Protein Alignment CG42816 and abca12

DIOPT Version :9

• Sequence 1: NP_730301.3
• Gene: CG42816 / 39977
• FlyBaseID: FBgn0261998
• Length: 1459
• Species: Drosophila melanogaster
• Sequence 2: XP_031748843.1
• Gene: abca12 / 101731410
• XenbaseID: XB-GENE-6041943
• Length: 7516
• Species: Xenopus tropicalis
• Alignment Length: 1657
• Identity: 432/1657 - (26%)
• Similarity: 745/1657 - (44%)
• Gaps: 313/1657 - (18%)

  Fly    11 YKTGFLAVQQALSQVHIKHKCKEFNKTQGDIKFPPIKDLPSPPIFKSDNSSTLQDVGIMIIVIII 75
            |..||:.:|:.:.:..|:   .:.||:..::.. ..:.:|. |.:|.|.........:.|.::|.
 Frog  5934 YSRGFVYLQENIDRAIIE---MQTNKSVANVGL-QYQSVPF-PCYKRDRFLASMGYTLPIALMIT 5993

  Fly    76 FFVVVS-LTKSIVEEKELQLKVTLNLMGVGSCLQWVAWYIQTFIIFLIGSSIITLFWKL--VLPN 137
            :.:.:| ..|.||.|||::|...:.:|||.|...:.||:|::....||..||:.|..|.  :||:
 Frog  5994 WVLFISAFVKKIVHEKEMRLHEYMRMMGVNSSSHFCAWFIESASFLLITVSILVLLLKFGQILPS 6058

  Fly   138 SE--ISFMPFTHWSMALFVLLVLSHCTICFSFLMSSLISTTYRISLVTFLALIATYLPFLILHSK 200
            |.  |.|:.|..:|:.:          |..|:|:|.....|....|...|..|.|:.||:::.:|
 Frog  6059 SNGFILFLLFLDYSLTI----------IAMSYLISVFFHNTNVAGLSGSLIYIITFFPFIVIATK 6113

  Fly   201 G--CSEGLNVFLSLFLLSGLQVLVVGICMWEDYGEGLQWGNLFETSWPGGTLSVGYILLVMILAS 263
            .  .|......|.:|..:.|...:..:..:|:...|:||.|::.:...|.:::.|::..::.:.:
 Frog  6114 SSVLSFSAKTLLCIFSPTALSNAIQYVVYYEEQSVGIQWSNMYISPLLGDSMTFGWLCWLLFIDA 6178

  Fly   264 FLSLLLCLYLEKIRPGPYGVPQPWHFP-----CTRCCSTESLLPYSR---LFNRIF--GIYSAAP 318
            .:..|:..|:..:.||.||:|.||:||     ..:||..|||.|...   .|..|.  .||....
 Frog  6179 MIYFLVGFYIRMVFPGKYGIPAPWYFPFQMSFWLKCCGLESLRPTKSSGLTFTNIMADNIYHKKG 6243

  Fly   319 DEERPDL-QLIEPDPVDKIAGVQIRGLSKTFGKMEVVKNVSFDMFEGQITVLMGHNGAGKTTLIS 382
            .|.  || .|.|.:|.|...||.:.||:|.|.....|.|::.:.:||.||.|:|||||||||.:|
 Frog  6244 AEN--DLCSLNEQEPNDLTVGVSLHGLTKVFQSKTAVNNLNLNFYEGHITALLGHNGAGKTTTLS 6306

  Fly   383 MLAGFISPTSGTALINGFDIRQERRQAQRCIGLCPQQNVLFKHLSSVSHIQLFSRLRG--LRGAE 445
            ||.|....:|||..:.|.|||....:|:..:|:|.|.:|.|.||::..|:.|:..::.  ...|.
 Frog  6307 MLTGLFGASSGTIYVYGDDIRTNLDRARSNMGVCMQYDVHFDHLTTKEHLLLYGSIKAPHWTRAH 6371

  Fly   446 VKSEVQNYLKKLNLQEKKRLAARNLSGGTQRRLSVACSLCGGVKVLICDEPSTGLDPSARRELWR 510
            :..||:..||...|...:....:.||||.:|:||:..:|.||.||:|.|||:||:||.:||.:|.
 Frog  6372 LHIEVKRNLKDTGLYNHRHKPVKALSGGMKRKLSICIALIGGSKVVILDEPTTGVDPCSRRSIWE 6436

