Protein Alignment Adgf-A and AMPD2

DIOPT Version :9

• Sequence 1: NP_524130.1
• Gene: Adgf-A / 39976
• FlyBaseID: FBgn0036752
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001355738.1
• Gene: AMPD2 / 271
• HGNCID: 469
• Length: 825
• Species: Homo sapiens
• Alignment Length: 508
• Identity: 97/508 - (19%)
• Similarity: 162/508 - (31%)
• Gaps: 179/508 - (35%)

  Fly    99 IMKAKLKEFDEGLVTPH-----LFKPSQHIFDVLDGIRNTDLFKLLKKMPK---GAVLH---AHD 152
            ::..::||.......||     :.|...|| .....:....|.:.:|:..|   ..::|   ..:
Human   336 VLLNEMKELAAQKKVPHRDFYNIRKVDTHI-HASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGRE 399

  Fly   153 TALCSTAAIINLTYYEHLWSCQQDGDLSASAL----------RFSK--DKPQALSDCDWSLLSD- 204
            ..|......:|||.|          |||...|          ||.|  .|...:.:   |:|.:
Human   400 QTLREVFESMNLTAY----------DLSVDTLDVHADRNTFHRFDKFNAKYNPIGE---SVLREI 451

  Fly   205 -------VRAKYGADKVDDYLAE-----------RLTLYPTKKFE-DNNAAWSTFMSIFNLLDGL 250
                   |..||.|..:.:.:::           ||::|...:.| |..|.|:
Human   452 FIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWA------------ 504

  Fly   251 VMYAPVWADYYYKALEEFYEDGVLYLEFRSVVPTLYDMDGTE-------------FTPMDTVRIY 302
                         .:...:...|.:|   ..||.|:|:..|:             |.|:....::
Human   505 -------------VMHRVHSPNVRWL---VQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVH 553

  Fly   303 VETLEKFKEAHPDFIGSRMIYAPIRYTNAEGVTGYIQTLKQIKEKYPEFVAGFDLVGQE------ 361
                   ..:||:.                             ..:.|.|.|||.|..|
Human   554 -------PASHPEL-----------------------------HLFLEHVDGFDSVDDESKPENH 582

  Fly   362 --EMGRPLRDFVDELLSIPDDIDFYF------------------------HAGETNWFGSTVDEN 400
              .:..||.:...|..:.|.....|:                        |.||....     .:
Human   583 VFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPI-----HH 642

  Fly   401 LIDAILLGTKRIGHGFGLVKHPVVLDMLKKLNVAIEVNPISNQVLQLVSDFRNHPCSHFFADGYP 465
            |:.|.:| .:.|.||..|.|.||:..:.....:.|.::|:||..|.|  .:..:|...:.:.|..
Human   643 LVSAFML-AENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFL--SYHRNPLPEYLSRGLM 704

  Fly   466 VVISSDDPSFWKAT--PLTHDFYIAFLGIASQHSDLRLLKKLALNSIQYSSLT 516
            |.:|:|||..:..|  ||..::.||.........|   :.:||.||:..|..:
Human   705 VSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCD---MCELARNSVLMSGFS 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-A	NP_524130.1	A_deaminase_N	54..139	CDD:285627	8/44 (18%)
		adm_rel	66..538	CDD:273620	97/508 (19%)
		ADGF	119..531	CDD:238646	92/483 (19%)
AMPD2	NP_001355738.1	AMPD	301..797	CDD:238644	97/508 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810