Protein Alignment CG42816 and abca9

DIOPT Version :9

• Sequence 1: NP_730301.3
• Gene: CG42816 / 39977
• FlyBaseID: FBgn0261998
• Length: 1459
• Species: Drosophila melanogaster
• Sequence 2: XP_031750505.1
• Gene: abca9 / 100496782
• XenbaseID: XB-GENE-6464273
• Length: 1608
• Species: Xenopus tropicalis
• Alignment Length: 1520
• Identity: 372/1520 - (24%)
• Similarity: 678/1520 - (44%)
• Gaps: 293/1520 - (19%)

  Fly    69 MIIVIIIFFVVVSLTKSIVEEKELQLKVTLNLMGVGSCLQWVAWYIQTFIIFLIGSSIITLFWKL 133
            |..|.:|:.:.:.:|:...|.||     ||.||.:.....|::|.:......||.::::||..|
 Frog   230 MCYVSLIYLLSLYVTRERYEMKE-----TLRLMQLKDLAFWLSWGLLYAGYILIVANLMTLITK- 288

  Fly   134 VLPNSEISFMPF----THWSMALFVLLVLSHCTICFSFLMSSLISTTYRISLVTFLALIATYLPF 194
                      ||    :.:.:.:|:..:.....:.|:|::|:|..:....::..|...:......
 Frog   289 ----------PFIFMTSSYGVIMFLFFLYGVALMSFTFMLSALFRSPRATAVAGFFITLFLSAVG 343

  Fly   195 LILHSKGCSEGLNVFLSLFLLSGLQV-LVVGICMWEDYGEGLQWGNLFETSWPGGTLSVGYILLV 258
            |:|..|...:.|.|.||:|......| |:..:.|..|. ||:.:.:|.     |.:..:....:.
 Frog   344 LVLLRKDFPQALAVLLSIFPQFAFAVGLLQSVHMDSDL-EGVYFSDLM-----GDSSHMLSCFIS 402

  Fly   259 MILASFLSLLLCLYLEKIRPGPYGVP-QPWHFPCTRCCSTESLLPYSRLFNRIFGIYSAAPDEER 322
            ::|.|...::|.||.||:....:||. :|..|......|.|...|       :.|....:.:...
 Frog   403 LVLDSVFYMILTLYFEKVLADKHGVKHEPLFFLKASYWSKEKPSP-------LMGQTDYSGESSL 460

  Fly   323 PDLQLIEPDPVDKIAGVQIRGLSKTFG----KMEVVKNVSFDMFEGQITVLMGHNGAGKTTLISM 383
            .|.....||.:.....::|.|:.|||.    ..|.::.:..:::|||||.|:||:|||||||:::
 Frog   461 GDFVEKVPDDLHGKEAIRIHGVKKTFSDKDKSTEALRGLDLNIYEGQITALLGHSGAGKTTLLNI 525

  Fly   384 LAGFISPTSGTALINGFDIRQER--RQAQRCIGLCPQQNVLFKHLSSVSHIQLFSRLRGLRGAEV 446
            |:|....:.|:|.|..:.:...|  .:.::.:|.|||.::.|..|:...::.:|:.::|:...:|
 Frog   526 LSGMYPASGGSATICNYKLSNMRHLEEIKKRVGFCPQGDIKFDPLTVKENLMVFAMIKGIPTKQV 590

  Fly   447 KSEVQNYLKKLNLQEKKRLAARNLSGGTQRRLSVACSLCGGVKVLICDEPSTGLDPSARRELWRL 511
            ..:||..|..|.:.:.:...|..||||.:|:|:...::.|..:||:.|||:.||||.:|..:|.:
 Frog   591 AHKVQKVLSDLQMNDIENTEAITLSGGQRRKLTFGIAILGDPQVLLLDEPTAGLDPCSRHHVWTI 655

