Protein Alignment CG42816 and abcg8

DIOPT Version :9

• Sequence 1: NP_730301.3
• Gene: CG42816 / 39977
• FlyBaseID: FBgn0261998
• Length: 1459
• Species: Drosophila melanogaster
• Sequence 2: NP_001108041.2
• Gene: abcg8 / 100136850
• ZFINID: ZDB-GENE-050517-41
• Length: 684
• Species: Danio rerio
• Alignment Length: 748
• Identity: 149/748 - (19%)
• Similarity: 271/748 - (36%)
• Gaps: 234/748 - (31%)

  Fly   350 KMEVVKNVSFDMFEGQITVLMGHNGAGKTTLISML-----AGFISPTSGTALINGFDIRQERRQA 409
            |..|:|:::..:..||:..::|.:|.|||:|:.::     .|  |..||..||||..  ..|...
Zfish    90 KQTVIKDLNLHVHSGQMLAVIGSSGCGKTSLLDIITCRDEGG--SMNSGEILINGKP--STRSLV 150

  Fly   410 QRCIGLCPQQNVLFKHLSSVSHIQLFSRLR---GLRGAEVKSEVQNYLKKLNLQE--KKRLA--- 466
            ::.|....|.:.|..||:....:...::||   .....:....|.:.:.:|.|::  ..|:.
Zfish   151 KKSIAHVRQDDRLLPHLTVRETLAFVAKLRLPANFSQKQRDQRVDDVIAELRLRQCAHTRVGNEY 215

  Fly   467 ARNLSGGTQRRLSVACSLCGGVKVLICDEPSTGLDPSARRE----LWRLILEAKEGCTILLTTHQ 527
            .|.:|||.:||:|:|..|.....:||.|||::|||......    |:||   |:....:||:.||
Zfish   216 VRGVSGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTAHNLVITLYRL---ARGNRLVLLSVHQ 277

  Fly   528 -LDDGEVLGDRVVIISDGQLRCIGSLPFLKKQVDASCLI-----------------------TCE 568
             ..|...|.|.||::|.|.....|.   .|..|.....:                       |.|
Zfish   278 PRSDIFQLFDLVVLLSSGSAVYCGQ---AKDMVSYFTTLGYPCPRYCNPSDYYVDLISIDRRTPE 339

  Fly   569 ARKRCDLEKLTSLISRHVGTI---QPFSIKGRDVC----YKLPLSKSKYFSSLFRDLESQMNILG 626
            ...:| |||.:.|.::.:..:   :.|..|. :||    .:.|.|
Zfish   340 KEAQC-LEKASMLAAQFLEKVKNNEDFMWKS-EVCGPPALEAPQS-------------------- 382

  Fly   627 VRGFSLSSVSLEEIFMSFGAEDLNSRQSGGAEKRDDDDRDDDEENEVQDGNVRSCKKQWRAMMTK 691
                |:.|||::|..::.                       .::.:...|.|.    |:..::.:
Zfish   383 ----SVPSVSMKESVITV-----------------------SKQKDQLPGKVH----QFTTLIRR 416

  Fly   692 KVMALYDNKVYFLLLLLTPIVYYITTLMMATKPHHSGRPTFNISDYGVD---------------K 741
            :|...|.:       |:|.:|:.:..|:|:..   .|...|..::.|:.               .
Zfish   417 QVFNDYRD-------LVTLVVHGLEALLMSLL---IGFLYFGCTEEGLSIQDTVALLYMIGALTP 471

  Fly   742 FTILLSVPVSKSYTEERRADSIASLIKGKLKLIVVSEQIKDYVDDKWKSREGRREINFVSMAIDT 806
            |.::|.| ::|.::|  ||              ::..:::|          |...:.....|...
Zfish   472 FAVVLDV-IAKCHSE--RA--------------MLYHELED----------GMYSVTPYFFAKVL 509

  Fly   807 GDRTGLIGWVGPRHYVHAAPMILNLVYNALAQELIGPKISIEVTSVPFTLRKKEDFLISNNGDIP 871
            |:.        |.|      ....|||......|.|    :.|....|.|    :||:
Zfish   510 GEL--------PEH------CAFTLVYGVPIYWLAG----LNVAPDRFLL----NFLL------- 545

  Fly   872 IYVIGYVSIAMIIFSSAVIQERVSHMKMLQEVSGLEMITYWLSHLAFDMVVFFILVLALLLPLYG 936
            :::..|.|.:|.:|.:|.       :..||..|.:....:.:.:|....|:       .|..::.
Zfish   546 VWLTVYCSRSMALFVAAA-------LPTLQTSSFMGNALFTVFYLTAGFVI-------SLENMWM 596

  Fly   937 YAPWYLLLCVLFFTGLAGLIFIYFLISMLSATFLAVSMILLSVIIGSLILMILGALALIFKMV-Y 1000
            .|.|:..:..:.: |..|::.:.|.                    |:.|.:.:|.|.:.|..: .
Zfish   597 VASWFSYISFMRW-GFEGMLQVQFR--------------------GTRIPITIGNLTVEFDGIKV 640

  Fly  1001 VAIYVANMHPLIAGY------NCIQKCFHYMSL 1027
            |.:...|.:||.:.|      :.:....:|:||
Zfish   641 VEMMKMNQYPLFSCYLVLIAVSLVFILLYYLSL 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42816	NP_730301.3	CcmA	336..643	CDD:224054	84/340 (25%)
		ABC_subfamily_A	339..556	CDD:213230	64/223 (29%)
		ABC2_membrane_3	<821..1018	CDD:289468	36/203 (18%)
		CcmA	1135..1450	CDD:224054
		ABC_subfamily_A	1136..1354	CDD:213230
abcg8	NP_001108041.2	3a01204	47..674	CDD:273361	149/748 (20%)
		ABCG_White	72..301	CDD:213201	63/217 (29%)
		ABC2_membrane	413..617	CDD:279410	48/284 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000