Protein Alignment Adgf-A and ampd3a

DIOPT Version :10

• Sequence 1: NP_524130.1
• Gene: Adgf-A / 39976
• FlyBaseID: FBgn0036752
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_009301872.2
• Gene: ampd3a / 556578
• ZFINID: ZDB-GENE-110407-2
• Length: 787
• Species: Danio rerio
• Alignment Length: 641
• Identity: 124/641 - (19%)
• Similarity: 189/641 - (29%)
• Gaps: 265/641 - (41%)

  Fly    17 LCVCLSFGPGPVESRTRPKN---QVDRK--LLTIYGST-----------------------PHVE 53
            :|.|...|..|......|:|   |:..|  ::.:|.:.                       .||.
Zfish   220 ICPCPGEGEDPYSMENVPENLNYQMKMKDGIIYVYENAEALSMNKPRCLPYPDLETFAIDMSHVL 284

  Fly    54 ALLGPGRPTPDTY-----KTLRSAFFRYEESRSLGHDLDLNSREIKANETIMKAKLKEFDEGLVT 113
            |::..| || .||     ..|.|.|:.:|                ..||   .|:|||
Zfish   285 AMIADG-PT-KTYCHRRLNFLGSKFYLHE----------------MLNE---MAELKE------- 321

  Fly   114 PHLFKPSQHIFDVLDGIRNTDLFKLLKKMPKGAVLHAHDTALCSTAAI---INLTYYEHLWSCQQ 175
                         |.|:.:.|.:.:.|     ...|.|..|..:...:   |..||       :.
Zfish   322 -------------LKGVPHRDFYNVRK-----VDTHIHAAACMNQKHLLDFIQTTY-------KT 361

  Fly   176 DGD---LSASALRFSKDKPQALSDCDWSLLSDVRAKYGADKVD------DYLAERLTLYPTKKFE 231
            |.:   |..:.|:.:              |..|......|..|      |..|.|.|.:...||.
Zfish   362 DAERVVLEKAGLKLT--------------LKQVFNNLNMDPYDLTVDSLDVHAGRQTFHRFDKFN 412

  Fly   232 D--NNAAWSTFMSIF---------------------NLLDGLVMYAPVWADYYYKALEE------ 267
            .  |....|....|:                     ||.:....:|......|.::.||
Zfish   413 SKYNPVGASELREIYLKADNYINGEYFARLIKEVAHNLEESKYQHAEPRLSIYGRSPEEWESLSH 477

  Fly   268 -FYEDGVLYLEFRSV--VPTLYDMDGTEFTPMDTVRIYVETLEKFKEAHPDFIGSRMIYAPIRYT 329
             |.::.|.....|.:  ||.:||:    |.....|..:.:.||.             ::.|:
Zfish   478 WFIQNKVYSPNMRWIIQVPRIYDI----FRSRKLVPNFAKMLEN-------------VFLPL--- 522

  Fly   330 NAEGVTGYIQTLKQIKEK----YPEFVAGFDLVGQEEMGRPLRDFVDELLS---------IPDD- 380
                   :..|:...|.|    :.::|.|||.|..|.      ...|.:.|         ..||
Zfish   523 -------FEATVNPQKHKELHVFLKYVTGFDSVDDES------KHSDHMFSYKSPKPEQWTTDDN 574

  Fly   381 ----------------------------IDFYFHAGETNWFGSTVDENLIDAILLGTKRIGHGFG 417
                                        ..|..|.||.   ||..  :|:.|.|. ...|.||..
Zfish   575 PPYSYYLFHMYANIMVLNNLRKERGLSTFQFRPHCGEA---GSIT--HLVSAFLT-ADNISHGLN 633

  Fly   418 LVKHPVVLDMLKKLNVAIEVNPISNQVLQLVSDFRNHPCSHFFADGYPVVISSDDP--------- 473
            |.|.||:..:.....|.|.::|:||..|.|  ::..:|...|...|..|.:|:|||
Zfish   634 LKKSPVLQYLYYLAQVPIAMSPLSNNSLFL--EYSKNPLREFLHKGLCVSLSTDDPMQFHYTKEA 696

  Fly   474 ---------SFWKATP---------------LTHDFYIAFLGIA-----SQHSDLR 500
                     ..||.:.               |:|:....|||::     .:.:|:|
Zfish   697 LMEEYAIAAQLWKLSTCDVCEIARNSVLQSGLSHEEKKHFLGVSYLKDGPEGNDIR 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-A	NP_524130.1	adm_rel	66..538	CDD:273620	108/564 (19%)
ampd3a	XP_009301872.2	AMP_deaminase	149..781	CDD:437158	124/641 (19%)