Protein Alignment Adgf-A and AMPD3

DIOPT Version :9

• Sequence 1: NP_524130.1
• Gene: Adgf-A / 39976
• FlyBaseID: FBgn0036752
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_000471.1
• Gene: AMPD3 / 272
• HGNCID: 470
• Length: 776
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 116/557 - (20%)
• Similarity: 196/557 - (35%)
• Gaps: 200/557 - (35%)

  Fly    51 HVEALLGPGRPTPDTYKTLRSAFFRYEESRSLGHDLDLNSREIKANETIMKAKLKEFDEGLVTPH 115
            |:.||:..| || .||...|..|.   ||:...|:: ||             ::.||.|....||
Human   269 HILALITDG-PT-KTYCHRRLNFL---ESKFSLHEM-LN-------------EMSEFKELKSNPH 314

  Fly   116 LFKPSQHIFDVLDGIRNTDLFKLLKKMPKGAVLHAHDTALCSTAAIIN----LTYYEHLWSCQQD 176
                 :..::|    |..|             .|.|      .||.:|    |.:.:|.:..:.|
Human   315 -----RDFYNV----RKVD-------------THIH------AAACMNQKHLLRFIKHTYQTEPD 351

  Fly   177 G------------------------DLSASAL----------RF----SKDKPQALSDCDWSLLS 203
            .                        ||:..:|          ||    ||..|...|:     |.
Human   352 RTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASE-----LR 411

  Fly   204 DVRAKYGADKVDDYLA----ERLTLYPTKKFEDNNAAWS-TFMSIFNLLDGLVMYAP-VWADYYY 262
            |:..     |.::||.    .|:.....::.|::...:| ..:||:.       .:| .|.:..|
Human   412 DLYL-----KTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYG-------RSPEEWPNLAY 464

  Fly   263 KALE-EFYEDGVLYLEFRSVVPTLYDMDGTEFTPMDTVRIYVETLEKFKEAHPDFIGSRM--IYA 324
            ..:: :.|...:.::   ..||.:||                  :.:.|:..|:| |..:  |:.
Human   465 WFIQHKVYSPNMRWI---IQVPRIYD------------------IFRSKKLLPNF-GKMLENIFL 507

  Fly   325 PIRYTNAEGVTGYIQTLKQIKEK----YPEFVAGFDLVGQE--------------------EMGR 365
            |:          :..|:.....:    :.::|.|||.|..|                    |...
Human   508 PL----------FKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTSEQNP 562

  Fly   366 PLRDFVDEL---LSIPDDI-------DFYF--HAGETNWFGSTVDENLIDAILLGTKRIGHGFGL 418
            |...::..:   :.:.:::       .|.|  |.||.   ||..  :|:.|.|. ...|.||..|
Human   563 PYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEA---GSIT--HLVSAFLT-ADNISHGLLL 621

  Fly   419 VKHPVVLDMLKKLNVAIEVNPISNQVLQLVSDFRNHPCSHFFADGYPVVISSDDPSFWKAT--PL 481
            .|.||:..:.....:.|.::|:||..|.|  ::..:|...|...|..|.:|:|||..:..|  .|
Human   622 KKSPVLQYLYYLAQIPIAMSPLSNNSLFL--EYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEAL 684

  Fly   482 THDFYIAFLGIASQHSDLRL--LKKLALNSIQYSSLT 516
            ..::     .||:|...|..  |.::|.||:..|.|:
Human   685 MEEY-----AIAAQVWKLSTCDLCEIARNSVLQSGLS 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-A	NP_524130.1	A_deaminase_N	54..139	CDD:285627	22/84 (26%)
		adm_rel	66..538	CDD:273620	109/542 (20%)
		ADGF	119..531	CDD:238646	96/489 (20%)
AMPD3	NP_000471.1	AMP_deaminase	155..762	CDD:273618	116/557 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810