  Fly   512 ILEAKEGCTILLTTHQLDDGEVLGDRVVIISDGQLRCIGSLPFLKKQVDASCLITCEARKRCDLE 576
            :.|.|.....|.:|..:|:.::|.||..:||.|:|:|:||..|||::......:..:....||:|
 Frog   656 LKENKADRVTLFSTQFMDEADILADRKAVISKGRLKCVGSSLFLKRKWGIGYHLRMQVSPSCDVE 720

  Fly   577 KLTSLISRHVGTIQPFSIKGRDVCYKLPLSKSKYFSSLFRDLESQMNILGVRGFSLSSVSLEEIF 641
            .:||:|.:.:.:.:..:....::.|.||......|..||..|:.|:. ..:..:.:|..:|:::|
 Frog   721 LMTSIIKQRIPSAKLTAQNEEELTYALPFENMDVFPDLFSHLDGQVG-NSIVSYGVSMTTLDDVF 784

  Fly   642 MSFGAE--------DLNSRQSGGAEKRDDDDRDDDEENEV--QDGNVR-SCKKQWRAMMTKKVMA 695
            :....|        |:.:.:|..||.|.|...:.:|...:  ..|||. |..:.||    ::|:|
 Frog   785 LKLEGEGEIESGDYDVFNPESRTAEDRYDISAEMEESLLLMSDSGNVTLSGWELWR----QQVLA 845

  Fly   696 L---------YDNKVY--FLLLLLTPIVYYITTLMMATKPHHSGR-------PTFNISDYGVDKF 742
            :         :|.|..  .||||:..|:..|.:::||   |.|.:       |:......|
 Frog   846 VARIRFLKLRHDTKSLRSILLLLVLFILASILSIIMA---HISNKFISWELTPSLYFQSPG---- 903

  Fly   743 TILLSVPVSKSYTE----ERRADSIASLIKGKLKLIVVSEQIKD--YVDDKWKSR------EGRR 795
                 ..::|.||:    .....||...| |.:|...::.|:.:  |..|..|.|      :..:
 Frog   904 -----SRLNKYYTDLLIHNNTGSSIDDFI-GAVKEQNIAVQVANGKYDMDTIKYRGAIEVSQAEK 962

  Fly   796 EINFVSMAIDTGDRTGLIGWVGPRHYVHAAPMILNLVYNALAQELIGPKIS--IEVTSVPFTLRK 858
            ..||..:|             .|:.: :|.|::||::.|||.:..   |:|  :.|.:.|.|:
 Frog   963 GYNFTIVA-------------NPKAH-NALPVLLNIISNALLKVF---KVSEHVRVWNHPITM-- 1008

  Fly   859 KEDFLISNNGDIPIYVIGYVSIA-MIIFSSAVI---------QERVSHMKMLQEVSGLEMITYWL 913
                     .::.|:...|:||. .:||:|.:.         ..|::....|: ::||....||.
 Frog  1009 ---------DEMDIHHKTYISIMFFMIFASGLSPHIAMSSTEDNRINARTQLR-LAGLFPSAYWF 1063

  Fly   914 SHLAFDMVVFFILVLALLLPLYGYAPWYLLLCVLF-FTGLAGLIFIYFLISMLSATFLAVSMI-- 975
            .....|:::::.|:             :|:..:|| |..     :.|||::.::|..:...|.
 Frog  1064 GQALVDVILYWSLL-------------FLMTAILFAFNN-----YSYFLLNFITAMVMIAGMFGY 1110

  Fly   976 ---------LLSVIIG---------SLILMILGALAL-----IFKMVYVAIYVANMHPLIAGYNC 1017
                     ::|.|.|         ||..:|:.....     ||...|:.:::   .|:...|..
 Frog  1111 GMAVILYVYVISFIFGKGKIHRDSWSLFFVIITFFPASNEISIFPWFYIYLFI---FPVTTLYGI 1172