  Fly   511 LILEAKEGCTILLTTHQLDDGEVLGDRVVIISDGQLRCIGSLPFLKKQVDASCLITC-------E 568
            :|.:.|:..||:|:||.||:.|||.||:..:..|.|:|.|:..:||::..:...:|.       |
 Frog  6437 VISKQKKDKTIILSTHHLDEAEVLSDRIAFLEQGGLKCCGTPLYLKQKFGSGYHLTLTKKFPNRE 6501

  Fly   569 ARKRCDLEKLTSLISRHVGTIQPFSIKGRDVCYKLPLSKSKY---FSSLFRDLESQMNILGVRGF 630
            .::.||:|.:|.||..|:.........|.::.|.||...::.   :.||.:.|:|:||.|.:..:
 Frog  6502 NQEECDVELVTDLIKSHIPEACLKEDVGGELVYLLPSFNAEISGAYLSLLQALDSRMNDLHIGCY 6566

  Fly   631 SLSSVSLEEIFMSFGAEDLNSRQSGGAEKRDDDDRD-------------DDEEN-EVQD----GN 677
            .:|..::||:|:..            .:..|:|::|             .:||| .|||    .|
 Frog  6567 GISDTTIEEVFLKL------------TDNLDEDEQDAMAWSSTKTVVPIPNEENLHVQDELSLTN 6619

  Fly   678 VR----------------------------------SCKKQWRAMMTKKVM------------AL 696
            .|                                  :.::.|:.::::.::            :|
 Frog  6620 YRFTDRDDQPLTNEEKLTGVSLLLKKIMAIFIKRFHNSRRNWKGLISQVLLPVLFVVIAMGLGSL 6684

  Fly   697 YDNKVYFLLLLLTPIVYYITTLMM----------------------------------------- 720
            ..:.|.|..|||||.:|..::..:
 Frog  6685 SSSAVSFPELLLTPDLYGTSSQSVAFGLYNESSSNLVSAMNSFPGIDNSCLNQNSNCLSQNGLGL 6749

  Fly   721 --------------------------ATKPHH---SGRPTFNISDYGVDKFTILLSVPVSKSYTE 756
                                      |..||.   |.:..:|:|.|.::.:.:..::    .:.:
 Frog  6750 WTSDNQSLSYGSCNCSTGAPVCDASSAAPPHRRTFSEQMLYNVSGYNMESYLLTTNL----QFIQ 6810

  Fly   757 ERRADSIASL--IKGKLKLIVVSEQIKDYVDDKWKSREGRREINFVSMAIDTGDRTGLIGWVGPR 819
            :|.......:  :..||:.: |.:.....:...|.:.:|
 Frog  6811 KRYGGWSFGIPWVSSKLETL-VPQNPNMTISKVWFNNDG-------------------------- 6848

  Fly   820 HYVHAAPMILNLVYNALAQELI----GPKISIEVTSVPF--TLRKKEDFLISNNGDIPIYVIGYV 878
              .|:.|..:|...|.|.:..:    ..:.||.|.|.|.  |:.:....:...|..|.:.|:...
 Frog  6849 --PHSLPAFINSFSNFLLRTNLPSNESDQYSISVASKPLSGTVIQTSTTVTLVNTLIALCVLAGY 6911

  Fly   879 SIAMIIFSSAVIQERVSHMKMLQEVSGLEMITYWLSHLAFDMVVFFI---LVLALL----LP-LY 935
            ||....|::.|::|..|..|.||.::|:....||:::..:|.:::.|   |.||.:    || .|
 Frog  6912 SITTASFATYVVKEHHSGAKRLQHIAGVGETCYWVTNFIYDSIIYLIPVSLSLATIAIFKLPAFY 6976

  Fly   936 GYAPW--YLLLCVLFFTGLAGLIFIYFLISMLSATFLAVSMILLSVIIGSLILMILGALALIFKM 998
            .|...  ..||.:||  |.|...::|    :|:.||.:.....::.:   .|.:.:|...:|...
 Frog  6977 DYPNLGAMSLLFILF--GFATFSWMY----LLAGTFKSPGNAFITYV---SINLFIGINTIISTS 7032

