER 1451
            ||:||.:|:..|...|:::
Zfish  2196 YSVSQTTLDQVFVNFAKDQ 2214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42816	NP_730301.3	CcmA	336..643	CDD:224054	124/347 (36%)
		ABC_subfamily_A	339..556	CDD:213230	98/218 (45%)
		ABC2_membrane_3	<821..1018	CDD:289468	54/233 (23%)
		CcmA	1135..1450	CDD:224054	111/317 (35%)
		ABC_subfamily_A	1136..1354	CDD:213230	85/219 (39%)
abca7	XP_009304071.2	AAA	1..2220	CDD:333001	442/1709 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100045
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820