Protein Alignment CG42816 and osy

DIOPT Version :10

• Sequence 1: NP_730301.3
• Gene: CG42816 / 39977
• FlyBaseID: FBgn0261998
• Length: 1459
• Species: Drosophila melanogaster
• Sequence 2: XP_312290.4
• Gene: osy / 1273324
• VectorBaseID: AGAMI1_006800
• Length: 776
• Species: Anopheles gambiae
• Alignment Length: 753
• Identity: 166/753 - (22%)
• Similarity: 296/753 - (39%)
• Gaps: 162/753 - (21%)

  Fly   339 VQIRGLSKTFGKME----VVKNVSFDMFEGQITVLMGHNGAGKTTLISMLAGFISPTSGTALING 399
            |.:|...|.:|..:    ::..::..:.:|.|..|:|.:|.|||||:|.:.|.....||...:.|
Mosquito    49 VCVRRAHKIYGTKKNPNVILDGLNMTVPKGSIYGLLGASGCGKTTLLSCIVGRRRLNSGEIWVLG 113

  Fly   400 FDIRQERRQAQR-------CIGLCPQQNVLFKHLSSVSHIQLFSRLRGLRGAEVKSEVQNYLKKL 457
                  .|...|       .:|..||:..|:...:....:..|..:.|:...:|..:.....|.|
Mosquito   114 ------GRPGSRGSGVPGPRVGYMPQEVALYGEFTIRETLIYFGWIYGMTTDQVDEKTDFLCKLL 172

  Fly   458 NLQEKKRLAARNLSGGTQRRLSVACSLCGGVKVLICDEPSTGLDPSARRELWRLILE-AKEG-CT 520
            .|....|. .:|||||.|||:|:|.:|....::||.|||:.|:||..|:.:|..::| .|.| .|
Mosquito   173 QLPNASRF-VKNLSGGQQRRMSLAAALLNEPELLILDEPTVGVDPVLRQSIWDHLVEITKSGNTT 236

  Fly   521 ILLTTHQLDD---GEVLGDRVVIISDGQLRCIGSLPFLKKQVDASCLITCEARKRCDLEKLTSLI 582
            :::|||.:::   ..|:|    ::..|:        ||.::..|..|...:|      |.|
Mosquito   237 VIVTTHYIEETRQAHVIG----LMRGGK--------FLAEESPADLLAQYQA------ESL---- 279

  Fly   583 SRHVGTIQPFSIKGRDVCYKLPLSKS---KYFSSLFRDLESQMNILGVRGFSLSSVSLE---EIF 641
                          .||..||.:.::   :..||:.:::...:.|..:...:|.....|   ||.
Mosquito   280 --------------EDVFLKLSVLQNMGKRRRSSIAQEVVEHVRIPAISNPALDLSPEEDHGEIS 330

  Fly   642 MSFGAEDLNSRQSGGAEKRDDDDRDD--DEENEVQDGNVRSCK----KQWRAMMTKKVMALYDNK 700
            ..||  |..|..|.|.:....:.:..  ..|.:.:...|...|    ...||::.|..:.::.|.
Mosquito   331 GEFG--DNISMSSRGPDAVTPEIQAPPLPPEEDTKTPLVEYLKFIKPNHMRALIWKNFLWMWRNV 393

  Fly   701 VYFLLLLLTPIVYYI----------TTLMMATKPHHSGRPTFNISD---YGVDKFTILLSVPVSK 752
            .....::..|:...|          ..|.:|...:......::..|   |....:::|     |.
Mosquito   394 GVMAFIIGLPVAQIILFCWAIGHDPVGLKLAVANYELEEAGYSFQDCPVYPGCNYSLL-----SC 453

  Fly   753 SYTE------------ERRADSIASLIKGKL--KLIVVSEQIKDYVDDKWKSREGRRE-----IN 798
            .|.|            ...:|::..:.:|..  .|:..|    :|.|...:..|..|:     |:
Mosquito   454 RYMEFLKNRSVVLELFSSESDALQQVSRGNAWGALVFAS----NYSDSLVERTERGRDVDDFTID 514

  Fly   799 FVSMAIDTGDRTGLIGWVGPRHYVHAAPMILNLVYNALAQELIGPKISIEVTSVPFTLRK----- 858
            ..::|:........||.:..|...:|       .::.:...||..:::.....:||...|
Mosquito   515 SANLAVTMDMSNQQIGTLLYRDIQYA-------YFDFIENILIDCEVNPSNGRIPFQWNKPVYGD 572

  Fly   859 -KEDFLISNNGDIPIYVIGYVSIAMIIFSSAVIQERVSHMKMLQEVSGLEMITYWLSHLAFDMVV 922
             |.:|.......:.:.:|.::|:|:.  |.|::.||...:.....|||:..|....||:....:|
Mosquito   573 RKPNFTDFAAPGVILTIIFFLSVALT--SGAMLIERNEGILERCLVSGITGIEILFSHVTTQFLV 635

  Fly   923 FFI---LVLALLLPLY-----GYAPWYLLLCVLFFTGLAGLIFIYFLISM-----LSATFLAVSM 974
            ...   ||:.....::     |...|.:||.:|  |||.|:.| .|::|.     .|||::|:..
Mosquito   636 MCFQTALVMVFSFSVFNLTNRGDIVWVILLTIL--TGLCGMCF-GFVVSCSCDNERSATYMAMGS 697

  Fly   975 ILLSVIIGSLILMILGALALIFKMVYVAIYVANMHPLI 1012
            .|..|::..:|..|.|                 ||||:
Mosquito   698 FLPIVMLCGIIWPIEG-----------------MHPLV 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42816	NP_730301.3	rim_protein	<81..1451	CDD:130324	166/753 (22%)
osy	XP_312290.4	CcmA	51..286	CDD:440746	71/277 (26%)
		YadH	577..772	CDD:440604	42/164 (26%)