Protein Alignment CG42816 and Abca17

DIOPT Version :10

• Sequence 1: NP_730301.3
• Gene: CG42816 / 39977
• FlyBaseID: FBgn0261998
• Length: 1459
• Species: Drosophila melanogaster
• Sequence 2: NP_001026807.2
• Gene: Abca17 / 287112
• RGDID: 1560494
• Length: 1773
• Species: Rattus norvegicus
• Alignment Length: 1576
• Identity: 444/1576 - (28%)
• Similarity: 756/1576 - (47%)
• Gaps: 231/1576 - (14%)

  Fly     4 ADGSYPLY-KTGFLAVQQALSQVHIKHKCKE-----FNKTQGDI-KFPPIKDLPSPPIFKSDNSS 61
            |||.:|.| |.||||:|.|:.:..:.|...:     |...|..: :||              :.|
  Rat   198 ADGGHPGYNKEGFLAIQHAVDKAIMLHHAPKAALDMFKNLQVSVQRFP--------------SGS 248

  Fly    62 TLQDVGIMI------IVIIIFFVVVSL--TKSIVEEKELQLKVTLNLMGVGSCLQWVAWYIQTFI 118
            .:||..::|      :::::.|:.|.|  |.||:.|||.:.|..:.|||:.:.|.||||:|..|:
  Rat   249 HIQDPFLVILQNEFPLLLMLSFICVELIITNSILLEKERKQKEYMYLMGLENWLHWVAWFITFFL 313

  Fly   119 IFLIGSSIITLFW--KL----VLPNSEISFMPFTHWSMALFV-LLVLSHCTICFSFLMSSLISTT 176
            ..|:..|.:|:.:  |:    |..||..:.         :|: |:..:..||.|:|:||:.....
  Rat   314 SALVTVSGMTVLFCTKMNGVAVFRNSNTTL---------IFIFLMCFAIATIFFAFMMSTFFQRA 369

  Fly   177 YRISLVTFLALIATYLPFLIL----HSKGCSEGLNVFLSLFLLSGLQVLVVGICMWEDYGEGLQW 237
            :..:::..:....||||::.:    |.:..|:  .:...||....:.:.|..|.::|..|.|:||
  Rat   370 HVGTVIGGIVFFFTYLPYMYITFSYHQRTYSQ--KILSCLFSNVAMAMGVRFISLFEAEGTGIQW 432

  Fly   238 GNLFETSWPGGTLSVGYILLVMILASFLSLLLCLYLEKIRPGPYGVPQPWHF----PCTRCCSTE 298
            .|: .:.|  |..|...:|::::|.|||..|:...:|.:.|...|:|:.|:.    |..|
  Rat   433 RNM-GSVW--GDFSFTQVLVMLLLDSFLYCLVAFLVESLFPRKIGMPKSWYIFAKCPLWR----- 489

  Fly   299 SLLPYSRLFNRIFGIYSAAPDEERPDLQLIEPDPVDKIAGVQIRGLSKTF----GKMEVVKNVSF 359
                 .:.|..|..:......|:......::.:|...|..::|:.|.|.|    .|...||::|.
  Rat   490 -----KKSFPVIPPLLVIGDPEKTSKGDFLQDEPAGHINAIEIQHLYKVFYTGRSKCIAVKDLSM 549

  Fly   360 DMFEGQITVLMGHNGAGKTTLISMLAGFISPTSGTALINGFDIRQERRQAQRCIGLCPQQNVLFK 424
            ::::||||||:|||||||||:.|:|.|.|.|:.|.|.|:|.:|.::..:.::.:|.|||.::||.
  Rat   550 NLYKGQITVLLGHNGAGKTTVCSVLTGLIPPSKGHAYIHGCEISKDMVRIRKNVGWCPQHDILFD 614