  Fly   999 VYVAIYVANMHPLIAGYNCI---------------QKCFHY--MSLCGSYISEAQNPLSENLTSD 1046
            |...:|| ...|..:.|..:               |.||.|  :.|......:.|:.:....::.
 Frog  7033 VVYFLYV-QRSPSDSDYQSLNQTYTVLTDVFKIFPQFCFGYGMIMLSQQQALQMQSAIYGGTSTT 7096

  Fly  1047 EMYCINPLAFLEPRCVCVNPMTWPDMLVMLGTAIILFLLI---MFFEYGSCVWYRCKGCCPYSSK 1108
            .::.::.|.::           ...|.:......:|.|||   :.|.:.|.|...|.......:|
 Frog  7097 NIFSMDILGWM-----------LSAMAIQGAFCFLLRLLINDGIIFSFKSFVKRNCMKSYLVVTK 7150

  Fly  1109 GSIEDPKVSREAEKIRAMDADQIGTRALVVNGVSKKY---GCDQLAVNNISFALKPSHCVGLLGP 1170
            ...||..|..|.|::   |:.|.....|.:.|::|.|   |.:.:||||::.::....|.||||.
 Frog  7151 NPEEDEDVRAERERV---DSGQADPDLLQLQGLTKVYHHVGKNMVAVNNMTLSIPAGECFGLLGV 7212

  Fly  1171 NGAGKTTTFKMIVGEHSIDKGNIYISGYSMRMKR----NKAMKELGYCPQSDSFFEFLTGRQLLK 1231
            |||||||||||:.|:.:..||||.:...:..::.    |......|||||.|:..|.|||.:.|.
 Frog  7213 NGAGKTTTFKMLTGDVAPSKGNIQVRNNAGNLENVLGFNTDWSAFGYCPQEDALDELLTGEEHLY 7277

  Fly  1232 VFLLIWGFPSKDLNKRCEKLADQFGFRKHLDKKITYYSGGTKRKINAAVA-CGANSLICLDEPSA 1295
            .:..:.|.|.|.:......|..:....::.|:....||.||:||::.|:| .|..|::.|||||:
 Frog  7278 FYARLHGIPEKKIKAVSFSLLQKLQLVQYKDRTTAAYSCGTRRKLSTALALIGRPSILLLDEPSS 7342

  Fly  1296 GVDPASRRHVWTIINEVAQQGKAVLLTSHNMDEINALCSKSVILVDGSIYAMGSVQHVKNKIAKG 1360
            |:||.::||:|.||:|..::..||:||||:|:|..|||::..|:|.|....:||:||:|::...|
 Frog  7343 GMDPKTKRHLWKIISEEVKEKCAVVLTSHSMEECEALCTRLAIMVKGKFQCIGSLQHIKSRFGSG 7407

  Fly  1361 MTLKLVVNVQPDNMVAMLTKIEDDIYMT--YPNAELKEKY----EFSGRLTFQISKDTSWSEIFE 1419
            .|:|:.:.....|:.|:.:      :|.  :||..||:::    |:...:|     ....:.||:
 Frog  7408 FTVKMHLKDSSVNVEALTS------FMCRHFPNTYLKDQHFTMVEYHVPVT-----AGGVAGIFD 7461

  Fly  1420 YVEGNRSSWHLEDYSLSQPSLEDAFEEIAEER 1451
            .:|.|:|...:..:|:||.:|::.|...|:.:
 Frog  7462 LLEANKSDLDIIHFSVSQTTLDEVFINFAQSQ 7493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42816	NP_730301.3	CcmA	336..643	CDD:224054	116/318 (36%)
		ABC_subfamily_A	339..556	CDD:213230	89/218 (41%)
		ABC2_membrane_3	<821..1018	CDD:289468	53/212 (25%)
		CcmA	1135..1450	CDD:224054	113/328 (34%)
		ABC_subfamily_A	1136..1354	CDD:213230	89/225 (40%)
abca12	XP_031748843.1	rim_protein	4..>82	CDD:130324
		rim_protein	5675..7493	CDD:130324	432/1655 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010