  Fly  1018 IQKCFHYMSLCGSYISEAQNPLSENLTSDEMYCINPLAFLEPRCVCVNPMTWPDMLVMLGTAIIL 1082
            :                       :.|.|       |.||:.....:.|.| |.:.:     ||.
 Frog  1173 M-----------------------DYTED-------LQFLQEADNFILPCT-PYLHI-----IIF 1201

  Fly  1083 FLLIMFFEYGSCVWYRCKGCCPYSSKGSIEDP--KVSRE--------------------AEKIRA 1125
            |.|:.|.|:            .:..:....||  ::||.                    |||.|.
 Frog  1202 FGLLWFLEW------------KFGLRSLTTDPLFRISRRNMTVKKNPEELGNDVDEDVLAEKERV 1254

  Fly  1126 MDADQIGT----RALVVNGVSKKYGCD----------QLAVNNISFALKPSHCVGLLGPNGAGKT 1176
            .:|..:..    ..::|:.:.|:|...          :.|..||||.::....:|||||||||||
 Frog  1255 KNAATVANVEEKPVIIVDSLRKEYKVKKRGSFFKKNRKAATKNISFCVRKGEVLGLLGPNGAGKT 1319

  Fly  1177 TTFKMIVGEHSIDKGNIYISGYSMRMKRNKAMKE---LGYCPQSDSFFEFLTGRQLLKVFLLIWG 1238
            |:..|:.||.....|.:.:.|       |...:.   ||||||.:..:..||.::.|:::..:.|
 Frog  1320 TSMYMLAGEVKPTAGEVVLCG-------NDPAESTGFLGYCPQDNPLWPNLTVKEHLEIYAAVKG 1377

  Fly  1239 FPSKDLNKRCEKLADQFGFRKHLDKKITYYSGGTKRKINAAVA-CGANSLICLDEPSAGVDPASR 1302
            ...:|......::|.....::|:.|:....|.|..||:..|:: .|..:::.|||||.|:||.::
 Frog  1378 MKKEDAYIAINRVAAALELKEHMGKESRKLSLGESRKVCFAISMIGNPNIVLLDEPSTGLDPKAQ 1442

  Fly  1303 RHVWTIINEV-AQQGKAVLLTSHNMDEINALCSKSVILVDGSIYAMGSVQHVKNKIAKGMTLKLV 1366
            :.:|..|... ..:.:..:||:|.|:|..|:|.:..|:|.|.:..:||:|.:|:|..||..|:
 Frog  1443 QRLWRAIRAAFKNKDRGAILTTHYMEEAEAVCDRVAIMVSGKLRCIGSIQQLKSKFGKGYLLE-- 1505

  Fly  1367 VNVQPDNMVAMLTKIEDDIYMTYPNAELKEKYEFSGRLTFQISKDT--SWSEIFEYVEGNRSSWH 1429
            :.|:..:.|   .:|.::|...:|:|..:::  ||..|.::|..|.  |.|:.|..:|..:.:::
 Frog  1506 IKVKETHQV---DQIHNEIIRIFPHAARQDR--FSSLLVYKIPMDNVQSLSQAFLLLEEAKRAYN 1565

  Fly  1430 LEDYSLSQPSLEDAFEEIAEERRKK 1454
            :|:||.||.:||..|.|:|:|:.|:
 Frog  1566 IEEYSFSQSTLEQVFIELAKEQEKE 1590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42816	NP_730301.3	CcmA	336..643	CDD:224054	94/312 (30%)
		ABC_subfamily_A	339..556	CDD:213230	75/222 (34%)
		ABC2_membrane_3	<821..1018	CDD:289468	47/234 (20%)
		CcmA	1135..1450	CDD:224054	99/331 (30%)
		ABC_subfamily_A	1136..1354	CDD:213230	69/232 (30%)
abca9	XP_031750505.1	rim_protein	<170..1595	CDD:130324	372/1520 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010