  Fly   425 HLSSVSHIQLFSRLRGLRGAEVKSEVQNYLKKLNLQEKKRLAARNLSGGTQRRLSVACSLCGGVK 489
            :.:...|:..:.:|:||...:...:::..|..|.|::|:...::.||||.:|:|::..:|..|.|
  Rat   615 NFTVTDHLYFYGQLKGLSHQDCHEKIEEMLHTLGLEDKRNSRSKFLSGGIKRKLAIGIALIAGSK 679

  Fly   490 VLICDEPSTGLDPSARRELWRLILEAKEGCTILLTTHQLDDGEVLGDRVVIISDGQLRCIGSLPF 554
            |||.|||::|:|.|:||.:|.|:.:.|...|:|||||.:|:.::||||:.|::.|:|:|.|:..|
  Rat   680 VLILDEPTSGMDSSSRRAIWDLLQQQKGDRTVLLTTHFMDEADLLGDRIAILAKGELQCCGTPSF 744

  Fly   555 LKKQVDASCLITCEARKRCDLEKLTSLISRHVGTIQPFSIKGRDVCYKLPLSKSKYFSSLFRDLE 619
            ||::..|...:|......||.|||..:|..|:......|..|.::.:.||......|.:||.|||
  Rat   745 LKQKYGAGYYMTIIKTPLCDTEKLAKVIYHHIPNAILESRIGEEMIFTLPKKAMPRFEALFADLE 809

  Fly   620 SQMNILGVRGFSLSSVSLEEIFM----------SFGAEDLNSRQSGGAEKRDDDDR--------- 665
            .:...||:..|..|..::||:|:          :...|...|.:......|...||
  Rat   810 QRQTELGISTFGASVTTMEEVFIRVCKLADPSTNVLTEKRPSLRHLPRNHRVPVDRIKCLHSRIF 874

  Fly   666 --DDDEENEVQDGNVRSCKKQWRAMMTKKVMALYDNKVYFLLL---LLTPIVYYITTLMMATKPH 725
              ..|:...:..|....| :|:.||:.|||  .:..:.:.|:|   :|.|:|..:.:|..
  Rat   875 SLSSDQPIRLNTGFSLLC-QQFYAMLLKKV--AFSRRNWMLVLSVQILLPLVIIMLSLSF----- 931

  Fly   726 HSGRPTFNISDYGVDKFTILLSVPVSKSY---------TEERRADSIASLIKGKLKLIVVSEQIK 781
                  ||.....:|...:.|::   ::|         .|..|.|  ..|....:|::|.:.|:.
  Rat   932 ------FNFKLRKLDNVPLELTL---QTYGQTIVPFFIAENSRLD--PQLSDNFVKMLVAAGQVP 985

  Fly   782 DYVDDK------WKSREGRREIN--FVSMAI--DTGDRTGLIGWVGPRHYVHAAPMILNLVYNAL 836
            ..:...      .|::|...:.:  :|..|.  |..|.|.:......:.| |:..:.|.||.|.|
  Rat   986 LRIQGSVENFLLKKAKEAPEDFDKLYVVAASFEDVNDHTTVKALFNNQAY-HSPSLALALVDNVL 1049

  Fly   837 AQELIGPKISIEVTSVP-----FTLRK-------KEDFLISNNGDIPIYVIGYVSIAMIIFSSAV 889
            .:.|.|...||..|:.|     ..|.:       |..:|:.|.    ::.|.::|.:   ||...
  Rat  1050 FKLLSGANASITTTNYPQPQTAMELSETILYQGPKGHYLVVNF----LFGIAFLSSS---FSILT 1107

  Fly   890 IQERVSHMKMLQEVSGLEMITYWLSHLAFDMVVFFILVLALLLPLYGY----------APWYLLL 944
            :.|:....|.||.:||:.|..:|||.|.:|::.|.:..|.|:|..:.|          .|..:|:
  Rat  1108 VGEKSIKSKNLQFLSGVSMAAFWLSALLWDLISFLVPTLLLVLVFFWYKEEAFAHPQSIPAVVLI 1172

