Protein Alignment Adgf-A and ada2b

DIOPT Version :9

• Sequence 1: NP_524130.1
• Gene: Adgf-A / 39976
• FlyBaseID: FBgn0036752
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_687719.2
• Gene: ada2b / 559295
• ZFINID: ZDB-GENE-041210-77
• Length: 501
• Species: Danio rerio
• Alignment Length: 545
• Identity: 201/545 - (36%)
• Similarity: 302/545 - (55%)
• Gaps: 54/545 - (9%)

  Fly     1 MSPVIRRNLIACLTLGLCVCLSFGPGPVESRTRPKNQVDRKLLTIYGSTPHVEALLGPGRPTPDT 65
            ||.:..:::.|.:.:.|.||:|      |.::.|..:...::|
Zfish     1 MSSISLKDVSAAVMVVLLVCVS------ECKSMPDPRQREQML---------------------- 37

  Fly    66 YKTLRSAFFRYEESRSLGHDLDLNSREIKANETIMKAKLKEFDEGLVTPHLFKPSQHIFDVLDGI 130
                     :.|..:.:|.:::||..|.:.:..:...|:||     :|...|.|:.|.|.|...|
Zfish    38 ---------QQELLQQIGGNMELNEAEKRMDSLLYMLKMKE-----ITLSPFPPANHFFKVRHII 88

  Fly   131 RNTDLFKLLKKMPKGAVLHAHDTALCSTAAIINLTYYEHLWSC-QQDGDLSASALRFSKDKPQAL 194
            :.:.:||||:||||||.||.|::|:.|...::|.||..:.:.| ..||.:   ...||...|...
Zfish    89 QQSPIFKLLQKMPKGAALHIHNSAMVSVDWLLNATYRPNCYICFTWDGSV---RFMFSTSTPFPR 150

  Fly   195 SDCD-WSLLSDVRAKYG-ADKVDDYLAERLTLY---PTKKFEDNNAAWSTFMSIFNLLDGLVMYA 254
            ..|. |..|..:||..| ....|:.|...|||:   |...:...:..|..|..||..|.||:.||
Zfish   151 WGCSFWKRLDILRASLGDVTSFDNSLMRNLTLFTEDPETSYPTQDYIWKRFEKIFIALSGLITYA 215

  Fly   255 PVWADYYYKALEEFYEDGVLYLEFRSVVPTLYDMDGTEFTPMDTVRIYVETLEKFKEAHPDFIGS 319
            ||..|:.|:.|:|.|||.::|:|.|......|::|||......|:.:|....|:|:..||||||:
Zfish   216 PVLKDHIYQGLKELYEDNIMYVELRIGQAKAYELDGTTHDRAWTIEVYRNITEQFRANHPDFIGT 280

  Fly   320 RMIYAPIRYTNAEGVTGYIQTLKQIKEKYPEFVAGFDLVGQEEMGRPLRDFVDELLSIPDD--ID 382
            |:|.:..|.::...|...:|...:::.||||.||||||||:|:.|..:..|.| .||:|.:  :.
Zfish   281 RVILSAHRSSSVSRVKQAVQEAIEMQRKYPEIVAGFDLVGREDTGGSIWYFRD-ALSLPSESQLP 344

  Fly   383 FYFHAGETNWFGSTVDENLIDAILLGTKRIGHGFGLVKHPVVLDMLKKLNVAIEVNPISNQVLQL 447
            ::||||||:..|:.||.|::||:|..|.||||||.:|.|||...:.:...||:|:.|||||||:|
Zfish   345 YFFHAGETDLDGTDVDRNVLDALLFNTSRIGHGFAIVHHPVAKQLSRSRRVAVELCPISNQVLKL 409

  Fly   448 VSDFRNHPCSHFFADGYPVVISSDDPSFWKATPLTHDFYIAFLGIASQHSDLRLLKKLALNSIQY 512
            |||.||||.:...:||:|:|:||||||.:..|.|::|||..|:||....::|..||:||:|||:|
Zfish   410 VSDLRNHPAAVLMSDGHPMVVSSDDPSLFGTTGLSYDFYEVFVGIGGLSANLGTLKELAINSIRY 474

  Fly   513 SSLTGDAQFEALEKWQVKWDQFIAD 537
            |||:...|.:|:..||.||:.|||:
Zfish   475 SSLSAQLQDKAMTVWQEKWNTFIAE 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-A	NP_524130.1	A_deaminase_N	54..139	CDD:285627	17/84 (20%)
		adm_rel	66..538	CDD:273620	191/480 (40%)
		ADGF	119..531	CDD:238646	176/419 (42%)
ada2b	XP_687719.2	adm_rel	45..499	CDD:273620	189/462 (41%)
		A_deaminase_N	<46..97	CDD:285627	16/55 (29%)
		ADGF	77..493	CDD:238646	176/419 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595072
Domainoid	1	1.000	269	1.000	Domainoid score	I1799
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	363	1.000	Inparanoid score	I2141
OMA	1	1.010	-	-		QHG56251
OrthoDB	1	1.010	-	-		D197912at33208
OrthoFinder	1	1.000	-	-		FOG0003006
OrthoInspector	1	1.000	-	-		mtm8425
orthoMCL	1	0.900	-	-		OOG6_104612
Panther	1	1.100	-	-	O	PTHR11409
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3910
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770