Protein Alignment Adgf-B and AMD1

DIOPT Version :10

• Sequence 1: NP_649006.2
• Gene: Adgf-B / 39975
• FlyBaseID: FBgn0036751
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_013677.1
• Gene: AMD1 / 854973
• SGDID: S000004498
• Length: 810
• Species: Saccharomyces cerevisiae
• Alignment Length: 484
• Identity: 96/484 - (19%)
• Similarity: 157/484 - (32%)
• Gaps: 181/484 - (37%)

  Fly   123 HAHDTALCSTDYLISLTYRKNLWICTAEEGCKAIAFRFSKEEPKEKPVKESIWEPMEEFRERRGE 187
            |.|.:|..:..:|:.....|               .|.||:   ||.:          ||:
Yeast   362 HVHHSACMNQKHLLRFIKHK---------------LRHSKD---EKVI----------FRD---- 394

  Fly   188 ENVTKYLTRRFSMYPFSKFISNNQAW--AHFMGIFILLDGLLCHAPIWAEYYYNALKEFAEDGVQ 250
                            .|.::.::.:  .|..|..:.:|.|..||      :.:....|.:..::
Yeast   395 ----------------GKLLTLDEVFRSLHLTGYDLSIDTLDMHA------HKDTFHRFDKFNLK 437

  Fly   251 Y------------LELRSLLPPLYCIDGDMLTIRD-----------TVAIYNSELERFRADHPDF 292
            |            |:..:.:...|..|.....|.|           .:::|...|:.:.......
Yeast   438 YNPIGESRLREIFLKTNNYIKGTYLADITKQVIFDLENSKYQNCEYRISVYGRSLDEWDKLASWV 502

  Fly   293 IGSKLIYAPLRGVE--PSVVEQYVKTAV----------------ELNKE---------FPNFMVG 330
            |.:|:|...:|.:.  |.:.:.|.||.:                |:.|.         |...::|
Yeast   503 IDNKVISHNVRWLVQIPRLYDIYKKTGIVQSFQDICKNLFQPLFEVTKNPQSHPKLHVFLQRVIG 567

  Fly   331 FDLVGQEELGRPLID------FVEP-LLKMPEH--INFYF------------------------- 361
            ||.|..|.    .:|      :.:| |.:.|::  .::|.
Yeast   568 FDSVDDES----KVDRRFHRKYPKPSLWEAPQNPPYSYYLYYLYSNVASLNQWRAKRGFNTLVLR 628

  Fly   362 -HAGETNWFGSPIDENLVDAILLGTKRIGHGYAITKHPMMMRLAKLLGIAIEVCPVSNQVLQLGV 425
             |.||.   |.|  |:||.|.|| ...|.||..:.|.|.:..|..|..:.|.:.|:||..|.|..
Yeast   629 PHCGEA---GDP--EHLVSAYLL-AHGISHGILLRKVPFVQYLYYLDQVGIAMSPLSNNALFLTY 687

  Fly   426 DYRNHPAALLLAANVPIVISSDDP-SFWHC-APLSHDFYFAFLGIAPMKADLRFLKS-----LAI 483
            |....|.......||.  :|:||| .|.:. .||..::..|        |.:..|.:     ||.
Yeast   688 DKNPFPRYFKRGLNVS--LSTDDPLQFSYTREPLIEEYSVA--------AQIYKLSNVDMCELAR 742

  Fly   484 NSIRYSALVGEEKRVGYRKWQEKWDK-WI 511
            ||:..|.            |:.:..| ||
Yeast   743 NSVLQSG------------WEAQIKKHWI 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-B	NP_649006.2	adm_rel	56..515	CDD:273620	96/484 (20%)
AMD1	NP_013677.1	AMP_deaminase	160..803	CDD:437158	96/484 (20%)