  Fly   945 CVLFFTGLAGLIF-IYF-----------LISMLSATFLAVSMILLSVI-----IGSLILM-ILGA 991
            .:|:...:..|:: :.|           |::||  |||::|.::|..:     :|...|. .|..
  Rat  1173 MMLYGWAIIPLVYTVSFSFKTPGSGCVKLVAML--TFLSISPVVLVTVTSEKDLGYTELSDTLDH 1235

  Fly   992 LALIFKMVYVAIYVANMHPLIAGYNCIQKCFHYMSLCGSYISEAQNPLSENLTSDEMYCINPLAF 1056
            :.|||....:.:..:|::     ||     |.....|.          ::||:  ::.|.:   .
  Rat  1236 IFLIFPGHCLGMAFSNLY-----YN-----FEIKKFCN----------AKNLS--DIDCND---V 1275

  Fly  1057 LEPRCVCVNPMTWPDM--------LVMLGTAIILFLLIMFFEYGSCVWYRCKG-CCPYSSK---- 1108
            ||...|..|...|..:        |.:||...|..|.:........:..|..| .|....:
  Rat  1276 LEGYVVQKNIYAWESLGIGKYLTALAILGPVYITLLFLTEANAFCALKARLSGFFCKQKLRMLLN 1340

  Fly  1109 -GSIEDPKVSREAEKIRAMDADQIGTRALVVNGVSKKY--GCDQLAVNNISFALKPSHCVGLLGP 1170
             ...||..|..|||.|:......|....|||..:||.|  ....||||.:||.:|...|.||||.
  Rat  1341 VTGAEDEDVLEEAENIKYHLDTLIKKSPLVVKELSKVYKEKVPLLAVNKVSFVVKEKECFGLLGL 1405

  Fly  1171 NGAGKTTTFKMIVGEHSIDKGNIYISGYSMRMKRNKAMKELGYCPQSDSFFEFLTGRQLLKVFLL 1235
            ||||||:.|.|:..|..|..|:.::.|:::|....|..:.:||||:.|:...|:|||::|.:...
  Rat  1406 NGAGKTSIFNMLTREQPITSGDAFVKGFNIRTDMAKVQQWIGYCPEFDALLNFMTGREMLVMHAR 1470

  Fly  1236 IWGFPSKDLNKRCEKLADQFGFRKHLDKKITYYSGGTKRKINAAVA-CGANSLICLDEPSAGVDP 1299
            |.|.|...:....:.:.:......:.||.:..||.|.||.::.|:| .|..::|.|||||.|:||
  Rat  1471 IRGIPECHIKTCVDMILENLLMCVYADKLVKTYSDGNKRVLSTAIALLGEPTVILLDEPSTGMDP 1535

  Fly  1300 ASRRHVWTIINEVAQQGKAVLLTSHNMDEINALCSKSVILVDGSIYAMGSVQHVKNKIAKGMTLK 1364
            .:||.||..:..|.:.||.:::|||:|:|..|||::..|:|.|....:||.||:|::...|.:|:
  Rat  1536 VARRLVWDAVGRVRESGKTIVITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSRFGSGYSLQ 1600

  Fly  1365 LVVNVQPDNMVAMLTKIEDDIYMTYPNAELKEKYEFSGRLTFQI-SKDTSWSEIFEYVEGNRSSW 1428
              ..|:......||.:.:..:.:|:|.:.|:::::  ..:.:.: .::.||:::|..:|..:..:
  Rat  1601 --AKVRRKWQQQMLEEFKAFVDLTFPGSSLEDEHQ--SMVQYYLPGQNLSWAKVFGIMEQAKKDY 1661

  Fly  1429 HLEDYSLSQPSLEDAF 1444
            .|||||:||.||||.|
  Rat  1662 VLEDYSISQLSLEDIF 1677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42816	NP_730301.3	rim_protein	<81..1451	CDD:130324	421/1486 (28%)
Abca17	NP_001026807.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1690..1773